Ligand binding domain mutations of the glucocorticoid receptor selectively modify the effects with, but not binding of, cofactors.
about
RSUME enhances glucocorticoid receptor SUMOylation and transcriptional activityPA1 protein, a new competitive decelerator acting at more than one step to impede glucocorticoid receptor-mediated transactivationThe road less traveled: new views of steroid receptor action from the path of dose-response curves.Separate regions of glucocorticoid receptor, coactivator TIF2, and comodulator STAMP modify different parameters of glucocorticoid-mediated gene induction.Kinetically Defined Mechanisms and Positions of Action of Two New Modulators of Glucocorticoid Receptor-regulated Gene Induction.Identification of location and kinetically defined mechanism of cofactors and reporter genes in the cascade of steroid-regulated transactivation.Binding of the N-terminal region of coactivator TIF2 to the intrinsically disordered AF1 domain of the glucocorticoid receptor is accompanied by conformational reorganizationsThe glucocorticoid receptor dimer interface allosterically transmits sequence-specific DNA signals.A conserved protein motif is required for full modulatory activity of negative elongation factor subunits NELF-A and NELF-B in modifying glucocorticoid receptor-regulated gene induction properties.Minireview: dynamic structures of nuclear hormone receptors: new promises and challenges.Theory of partial agonist activity of steroid hormones.
P2860
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P2860
Ligand binding domain mutations of the glucocorticoid receptor selectively modify the effects with, but not binding of, cofactors.
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Ligand binding domain mutation ...... but not binding of, cofactors.
@ast
Ligand binding domain mutation ...... but not binding of, cofactors.
@en
type
label
Ligand binding domain mutation ...... but not binding of, cofactors.
@ast
Ligand binding domain mutation ...... but not binding of, cofactors.
@en
prefLabel
Ligand binding domain mutation ...... but not binding of, cofactors.
@ast
Ligand binding domain mutation ...... but not binding of, cofactors.
@en
P2860
P356
P1433
P1476
Ligand binding domain mutation ...... but not binding of, cofactors.
@en
P2093
Geun-Shik Lee
S Stoney Simons
P2860
P304
P356
10.1021/BI101792D
P407
P577
2010-12-30T00:00:00Z