β-cell loss and β-cell apoptosis in human type 2 diabetes are related to islet amyloid deposition. - Wikidata - awgldk - TriplyDB

β-cell loss and β-cell apoptosis in human type 2 diabetes are related to islet amyloid deposition.

β-cell loss and β-cell apoptosis in human type 2 diabetes are related to islet amyloid deposition.

http://www.wikidata.org/entity/Q35070534

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Apoptosis in pancreatic β-islet cells in Type 2 diabetes Dynamic pathology of islet endocrine cells in type 2 diabetes: β-Cell growth, death, regeneration and their clinical implications Report from IPITA-TTS Opinion Leaders Meeting on the Future of β-Cell Replacement Hyaluronan: A Mediator of Islet Dysfunction and Destruction in Diabetes?Alpha-, Delta- and PP-cells: Are They the Architectural Cornerstones of Islet Structure and Co-ordination?Amylin at the interface between metabolic and neurodegenerative disorders β-cell dysfunction: Its critical role in prevention and management of type 2 diabetes.Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future.Islet amyloid formation is an important determinant for inducing islet inflammation in high-fat-fed human IAPP transgenic mice.The human serum protein C4b-binding protein inhibits pancreatic IAPP-induced inflammasome activation.Neuroinflammation and neurologic deficits in diabetes linked to brain accumulation of amylin.Islet amyloid with macrophage migration correlates with augmented β-cell deficits in type 2 diabetic patients Factors associated with beta-cell dysfunction in type 2 diabetes: the BETADECLINE study.Characterisation of age-dependent beta cell dynamics in the male db/db mice.cJUN N-terminal kinase (JNK) activation mediates islet amyloid-induced beta cell apoptosis in cultured human islet amyloid polypeptide transgenic mouse islets.Insulin augmentation of glucose-stimulated insulin secretion is impaired in insulin-resistant humans.Type 2 diabetes as a protein misfolding disease.Targeting metabolic disorders by natural products.Accumulation of intrahepatic islet amyloid in a nonhuman primate transplant model Islet amyloid polypeptide triggers limited complement activation and binds complement inhibitor C4b-binding protein, which enhances fibril formation.Suppression of pancreatic beta cell apoptosis by Danzhi Jiangtang capsule contributes to the attenuation of type 1 diabetes in rats Determination of Optimal Sample Size for Quantification of β-Cell Area, Amyloid Area and β-Cell Apoptosis in Isolated Islets Overall sulfation of heparan sulfate from pancreatic islet β-TC3 cells increases maximal fibril formation but does not determine binding to the amyloidogenic peptide islet amyloid polypeptide Matrix Metalloproteinase-9 Protects Islets from Amyloid-induced Toxicity Changes in pancreatic histology, insulin secretion and oxidative status in diabetic rats following treatment with Ficus deltoidea and vitexin.Hyaluronan and hyaluronan binding proteins are normal components of mouse pancreatic islets and are differentially expressed by islet endocrine cell types Quantifying β-cells in health and disease: the past, the present, and the need.β-Cell failure in type 2 diabetes: a case of asking too much of too few?Matrix metalloproteinase-9 reduces islet amyloid formation by degrading islet amyloid polypeptide Pancreatic β-Cell Membrane Fluidity and Toxicity Induced by Human Islet Amyloid Polypeptide Species.Interactions between genetic background, insulin resistance and β-cell function.Degradation of islet amyloid polypeptide by neprilysin.Incretin therapy and islet pathology: a time for caution.Resveratrol prevents β-cell dedifferentiation in nonhuman primates given a high-fat/high-sugar diet.One year of sitagliptin treatment protects against islet amyloid-associated β-cell loss and does not induce pancreatitis or pancreatic neoplasia in mice.Impact of obesity severity and duration on pancreatic β- and α-cell dynamics in normoglycemic non-human primates.Atomic structures of fibrillar segments of hIAPP suggest tightly mated β-sheets are important for cytotoxicity.Linking metabolic abnormalities to apoptotic pathways in Beta cells in type 2 diabetes Amyloid in the islets of Langerhans: thoughts and some historical aspects.Localized amyloids important in diseases outside the brain--lessons from the islets of Langerhans and the thoracic aorta.

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P2860

β-cell loss and β-cell apoptosis in human type 2 diabetes are related to islet amyloid deposition.

http://www.wikidata.org/entity/Q35070534

description

2011 nî lūn-bûn

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2011 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2011 թվականի հունիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

β-cell loss and β-cell apoptos ...... d to islet amyloid deposition.

@ast

β-cell loss and β-cell apoptos ...... d to islet amyloid deposition.

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type

label

β-cell loss and β-cell apoptos ...... d to islet amyloid deposition.

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β-cell loss and β-cell apoptos ...... d to islet amyloid deposition.

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prefLabel

β-cell loss and β-cell apoptos ...... d to islet amyloid deposition.

@ast

β-cell loss and β-cell apoptos ...... d to islet amyloid deposition.

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J.AJPATH.2011.02.036

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The American Journal of Pathology

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β-cell loss and β-cell apoptos ...... d to islet amyloid deposition.

@en

P2093

Catherine A Jurgens

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Corinne L Fligner

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Darcy B Carr

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Gunilla T Westermark

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Jayalakshmi Udayasankar

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Mirna N Toukatly

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Per Westermark

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Rebecca L Hull

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Sakeneh Zraika

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Shoba L Subramanian

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P2860

Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus

Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells

Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients

Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

Evidence for proteotoxicity in beta cells in type 2 diabetes: toxic islet amyloid polypeptide oligomers form intracellularly in the secretory pathway.

The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes.

Hyalinization of the islets of Langerhans in nondiabetic individuals

Small interfering RNA-mediated suppression of proislet amyloid polypeptide expression inhibits islet amyloid formation and enhances survival of human islets in culture.

Oxidative stress is induced by islet amyloid formation and time-dependently mediates amyloid-induced beta cell apoptosis.

Pancreatic islet amyloidosis, beta-cell apoptosis, and alpha-cell proliferation are determinants of islet remodeling in type-2 diabetic baboons.

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2632-2640

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10.1016/J.AJPATH.2011.02.036

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6

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178

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Kathryn Aston-Mourney

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2011-06-01T00:00:00Z

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51191684

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21641386

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type-2 diabetes

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3123989

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