APC mutations are sufficient for the growth of early colorectal adenomas - Wikidata - awgldk - TriplyDB

APC mutations are sufficient for the growth of early colorectal adenomas

APC mutations are sufficient for the growth of early colorectal adenomas

http://www.wikidata.org/entity/Q35051664

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New era of colorectal cancer screening Quantification of crypt and stem cell evolution in the normal and neoplastic human colon Aneuploid colon cancer cells have a robust spindle checkpoint The development of duodenal microadenomas in FAP patients: the human correlate of the Min mouse Identification of flat dysplastic aberrant crypt foci in the colon of azoxymethane-treated A/J mice.Single nucleotide polymorphisms of the APC gene and colorectal cancer risk: a case-control study in Taiwan Intestinal adenomas can develop with a stable karyotype and stable microsatellites Polymorphisms in the adenomatous polyposis coli (APC) gene and advanced colorectal adenoma risk Two hits revisited again Adaptation to hypoxia and acidosis in carcinogenesis and tumor progression Analysis of chromosomal instability in human colorectal adenomas with two mutational hits at APC.Evolution of colorectal cancer: change of pace and change of direction.Evidence for tankyrases as antineoplastic targets in lung cancer.Crypt dysplasia in Barrett's oesophagus shows clonal identity between crypt and surface cells.Colorectal cancer: from epidemiology to current treatment.Enhanced stem cell survival in familial adenomatous polyposis.Analysis of somatic molecular changes, clinicopathological features, family history, and germline mutations in colorectal cancer families: evidence for efficient diagnosis of HNPCC and for the existence of distinct groups of non-HNPCC families Sporadic fundic gland polyps with epithelial dysplasia : evidence for preferential targeting for mutations in the adenomatous polyposis coli gene.Mutation cluster region, association between germline and somatic mutations and genotype-phenotype correlation in upper gastrointestinal familial adenomatous polyposis.The role of translation in neoplastic transformation from a pathologist's point of view.Cannabinoid receptors: nomenclature and pharmacological principles The human gut sterolbiome: bile acid-microbiome endocrine aspects and therapeutics.From gene mutations to tumours--stem cells in gastrointestinal carcinogenesis.Detection of K-ras gene mutation in fecal samples from elderly large intestinal cancer patients and its diagnostic significance Associations of Ki-ras proto-oncogene mutation and p53 gene overexpression in sporadic colorectal adenomas with demographic and clinicopathologic characteristics.The Wnt/β-catenin/T-cell factor 4 pathway up-regulates high-mobility group A1 expression in colon cancer More than two decades of Apc modeling in rodents Chemokine receptors in cancer metastasis and cancer cell-derived chemokines in host immune response.Lineage tracing reveals multipotent stem cells maintain human adenomas and the pattern of clonal expansion in tumor evolution.Genomic Landscape of Colorectal Mucosa and Adenomas.ROR2 is epigenetically inactivated in the early stages of colorectal neoplasia and is associated with proliferation and migration Detection of up to 65% of Precancerous Lesions of the Human Colon and Rectum by Mutation Analysis of APC, K-Ras, B-Raf and CTNNB1.Combining chromosomal arm status and significantly aberrant genomic locations reveals new cancer subtypes Investigating the fixation and spread of mutations in the gastrointestinal epithelium.Recent advances in understanding the role of diet and obesity in the development of colorectal cancer.Lessons from a decade of integrating cancer copy number alterations with gene expression profiles.Pre-tumour clones, periodic selection and clonal interference in the origin and progression of gastrointestinal cancer: potential for biomarker development.New paradigms in clonal evolution: punctuated equilibrium in cancer.Clonal evolution of colorectal cancer in IBD.Measuring cancer evolution from the genome.

P2860

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P2860

APC mutations are sufficient for the growth of early colorectal adenomas

http://www.wikidata.org/entity/Q35051664

description

2000 nî lūn-bûn

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2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2000年の論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年论文

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name

APC mutations are sufficient for the growth of early colorectal adenomas

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APC mutations are sufficient for the growth of early colorectal adenomas

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type

label

APC mutations are sufficient for the growth of early colorectal adenomas

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APC mutations are sufficient for the growth of early colorectal adenomas

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prefLabel

APC mutations are sufficient for the growth of early colorectal adenomas

@ast

APC mutations are sufficient for the growth of early colorectal adenomas

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Proceedings of the National Academy of Sciences of the United States of America

P1476

APC mutations are sufficient for the growth of early colorectal adenomas

@en

P2093

Gillet C

http://www.w3.org/2001/XMLSchema#string

Hanby A

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Ilyas M

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Lamlum H

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Papadopoulou A

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Rowan A

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Talbot I

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P2860

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

Lessons from hereditary colorectal cancer

Familial adenomatous polyposis (FAP) and its gene, APC.

The mutation rate and cancer.

Beta-catenin mutations in cell lines established from human colorectal cancers.

Prognostic value of chromosome 1p allelic loss in colon cancer.

Familial polyposis: recent advances.

Defects in mismatch repair occur after APC mutations in the pathogenesis of sporadic colorectal tumours.

The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's 'two-hit' hypothesis.

Reduced expression of molecules of the cadherin/catenin complex in the transition from colorectal adenoma to carcinoma.

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97

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10681434

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