The ectodomain of the Toll-like receptor 4 prevents constitutive receptor activation.
about
Toll-like receptor 3 transmembrane domain is able to perform various homotypic interactions: an NMR structural studyCytokine Spatzle binds to the Drosophila immunoreceptor Toll with a neurotrophin-like specificity and couples receptor activationIsolated Toll-like receptor transmembrane domains are capable of oligomerizationA novel pathway for human endothelial cell activation by antiphospholipid/anti-β2 glycoprotein I antibodies.Modular extracellular sensor architecture for engineering mammalian cell-based devices.Activation of lymphoma-associated MyD88 mutations via allostery-induced TIR-domain oligomerization.MD-2 determinants of nickel and cobalt-mediated activation of human TLR4.Contributions of unique intracellular domains to switchlike biosensing by Toll-like receptor 4.NMR studies of hexaacylated endotoxin bound to wild-type and F126A mutant MD-2 and MD-2·TLR4 ectodomain complexes.Toll/interleukin-1 receptor domain dimers as the platform for activation and enhanced inhibition of Toll-like receptor signaling.The COP II adaptor protein TMED7 is required to initiate and mediate the delivery of TLR4 to the plasma membrane.Suppression of TLR signaling by targeting TIR domain-containing proteinsDrugging Membrane Protein Interactions.SARM1-specific motifs in the TIR domain enable NAD+ loss and regulate injury-induced SARM1 activation.CD14 mediates binding of high doses of LPS but is dispensable for TNF-α productionReviewing and identifying amino acids of human, murine, canine and equine TLR4 / MD-2 receptor complexes conferring endotoxic innate immunity activation by LPS/lipid A, or antagonistic effects by Eritoran, in contrast to species-dependent modulationSpatial structure of TLR4 transmembrane domain in bicelles provides the insight into the receptor activation mechanism.Toll-like receptors and their role in persistent pain.
P2860
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P2860
The ectodomain of the Toll-like receptor 4 prevents constitutive receptor activation.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
The ectodomain of the Toll-like receptor 4 prevents constitutive receptor activation.
@ast
The ectodomain of the Toll-like receptor 4 prevents constitutive receptor activation.
@en
type
label
The ectodomain of the Toll-like receptor 4 prevents constitutive receptor activation.
@ast
The ectodomain of the Toll-like receptor 4 prevents constitutive receptor activation.
@en
prefLabel
The ectodomain of the Toll-like receptor 4 prevents constitutive receptor activation.
@ast
The ectodomain of the Toll-like receptor 4 prevents constitutive receptor activation.
@en
P2860
P356
P1476
The ectodomain of the Toll-like receptor 4 prevents constitutive receptor activation.
@en
P2093
Gabriela Panter
Roman Jerala
P2860
P304
23334-23344
P356
10.1074/JBC.M110.205419
P407
P577
2011-05-04T00:00:00Z