Mode of action human relevance (species concordance) framework: Evolution of the Bradford Hill considerations and comparative analysis of weight of evidence.
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Exposure to Mixtures of Metals and Neurodevelopmental Outcomes: A Multidisciplinary Review Using an Adverse Outcome Pathway FrameworkComparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in drinking waterPutative adverse outcome pathways relevant to neurotoxicityDeveloping and applying the adverse outcome pathway concept for understanding and predicting neurotoxicityApplication of benchmark dose modeling to protein expression data in the development and analysis of mode of action/adverse outcome pathways for testicular toxicity.Systems Toxicology: Real World Applications and Opportunities.Glyphosate toxicity and carcinogenicity: a review of the scientific basis of the European Union assessment and its differences with IARC.International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposesKey Elements for Judging the Quality of a Risk Assessment.The use of mode of action information in risk assessment: quantitative key events/dose-response framework for modeling the dose-response for key events.Integrating toxicogenomics into human health risk assessment: lessons learned from the benzo[a]pyrene case study.Contribution of new technologies to characterization and prediction of adverse effects.Risk assessments for chronic exposure of children and prospective parents to ethylbenzene (CAS No. 100-41-4).Evolution of chemical-specific adjustment factors (CSAF) based on recent international experience; increasing utility and facilitating regulatory acceptance.Ecdysone Receptor Agonism Leading to Lethal Molting Disruption in Arthropods: Review and Adverse Outcome Pathway Development.Cigarette Filter Ventilation and its Relationship to Increasing Rates of Lung Adenocarcinoma.Dose and temporal evaluation of ethylene oxide-induced mutagenicity in the lungs of male big blue mice following inhalation exposure to carcinogenic concentrations.Adverse outcome pathway development from protein alkylation to liver fibrosis.Challenges in assigning endocrine-specific modes of action: Recommendations for researchers and regulators.Adverse outcome pathways: Application to enhance mechanistic understanding of neurotoxicity.Evaluation of neural reflex activation as a mode of action for the acute respiratory effects of ozone.Evaluating the MoA/human relevance framework for F-344 rat liver epithelioid granulomas with mineral oil hydrocarbons.Coverage of endangered species in environmental risk assessments at EFSAGuidance on the assessment of the biological relevance of data in scientific assessmentsGuidance on the use of the weight of evidence approach in scientific assessmentsBenchmark dose analyses of multiple genetic toxicity endpoints permit robust, cross-tissue comparisons of MutaMouse responses to orally delivered benzo[a]pyrene.Changes in the metabolome and microRNA levels in biological fluids might represent biomarkers of neurotoxicity: A trimethyltin study.Adverse outcome pathways: a concise introduction for toxicologists.Derivation of a no-significant-risk-level for tetrabromobisphenol A based on a threshold non-mutagenic cancer mode of action.An integrative test strategy for cancer hazard identification.
P2860
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P2860
Mode of action human relevance (species concordance) framework: Evolution of the Bradford Hill considerations and comparative analysis of weight of evidence.
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Mode of action human relevance ...... nalysis of weight of evidence.
@ast
Mode of action human relevance ...... nalysis of weight of evidence.
@en
type
label
Mode of action human relevance ...... nalysis of weight of evidence.
@ast
Mode of action human relevance ...... nalysis of weight of evidence.
@en
prefLabel
Mode of action human relevance ...... nalysis of weight of evidence.
@ast
Mode of action human relevance ...... nalysis of weight of evidence.
@en
P2093
P2860
P356
P1476
Mode of action human relevance ...... nalysis of weight of evidence.
@en
P2093
Ammie N Bachman
Christine M Palermo
M E Bette Meek
R Jeffrey Lewis
P2860
P304
P356
10.1002/JAT.2984
P407
P577
2014-02-10T00:00:00Z
2014-06-01T00:00:00Z