Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells.
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Angiopoietin 2 is a partial agonist/antagonist of Tie2 signaling in the endotheliumAngiopoietin-Tie signalling in the cardiovascular and lymphatic systemsAngiopoietin-2 is a direct transcriptional target of TAL1, LYL1 and LMO2 in endothelial cellsSustained inflammation after pericyte depletion induces irreversible blood-retina barrier breakdownNormalization of the vasculature for treatment of cancer and other diseases.Angiopoietin-2 differentially regulates angiogenesis through TIE2 and integrin signaling.Tie1 controls angiopoietin function in vascular remodeling and inflammation.A novel angiopoietin-2 selective fully human antibody with potent anti-tumoral and anti-angiogenic efficacy and superior side effect profile compared to Pan-Angiopoietin-1/-2 inhibitors.Differential response of lymphatic, venous and arterial endothelial cells to angiopoietin-1 and angiopoietin-2.Circulating angiopoietin 2 correlates with mortality in a surgical population with acute lung injury/adult respiratory distress syndromeAngiopoietin-1 treatment reduces inflammation but does not prevent ventilator-induced lung injury.Angiogenesis-related factors in skeletal muscles of COPD patients: roles of angiopoietin-2.Tie2 in tumor endothelial signaling and survival: implications for antiangiogenic therapy.Angiopoietin-2 confers Atheroprotection in apoE-/- mice by inhibiting LDL oxidation via nitric oxide.Autocrine role of angiopoietins during megakaryocytic differentiationAngiopoietin-2-driven vascular remodeling in airway inflammationHigh level expression of angiopoietin-2 in human abscesses.Ischemia-induced exocytosis of Weibel-Palade bodies mobilizes stem cells.Angiopoietin-2 is critical for cytokine-induced vascular leakageSignaling via PI3K/FOXO1A pathway modulates formation and survival of human embryonic stem cell-derived endothelial cells.An eosinophil immune response characterizes the inflammatory skin disease observed in Tie-2 transgenic mice.Multitargeting strategy using lenvatinib and golvatinib: maximizing anti-angiogenesis activity in a preclinical cancer model.Endothelial progenitor cells (EPC) in sepsis with acute renal dysfunction (ARD).Angiopoeitin-2 modulates Survivin expression in OxLDL-induced endothelial cell apoptosis.Effects of angiopoietin-2-blocking antibody on endothelial cell-cell junctions and lung metastasisTumor-targeted TNFα stabilizes tumor vessels and enhances active immunotherapy.Why targeted therapy hasn't worked in advanced cancer.Impaired function of the Tie-2 receptor contributes to vascular leakage and lethality in anthrax.The complex role of angiopoietin-2 in the angiopoietin-tie signaling pathway.Prazosin Can Prevent Glucocorticoid Mediated Capillary Rarefaction.Evidence for proangiogenic cellular and humoral systemic response in patients with acute onset of spinal cord injury.MicroRNA-150 Suppression of Angiopoetin-2 Generation and Signaling Is Crucial for Resolving Vascular InjuryAngiopoietin-2 is vasoprotective in the acute phase of cerebral ischemiaEndovascular biopsy: Strategy for analyzing gene expression profiles of individual endothelial cells obtained from human vessels(✩).VEGF-targeted cancer therapy strategies: current progress, hurdles and future prospects.Dual inhibition of Ang-2 and VEGF receptors normalizes tumor vasculature and prolongs survival in glioblastoma by altering macrophages.Defective remodeling and maturation of the lymphatic vasculature in Angiopoietin-2 deficient mice.Dehydroepiandrosterone stimulates phosphorylation of FoxO1 in vascular endothelial cells via phosphatidylinositol 3-kinase- and protein kinase A-dependent signaling pathways to regulate ET-1 synthesis and secretion.Circulating angiopoietin-1 and angiopoietin-2 in critically ill patients: development and clinical application of two new immunoassaysForkhead transcription factors and cardiovascular biology
P2860
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P2860
Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells.
description
2006 nî lūn-bûn
@nan
2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells.
@ast
Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells.
@en
type
label
Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells.
@ast
Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells.
@en
prefLabel
Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells.
@ast
Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells.
@en
P2093
P2860
P356
P1476
Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells.
@en
P2093
Christopher Daly
Donald M McDonald
Elena Burova
Elizabeth Pasnikowski
Ella Ioffe
Gavin Thurston
George D Yancopoulos
James P Fandl
Jennifer Griffiths
John S Rudge
P2860
P304
15491-15496
P356
10.1073/PNAS.0607538103
P407
P577
2006-10-09T00:00:00Z