Acidification of the osteoclastic resorption compartment provides insight into the coupling of bone formation to bone resorption. - Wikidata - awgldk - TriplyDB

Acidification of the osteoclastic resorption compartment provides insight into the coupling of bone formation to bone resorption.

Acidification of the osteoclastic resorption compartment provides insight into the coupling of bone formation to bone resorption.

http://www.wikidata.org/entity/Q35083626

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Differentially expressed genes in autosomal dominant osteopetrosis type II osteoclasts reveal known and novel pathways for osteoclast biology The G215R mutation in the Cl-/H+-antiporter ClC-7 found in ADO II osteopetrosis does not abolish function but causes a severe trafficking defect Dissociation of bone resorption and bone formation in adult mice with a non-functional V-ATPase in osteoclasts leads to increased bone strength Does increased local bone resorption secondary to breast and prostate cancer result in increased cartilage degradation?Optimizing bioavailability of oral administration of small peptides through pharmacokinetic and pharmacodynamic parameters: the effect of water and timing of meal intake on oral delivery of Salmon Calcitonin Investigation of the diurnal variation in bone resorption for optimal drug delivery and efficacy in osteoporosis with oral calcitonin Alterations in osteoclast function and phenotype induced by different inhibitors of bone resorption--implications for osteoclast quality Tenofovir-associated bone density loss.Screening of protein kinase inhibitors identifies PKC inhibitors as inhibitors of osteoclastic acid secretion and bone resorption.Proton pump inhibitors and histamine-2 receptor antagonists are associated with hip fractures among at-risk patients.Aging, human immunodeficiency virus, and bone health.Podosome organization drives osteoclast-mediated bone resorption.Targeting pro-inflammatory cytokines following joint injury: acute intra-articular inhibition of interleukin-1 following knee injury prevents post-traumatic arthritis.Semen Astragali Complanati- and Rhizoma Cibotii-enhanced bone formation in osteoporosis rats.Osteoclasts from patients with autosomal dominant osteopetrosis type I caused by a T253I mutation in low-density lipoprotein receptor-related protein 5 are normal in vitro, but have decreased resorption capacity in vivo A novel assay for analysis of the regulation of the function of human osteoclasts Channel or transporter? The CLC saga continues.Are nonresorbing osteoclasts sources of bone anabolic activity?Deletion of Rac in Mature Osteoclasts Causes Osteopetrosis, an Age-Dependent Change in Osteoclast Number, and a Reduced Number of Osteoblasts In Vivo.Biochemical markers in preclinical models of osteoporosis.Clinical, genetic, and cellular analysis of 49 osteopetrotic patients: implications for diagnosis and treatment.Effects of rabeprazole on bone metabolic disorders in a gastrectomized rat model Painful boney metastases.Osteoclast-secreted CTHRC1 in the coupling of bone resorption to formation Advances in osteoclast biology resulting from the study of osteopetrotic mutations.Therapeutic potentials of naringin on polymethylmethacrylate induced osteoclastogenesis and osteolysis, in vitro and in vivo assessments.Biochemical markers and the FDA Critical Path: how biomarkers may contribute to the understanding of pathophysiology and provide unique and necessary tools for drug development.Osteoclast polarization and orthodontic tooth movement.Which elements are involved in reversible and irreversible cartilage degradation in osteoarthritis?Use of bone turnover markers in clinical osteoporosis assessment in women: current issues and future options.Osteoclast-derived coupling factors in bone remodeling.Novel targets for the prevention of osteoporosis - lessons learned from studies of metabolic bone disorders.Taxonomy of rare genetic metabolic bone disorders.Non-enzymatic glycation of bone collagen modifies osteoclastic activity and differentiation.Biomarkers for Bisphosphonate-Related Osteonecrosis of the Jaw.A novel inhibitory mechanism of nitrogen-containing bisphosphonate on the activity of Cl- extrusion in osteoclasts.Diphyllin, a novel and naturally potent V-ATPase inhibitor, abrogates acidification of the osteoclastic resorption lacunae and bone resorption.Unique uptake and efflux systems of inorganic phosphate in osteoclast-like cells.Cartilage degradation is fully reversible in the presence of aggrecanase but not matrix metalloproteinase activity Preventive effects of kudzu root on bone loss and cartilage degradation in ovariectomized rat

P2860

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P2860

Acidification of the osteoclastic resorption compartment provides insight into the coupling of bone formation to bone resorption.

http://www.wikidata.org/entity/Q35083626

description

2005 nî lūn-bûn

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2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2005 թվականի փետրվարին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

Acidification of the osteoclas ...... formation to bone resorption.

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Acidification of the osteoclas ...... formation to bone resorption.

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type

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Acidification of the osteoclas ...... formation to bone resorption.

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Acidification of the osteoclas ...... formation to bone resorption.

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Acidification of the osteoclas ...... formation to bone resorption.

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Acidification of the osteoclas ...... formation to bone resorption.

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The American Journal of Pathology

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Acidification of the osteoclas ...... e formation to bone resorption

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Claus Christiansen

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Jens Bollerslev

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Jeppe Gram

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Kim Henriksen

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Mette G Sørensen

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Morten A Karsdal

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Morten H Dziegiel

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Palle Christophersen

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Sophie Schaller

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Thomas J Martin

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P2860

Characterization of osteoclasts from patients harboring a G215R mutation in ClC-7 causing autosomal dominant osteopetrosis type II

Loss of the ClC-7 chloride channel leads to osteopetrosis in mice and man

Albers-Schönberg disease (autosomal dominant osteopetrosis, type II) results from mutations in the ClCN7 chloride channel gene

Pycnodysostosis: role and regulation of cathepsin K in osteoclast function and human disease

Genetic regulation of osteoclast development and function

The effects of 2-year treatment with the aminobisphosphonate alendronate on bone metabolism, bone histomorphometry, and bone strength in ovariectomized nonhuman primates.

Human osteopetrosis and other sclerosing disorders: recent genetic developments.

Osteoclastic bone resorption by a polarized vacuolar proton pump.

Discoveries, drugs and skeletal disorders.

Decreased bone turnover and deterioration of bone structure in two cases of pycnodysostosis.

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467-476

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10.1016/S0002-9440(10)62269-9

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2

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Anne-Marie Heegaard

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15681830

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