Efficient use of a small genome to generate antigenic diversity in tick-borne ehrlichial pathogens.
about
Complete genome sequencing of Anaplasma marginale reveals that the surface is skewed to two superfamilies of outer membrane proteinsTropheryma whipplei Twist: a human pathogenic Actinobacteria with a reduced genomeRestricted changes in major surface protein-2 (msp2) transcription after prolonged in vitro passage of Anaplasma phagocytophilumEvolution of parasitism along convergent lines: from ecology to genomicsExpression patterns of Anaplasma marginale Msp2 variants change in response to growth in cattle, and tick cells versus mammalian cellsAssociation of Anaplasma marginale strain superinfection with infection prevalence within tropical regionsComputational resources in infectious disease: limitations and challengesStructural Basis for Recombinatorial Permissiveness in the Generation of Anaplasma marginale Msp2 Antigenic VariantsIdentification of a novel Anaplasma marginale appendage-associated protein that localizes with actin filaments during intraerythrocytic infectionGenetic variability and stability of Anaplasma phagocytophila msp2 (p44).Conservation in the face of diversity: multistrain analysis of an intracellular bacteriumVariant-specific and diminishing immune responses towards the highly variable MSP2(P44) outer membrane protein of Anaplasma phagocytophilum during persistent infection in lambs.Anaplasma marginale type IV secretion system proteins VirB2, VirB7, VirB11, and VirD4 are immunogenic components of a protective bacterial membrane vaccine.Phylogenomics reveals a diverse Rickettsiales type IV secretion system.Association of pathogen strain-specific gene transcription and transmission efficiency phenotype of Anaplasma marginale.The immunization-induced antibody response to the Anaplasma marginale major surface protein 2 and its association with protective immunity.Establishment of cloned Anaplasma phagocytophilum and analysis of p44 gene conversion within an infected horse and infected SCID mice.Analysis of sequences and loci of p44 homologs expressed by Anaplasma phagocytophila in acutely infected patients.A single Ala139-to-Glu substitution in the Renibacterium salmoninarum virulence-associated protein p57 results in antigenic variation and is associated with enhanced p57 binding to chinook salmon leukocytes.Specific expression of Anaplasma marginale major surface protein 2 salivary gland variants occurs in the midgut and is an early event during tick transmission.Transcript heterogeneity of the p44 multigene family in a human granulocytic ehrlichiosis agent transmitted by ticksMajor histocompatibility complex class II DR-restricted memory CD4(+) T lymphocytes recognize conserved immunodominant epitopes of Anaplasma marginale major surface protein 1a.Focusing homologous recombination: pilin antigenic variation in the pathogenic NeisseriaSubdominant antigens in bacterial vaccines: AM779 is subdominant in the Anaplasma marginale outer membrane vaccine but does not associate with protective immunity.Anaplasma marginale infection with persistent high-load bacteremia induces a dysfunctional memory CD4+ T lymphocyte response but sustained high IgG titersAnalysis of involvement of the RecF pathway in p44 recombination in Anaplasma phagocytophilum and in Escherichia coli by using a plasmid carrying the p44 expression and p44 donor loci.Anaplasma marginale superinfection attributable to pathogen strains with distinct genomic backgrounds.DNA polymorphism in the beta-Esterase gene cluster of Drosophila melanogaster.Analysis of the Anaplasma marginale major surface protein 1 complex protein composition by tandem mass spectrometry.Identification of Anaplasma marginale outer membrane protein antigens conserved between A. marginale sensu stricto strains and the live A. marginale subsp. centrale vaccine.Anaplasma phagocytophilum has a functional msp2 gene that is distinct from p44Sequence analysis of p44 homologs expressed by Anaplasma phagocytophilum in infected ticks feeding on naive hosts and in mice infected by tick attachment.Antigens and alternatives for control of Anaplasma marginale infection in cattle.'Nothing is permanent but change'- antigenic variation in persistent bacterial pathogensMechanisms of variable p44 expression by Anaplasma phagocytophilumPrimary Structural Variation in Anaplasma marginale Msp2 Efficiently Generates Immune Escape Variants.Expansion of variant diversity associated with a high prevalence of pathogen strain superinfection under conditions of natural transmission.Mycoplasma genitalium: an efficient strategy to generate genetic variation from a minimal genome.Genomic and proteomic approaches to vaccine candidate identification for Anaplasma marginale.Antigenic Variation in Bacterial Pathogens.
P2860
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P2860
Efficient use of a small genome to generate antigenic diversity in tick-borne ehrlichial pathogens.
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Efficient use of a small genom ...... ck-borne ehrlichial pathogens.
@ast
Efficient use of a small genom ...... ck-borne ehrlichial pathogens.
@en
type
label
Efficient use of a small genom ...... ck-borne ehrlichial pathogens.
@ast
Efficient use of a small genom ...... ck-borne ehrlichial pathogens.
@en
prefLabel
Efficient use of a small genom ...... ck-borne ehrlichial pathogens.
@ast
Efficient use of a small genom ...... ck-borne ehrlichial pathogens.
@en
P2093
P2860
P356
P1476
Efficient use of a small genom ...... ck-borne ehrlichial pathogens.
@en
P2093
D P Knowles
G H Palmer
K A Brayton
T C McGuire
P2860
P304
P356
10.1073/PNAS.071056298
P407
P577
2001-03-01T00:00:00Z