Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells. - Wikidata - awgldk - TriplyDB

Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells.

Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells.

http://www.wikidata.org/entity/Q35070344

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Angiopoietin 2 is a partial agonist/antagonist of Tie2 signaling in the endothelium Angiopoietin-Tie signalling in the cardiovascular and lymphatic systems Angiopoietin-2 is a direct transcriptional target of TAL1, LYL1 and LMO2 in endothelial cells Sustained inflammation after pericyte depletion induces irreversible blood-retina barrier breakdown Normalization of the vasculature for treatment of cancer and other diseases.Angiopoietin-2 differentially regulates angiogenesis through TIE2 and integrin signaling.Tie1 controls angiopoietin function in vascular remodeling and inflammation.A novel angiopoietin-2 selective fully human antibody with potent anti-tumoral and anti-angiogenic efficacy and superior side effect profile compared to Pan-Angiopoietin-1/-2 inhibitors.Differential response of lymphatic, venous and arterial endothelial cells to angiopoietin-1 and angiopoietin-2.Circulating angiopoietin 2 correlates with mortality in a surgical population with acute lung injury/adult respiratory distress syndrome Angiopoietin-1 treatment reduces inflammation but does not prevent ventilator-induced lung injury.Angiogenesis-related factors in skeletal muscles of COPD patients: roles of angiopoietin-2.Tie2 in tumor endothelial signaling and survival: implications for antiangiogenic therapy.Angiopoietin-2 confers Atheroprotection in apoE-/- mice by inhibiting LDL oxidation via nitric oxide.Autocrine role of angiopoietins during megakaryocytic differentiation Angiopoietin-2-driven vascular remodeling in airway inflammation High level expression of angiopoietin-2 in human abscesses.Ischemia-induced exocytosis of Weibel-Palade bodies mobilizes stem cells.Angiopoietin-2 is critical for cytokine-induced vascular leakage Signaling via PI3K/FOXO1A pathway modulates formation and survival of human embryonic stem cell-derived endothelial cells.An eosinophil immune response characterizes the inflammatory skin disease observed in Tie-2 transgenic mice.Multitargeting strategy using lenvatinib and golvatinib: maximizing anti-angiogenesis activity in a preclinical cancer model.Endothelial progenitor cells (EPC) in sepsis with acute renal dysfunction (ARD).Angiopoeitin-2 modulates Survivin expression in OxLDL-induced endothelial cell apoptosis.Effects of angiopoietin-2-blocking antibody on endothelial cell-cell junctions and lung metastasis Tumor-targeted TNFα stabilizes tumor vessels and enhances active immunotherapy.Why targeted therapy hasn't worked in advanced cancer.Impaired function of the Tie-2 receptor contributes to vascular leakage and lethality in anthrax.The complex role of angiopoietin-2 in the angiopoietin-tie signaling pathway.Prazosin Can Prevent Glucocorticoid Mediated Capillary Rarefaction.Evidence for proangiogenic cellular and humoral systemic response in patients with acute onset of spinal cord injury.MicroRNA-150 Suppression of Angiopoetin-2 Generation and Signaling Is Crucial for Resolving Vascular Injury Angiopoietin-2 is vasoprotective in the acute phase of cerebral ischemia Endovascular biopsy: Strategy for analyzing gene expression profiles of individual endothelial cells obtained from human vessels(✩).VEGF-targeted cancer therapy strategies: current progress, hurdles and future prospects.Dual inhibition of Ang-2 and VEGF receptors normalizes tumor vasculature and prolongs survival in glioblastoma by altering macrophages.Defective remodeling and maturation of the lymphatic vasculature in Angiopoietin-2 deficient mice.Dehydroepiandrosterone stimulates phosphorylation of FoxO1 in vascular endothelial cells via phosphatidylinositol 3-kinase- and protein kinase A-dependent signaling pathways to regulate ET-1 synthesis and secretion.Circulating angiopoietin-1 and angiopoietin-2 in critically ill patients: development and clinical application of two new immunoassays Forkhead transcription factors and cardiovascular biology

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Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells.

http://www.wikidata.org/entity/Q35070344

description

2006 nî lūn-bûn

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2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells.

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Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells.

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Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells.

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Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells.

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Proceedings of the National Academy of Sciences of the United States of America

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Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells.

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Christopher Daly

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Donald M McDonald

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Elena Burova

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Elizabeth Pasnikowski

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Ella Ioffe

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Gavin Thurston

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George D Yancopoulos

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James P Fandl

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Jennifer Griffiths

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John S Rudge

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P2860

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

Multiple angiopoietin recombinant proteins activate the Tie1 receptor tyrosine kinase and promote its interaction with Tie2

Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning

Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis

Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation

Excess circulating angiopoietin-2 may contribute to pulmonary vascular leak in sepsis in humans

The Akt-regulated forkhead transcription factor FOXO3a controls endothelial cell viability through modulation of the caspase-8 inhibitor FLIP

Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis

Abnormal angiogenesis in Foxo1 (Fkhr)-deficient mice

Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification

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