Dyskerin is required for tumor cell growth through mechanisms that are independent of its role in telomerase and only partially related to its function in precursor rRNA processing.

Dyskerin is required for tumor cell growth through mechanisms that are independent of its role in telomerase and only partially related to its function in precursor rRNA processing.

Item
http://www.wikidata.org/entity/Q35053490
Small RNAs with big implications: new insights into H/ACA snoRNA function and their role in human diseaseDyskerin localizes to the mitotic apparatus and is required for orderly mitosis in human cellsDiverse diseases from a ubiquitous process: the ribosomopathy paradoxDissecting the expression landscape of RNA-binding proteins in human cancersSlow growth and unstable ribosomal RNA lacking pseudouridine in mouse embryonic fibroblast cells expressing catalytically inactive dyskerinZebrafish models for dyskeratosis congenita reveal critical roles of p53 activation contributing to hematopoietic defects through RNA processingAcute dyskerin depletion triggers cellular senescence and renders osteosarcoma cells resistant to genotoxic stress-induced apoptosis.Dyskerin overexpression in human hepatocellular carcinoma is associated with advanced clinical stage and poor patient prognosisRibosomopathies: mechanisms of disease.Differential Expression of Non-Shelterin Genes Associated with High Telomerase Levels and Telomere Shortening in Plasma Cell Disorders.Intron retention: a human DKC1 gene common splicing event.A new role for human dyskerin in vesicular trafficking.Mutation of EMG1 causing Bowen-Conradi syndrome results in reduced cell proliferation rates concomitant with G2/M arrest and 18S rRNA processing delay.Differential requirements for H/ACA ribonucleoprotein components in cell proliferation and response to DNA damage.Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shorteningRNA Pseudouridylation in Physiology and Medicine: For Better and for Worse.
P2860

Dyskerin is required for tumor cell growth through mechanisms that are independent of its role in telomerase and only partially related to its function in precursor rRNA processing.

Item
http://www.wikidata.org/entity/Q35053490
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Dyskerin is required for tumor ...... in precursor rRNA processing.
@ast
Dyskerin is required for tumor ...... in precursor rRNA processing.
@en
type
label
Dyskerin is required for tumor ...... in precursor rRNA processing.
@ast
Dyskerin is required for tumor ...... in precursor rRNA processing.
@en
prefLabel
Dyskerin is required for tumor ...... in precursor rRNA processing.
@ast
Dyskerin is required for tumor ...... in precursor rRNA processing.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Dyskerin is required for tumor ...... in precursor rRNA processing.
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932