Podocytes require the engagement of cell surface heparan sulfate proteoglycans for adhesion to extracellular matrices.
about
The glomerular basement membrane as a model system to study the bioactivity of heparan sulfate glycosaminoglycans.Podocyte-specific deletion of NDST1, a key enzyme in the sulfation of heparan sulfate glycosaminoglycans, leads to abnormalities in podocyte organization in vivo.Nef interaction with actin compromises human podocyte actin cytoskeletal integrityN-sulfation of heparan sulfate is critical for syndecan-4-mediated podocyte cell-matrix interactions.The proteoglycan syndecan 4 regulates transient receptor potential canonical 6 channels via RhoA/Rho-associated protein kinase signaling.Cell-matrix adhesion of podocytes in physiology and disease.The importance of podocyte adhesion for a healthy glomerulus.Podocyte-actin dynamics in health and disease.Rethinking glomerular basement membrane thickening in diabetic nephropathy: adaptive or pathogenic?Glomerular basement membrane heparan sulfate in health and disease: A regulator of local complement activation.Synaptopodin is regulated by aromatase activity.Glucocorticoid therapy regulates podocyte motility by inhibition of Rac1The podocyte and the proteoglycan.Serum with phospholipase A2 receptor autoantibodies interferes with podocyte adhesion to collagen.
P2860
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P2860
Podocytes require the engagement of cell surface heparan sulfate proteoglycans for adhesion to extracellular matrices.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Podocytes require the engageme ...... ion to extracellular matrices.
@ast
Podocytes require the engageme ...... ion to extracellular matrices.
@en
type
label
Podocytes require the engageme ...... ion to extracellular matrices.
@ast
Podocytes require the engageme ...... ion to extracellular matrices.
@en
prefLabel
Podocytes require the engageme ...... ion to extracellular matrices.
@ast
Podocytes require the engageme ...... ion to extracellular matrices.
@en
P2093
P2860
P356
P1433
P1476
Podocytes require the engageme ...... sion to extracellular matrices
@en
P2093
A Wayne Orr
Deborah Wassenhove-McCarthy
Lawrence Holzman
Shoujun Chen
Steven Funk
Toin H van Kuppevelt
Yu Yamaguchi
P2860
P2888
P304
P356
10.1038/KI.2010.136
P407
P577
2010-05-12T00:00:00Z