The Wnt inhibitory factor 1 (WIF1) is targeted in glioblastoma and has a tumor suppressing function potentially by induction of senescence - Wikidata - awgldk - TriplyDB

The Wnt inhibitory factor 1 (WIF1) is targeted in glioblastoma and has a tumor suppressing function potentially by induction of senescence

The Wnt inhibitory factor 1 (WIF1) is targeted in glioblastoma and has a tumor suppressing function potentially by induction of senescence

http://www.wikidata.org/entity/Q35085317

about

Current Understanding on EGFR and Wnt/β-Catenin Signaling in Glioma and Their Possible Crosstalk MiR-92b inhibitor promoted glioma cell apoptosis via targeting DKK3 and blocking the Wnt/beta-catenin signaling pathway Identifying disease-associated pathways in one-phenotype data based on reversal gene expression orderings.Aberrant methylation of NPY, PENK, and WIF1 as a promising marker for blood-based diagnosis of colorectal cancer Chromosome 7 gain and DNA hypermethylation at the HOXA10 locus are associated with expression of a stem cell related HOX-signature in glioblastoma.Wnt pathway in atypical teratoid rhabdoid tumors.DNA fingerprinting of glioma cell lines and considerations on similarity measurements.MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-status Wnt pathway antagonists, SFRP1, SFRP2, SOX17, and PPP2R2B, are methylated in gliomas and SFRP1 methylation predicts shorter survival.Ang-2/VEGF bispecific antibody reprograms macrophages and resident microglia to anti-tumor phenotype and prolongs glioblastoma survival.Identification and characterization of a small-molecule inhibitor of Wnt signaling in glioblastoma cells.β-Catenin Expression Negatively Correlates with WIF1 and Predicts Poor Clinical Outcomes in Patients with Cervical Cancer.Predicting the Remaining Lifespan and Cultivation-Related Loss of Osteogenic Capacity of Bone Marrow Multipotential Stromal Cells Applicable across a Broad Donor Age Range.Presence of an oligodendroglioma-like component in newly diagnosed glioblastoma identifies a pathogenetically heterogeneous subgroup and lacks prognostic value: central pathology review of the EORTC_26981/NCIC_CE.3 trial.The impact of age on oncogenic potential: tumor-initiating cells and the brain microenvironment.Epigenetic pathways and glioblastoma treatment: insights from signaling cascades.Native Oligodendrocytes in Astrocytomas Might Inhibit Tumor Proliferation by WIF1 Expression.Radiation-agent combinations for glioblastoma: challenges in drug development and future considerations.Elucidation of the genetic and epigenetic landscape alterations in RNA binding proteins in glioblastoma.Pharmacologic Wnt Inhibition Reduces Proliferation, Survival, and Clonogenicity of Glioblastoma Cells.DNA methylation in adult diffuse gliomas.Wnt inhibitory factor 1 suppresses cancer stemness and induces cellular senescence.The Process and Regulatory Components of Inflammation in Brain Oncogenesis.Promoter methylation of WNT inhibitory factor-1 and expression pattern of WNT/β-catenin pathway in human astrocytoma: pathologic and prognostic correlations.Epigenetic approach for angiostatic therapy: promising combinations for cancer treatment.Aberrant Wnt signaling: a special focus in CNS diseases.Revealing radiotherapy- and chemoradiation-induced pathway dynamics in glioblastoma by analyzing multiple differential networks.Ubiquitin Specific Peptidase 15 (USP15) suppresses glioblastoma cell growth via stabilization of HECTD1 E3 ligase attenuating WNT pathway activity.The Role of Wnt Signal in Glioblastoma Development and Progression: A Possible New Pharmacological Target for the Therapy of This Tumor.SHH, WNT, and NOTCH pathways in medulloblastoma: when cancer stem cells maintain self-renewal and differentiation properties.REST, not REST4, is a risk factor associated with radiotherapy plus chemotherapy efficacy in glioma.Opposite Interplay Between the Canonical WNT/β-Catenin Pathway and PPAR Gamma: A Potential Therapeutic Target in Gliomas.Sclerostin promotes human dental pulp cells senescence

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The Wnt inhibitory factor 1 (WIF1) is targeted in glioblastoma and has a tumor suppressing function potentially by induction of senescence

http://www.wikidata.org/entity/Q35085317

description

2011 nî lūn-bûn

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2011 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2011 թվականի հունիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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Anastasia Murat

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Anjan Misra

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Annie-Claire Diserens

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Burt Feuerstein

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Davide Sciuscio

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Eugenia Migliavacca

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Eytan Domany

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Irene Vassallo

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Marie-France Hamou

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Mauro Delorenzi

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P2860

A new secreted protein that binds to Wnt proteins and inhibits their activities

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

COSMIC (the Catalogue of Somatic Mutations in Cancer): a resource to investigate acquired mutations in human cancer

An integrated genomic analysis of human glioblastoma multiforme

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

MGMT gene silencing and benefit from temozolomide in glioblastoma.

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

Glycogen synthase kinase-3: properties, functions, and regulation

Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway.

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

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736-747

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10.1093/NEUONC/NOR036

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7

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13

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21642372

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3129269

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