Metalloproteinases: their role in arthritis and potential as therapeutic targets. - Wikidata - awgldk - TriplyDB

Metalloproteinases: their role in arthritis and potential as therapeutic targets.

Metalloproteinases: their role in arthritis and potential as therapeutic targets.

http://www.wikidata.org/entity/Q35056019

about

Functional evolution of ADAMTS genes: evidence from analyses of phylogeny and gene organization Histone deacetylase inhibitors modulate metalloproteinase gene expression in chondrocytes and block cartilage resorption Discovery and characterization of a novel inhibitor of matrix metalloprotease-13 that reduces cartilage damage in vivo without joint fibroplasia side effects An integrated computational approach to rationalize the activity of non-zinc-binding MMP-2 inhibitors Effect of the oral application of a highly selective MMP-13 inhibitor in three different animal models of rheumatoid arthritis.ADAMTS-4 and ADAMTS-5: key enzymes in osteoarthritis.Matrix metalloproteinase-8 deficiency increases joint inflammation and bone erosion in the K/BxN serum-transfer arthritis model.Evaluating Osteoarthritic Chondrocytes through a Novel 3-Dimensional In Vitro System for Cartilage Tissue Engineering and Regeneration.Aggrecan heterogeneity in articular cartilage from patients with osteoarthritis.The role of aggrecan in normal and osteoarthritic cartilage.What are the roles of metalloproteinases in cartilage and bone damage?Molecular cloning and characterization of a matrix metalloproteinase, from Caenorhabditis elegans: employed to identify homologous protein from Angiostrongylus cantonensis.CIINE Reflects Collagenase-Specific CII Breakdown in Cartilage Explant and Whole Body of Canine The emerging roles of ADAMTS-7 and ADAMTS-12 matrix metalloproteinases.The role of ADAMTSs in arthritis Potential directions for drug development for osteoarthritis.Characterization and regulation of ADAMTS-16.Sanguinarine protects against osteoarthritis by suppressing the expression of catabolic proteases Matrix metalloproteinase-3 inhibitor retards treadmill running-induced cartilage degradation in rats.Fibroblast activation protein alpha is expressed by chondrocytes following a pro-inflammatory stimulus and is elevated in osteoarthritis.Molecular Descriptors in Modelling the Tumour Necrosis Factor-α Converting Enzyme Inhibition Activity of Novel Tartrate-Based Analogues.Metalloproteinase and inhibitor expression profiling of resorbing cartilage reveals pro-collagenase activation as a critical step for collagenolysis.Targeted Fluoro Positioning for the Discovery of a Potent and Highly Selective Matrix Metalloproteinase Inhibitor Probing the S1' site for the identification of non-zinc-binding MMP-2 inhibitors.Characterization of fibrodysplasia in the dog following inhibition of metalloproteinases.

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P2860

Metalloproteinases: their role in arthritis and potential as therapeutic targets.

http://www.wikidata.org/entity/Q35056019

description

2003 nî lūn-bûn

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2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2003 թվականի փետրվարին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

Metalloproteinases: their role in arthritis and potential as therapeutic targets.

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Metalloproteinases: their role in arthritis and potential as therapeutic targets.

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Metalloproteinases: their role in arthritis and potential as therapeutic targets.

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Metalloproteinases: their role in arthritis and potential as therapeutic targets.

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Metalloproteinases: their role in arthritis and potential as therapeutic targets.

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Expert Opinion on Therapeutic Targets

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Metalloproteinases: their role in arthritis and potential as therapeutic targets.

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Andrew E Parker

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Ian M Clark

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P2860

Purification and cloning of aggrecanase-1: a member of the ADAMTS family of proteins

Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family

Sites of aggrecan cleavage by recombinant human aggrecanase-1 (ADAMTS-4)

Procollagen II amino propeptide processing by ADAMTS-3. Insights on dermatosparaxis

Structure of von Willebrand factor-cleaving protease (ADAMTS13), a metalloprotease involved in thrombotic thrombocytopenic purpura

Biochemical characterization of human collagenase-3

Crystal structure of the catalytic domain of human tumor necrosis factor-alpha-converting enzyme

Transcriptional regulation of collagenase (MMP-1, MMP-13) genes in arthritis: integration of complex signaling pathways for the recruitment of gene-specific transcription factors.

A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells

Tissue inhibitors of metalloproteinases: evolution, structure and function

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