Intravenous administration of retroviral replicating vector, Toca 511, demonstrates therapeutic efficacy in orthotopic immune-competent mouse glioma model - Wikidata - awgldk - TriplyDB

Intravenous administration of retroviral replicating vector, Toca 511, demonstrates therapeutic efficacy in orthotopic immune-competent mouse glioma model

Intravenous administration of retroviral replicating vector, Toca 511, demonstrates therapeutic efficacy in orthotopic immune-competent mouse glioma model

http://www.wikidata.org/entity/Q35077635

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High-grade glioma management and response assessment-recent advances and current challenges Photodynamic therapy enhances the efficacy of gene-directed enzyme prodrug therapy.EXPLORING THE ANTITUMOR EFFECT OF VIRUS IN MALIGNANT GLIOMA Targeting tumor suppressor genes for cancer therapy.Toca 511 gene transfer and treatment with the prodrug, 5-fluorocytosine, promotes durable antitumor immunity in a mouse glioma model.Viral vectors for therapy of neurologic diseases.Gene Delivery in Neuro-Oncology.Retroviral replicating vector-mediated gene therapy achieves long-term control of tumor recurrence and leads to durable anticancer immunity.Toca 511 plus 5-fluorocytosine in combination with lomustine shows chemotoxic and immunotherapeutic activity with no additive toxicity in rodent glioblastoma models.Phase 1 trial of vocimagene amiretrorepvec and 5-fluorocytosine for recurrent high-grade glioma.A Retroviral Replicating Vector Encoding Cytosine Deaminase and 5-FC Induces Immune Memory in Metastatic Colorectal Cancer Models.Viral Vectors in Gene Therapy.Glioblastoma Treatments: An Account of Recent Industrial Developments

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Intravenous administration of retroviral replicating vector, Toca 511, demonstrates therapeutic efficacy in orthotopic immune-competent mouse glioma model

http://www.wikidata.org/entity/Q35077635

description

2015 nî lūn-bûn

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2015 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2015年の論文

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Intravenous administration of ...... e-competent mouse glioma model

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Human Gene Therapy

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Bryan Martin

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Carlos E Ibañez

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Daniel Pertschuk

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Derek Ostertag

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Fernando Lopez Espinoza

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Florence M Hofman

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Harry E Gruber

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Noriyuki Kasahara

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P2860

The gene therapy journey for hemophilia: are we there yet?

Inhibition by uridine but not thymidine of p53-dependent intestinal apoptosis initiated by 5-fluorouracil: evidence for the involvement of RNA perturbation

The resistance of retroviral vectors produced from human cells to serum inactivation in vivo and in vitro is primate species dependent.

Blockade of type I interferon (IFN) production by retroviral replicating vectors and reduced tumor cell responses to IFN likely contribute to tumor selectivity

Phase I/IIa study of intratumoral/intracerebral or intravenous/intracerebral administration of Parvovirus H-1 (ParvOryx) in patients with progressive primary or recurrent glioblastoma multiforme: ParvOryx01 protocol

Single-shot, multicycle suicide gene therapy by replication-competent retrovirus vectors achieves long-term survival benefit in experimental glioma.

Brain tumor eradication and prolonged survival from intratumoral conversion of 5-fluorocytosine to 5-fluorouracil using a nonlytic retroviral replicating vector

Design and selection of Toca 511 for clinical use: modified retroviral replicating vector with improved stability and gene expression.

Gliomas promote immunosuppression through induction of B7-H1 expression in tumor-associated macrophages

Angiogenesis in glioblastoma multiforme: navigating the maze.

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10.1089/HUM.2014.100

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