EHMT2 inhibitor BIX-01294 induces apoptosis through PMAIP1-USP9X-MCL1 axis in human bladder cancer cells - Wikidata - awgldk - TriplyDB

EHMT2 inhibitor BIX-01294 induces apoptosis through PMAIP1-USP9X-MCL1 axis in human bladder cancer cells

EHMT2 inhibitor BIX-01294 induces apoptosis through PMAIP1-USP9X-MCL1 axis in human bladder cancer cells

http://www.wikidata.org/entity/Q35079329

about

G9a Inhibition Induces Autophagic Cell Death via AMPK/mTOR Pathway in Bladder Transitional Cell Carcinoma Histone lysine methyltransferase G9a is a novel epigenetic target for the treatment of hepatocellular carcinoma.Genomic characterization of pediatric T-cell acute lymphoblastic leukemia reveals novel recurrent driver mutations Specific combinations of the chromatin-modifying enzyme modulators significantly attenuate glioblastoma cell proliferation and viability while exerting minimal effect on normal adult stem cells growth.Epigenetic actions of environmental factors and promising drugs for cancer therapy.Targeting Epigenetic Aberrations in Pancreatic Cancer, a New Path to Improve Patient Outcomes?BIX-01294 sensitizes renal cancer Caki cells to TRAIL-induced apoptosis through downregulation of survivin expression and upregulation of DR5 expression.

P2860

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P2860

EHMT2 inhibitor BIX-01294 induces apoptosis through PMAIP1-USP9X-MCL1 axis in human bladder cancer cells

http://www.wikidata.org/entity/Q35079329

description

2015 nî lūn-bûn

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2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2015 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2015年の論文

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2015年論文

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2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

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2015年論文

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2015年论文

@wuu

name

EHMT2 inhibitor BIX-01294 indu ...... in human bladder cancer cells

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EHMT2 inhibitor BIX-01294 indu ...... in human bladder cancer cells

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type

label

EHMT2 inhibitor BIX-01294 indu ...... in human bladder cancer cells

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EHMT2 inhibitor BIX-01294 indu ...... in human bladder cancer cells

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prefLabel

EHMT2 inhibitor BIX-01294 indu ...... in human bladder cancer cells

@ast

EHMT2 inhibitor BIX-01294 indu ...... in human bladder cancer cells

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Cancer Cell International

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EHMT2 inhibitor BIX-01294 indu ...... in human bladder cancer cells

@en

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Jing Cui

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Ling Su

http://www.w3.org/2001/XMLSchema#string

Minli Wei

http://www.w3.org/2001/XMLSchema#string

Wendong Sun

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Xiaonan Su

http://www.w3.org/2001/XMLSchema#string

Xuexi Hao

http://www.w3.org/2001/XMLSchema#string

Yajing Zhang

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P2860

G9a and Glp methylate lysine 373 in the tumor suppressor p53

PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK- and IRE1α-mediated unfolded protein response

The G9a gene in the human major histocompatibility complex encodes a novel protein containing ankyrin-like repeats

A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

Autophagy induced by calcium phosphate precipitates involves endoplasmic reticulum membranes in autophagosome biogenesis

Set domain-containing protein, G9a, is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3

Bax directly induces release of cytochrome c from isolated mitochondria

Mediators of endoplasmic reticulum stress-induced apoptosis

Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase.

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