Role of DNA mismatch repair defects in the pathogenesis of human cancer.
about
The histone mark H3K36me3 regulates human DNA mismatch repair through its interaction with MutSαFunctional studies and homology modeling of Msh2-Msh3 predict that mispair recognition involves DNA bending and strand separationCadmium inhibits mismatch repair by blocking the ATPase activity of the MSH2-MSH6 complexMolecular Subtypes and Personalized Therapy in Metastatic Colorectal CancerGut microbiota imbalance and colorectal cancerAdenoid cystic carcinoma: current therapy and potential therapeutic advances based on genomic profilingNew insights and challenges in mismatch repair: getting over the chromatin hurdleEarly-onset colorectal cancer: a separate subset of colorectal cancerEscherichia coli MutS tetramerization domain structure reveals that stable dimers but not tetramers are essential for DNA mismatch repair in vivoSubstrate-induced DNA strand misalignment during catalytic cycling by DNA polymerase λStructures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease FamilySaccharomyces cerevisiae Msh2-Msh3 acts in repair of base-base mispairsModulation of the DNA-binding activity of Saccharomyces cerevisiae MSH2-MSH6 complex by the high-mobility group protein NHP6A, in vitroBiomarkers for immune therapy in colorectal cancer: mismatch-repair deficiency and othersImpact of DNA mismatch repair system alterations on human fertility and related treatmentsNew insights into the mechanism of DNA mismatch repairHereditary Syndromes Manifesting as Endometrial Carcinoma: How Can Pathological Features Aid Risk Assessment?Deficiency of MSH2 expression is associated with clear cell renal cell carcinomaExonuclease 1-dependent and independent mismatch repairATR functions as a gene dosage-dependent tumor suppressor on a mismatch repair-deficient backgroundAlterations of copy number of methylation pattern in mismatch repair genes by methylation specific-multiplex ligation-dependent probe amplification in cases of colon cancerMolecular epidemiology of DNA repair gene polymorphisms and head and neck cancer.Dominant mutations in S. cerevisiae PMS1 identify the Mlh1-Pms1 endonuclease active site and an exonuclease 1-independent mismatch repair pathwayThe Rising Incidence of Younger Patients With Colorectal Cancer: Questions About Screening, Biology, and Treatment.Histone deacetylase 10 regulates DNA mismatch repair and may involve the deacetylation of MutS homolog 2.Efficiency of Base Excision Repair of Oxidative DNA Damage and Its Impact on the Risk of Colorectal Cancer in the Polish PopulationMismatch repair protein hMSH2-hMSH6 recognizes mismatches and forms sliding clamps within a D-loop recombination intermediateGenetic testing strategies in newly diagnosed endometrial cancer patients aimed at reducing morbidity or mortality from lynch syndrome in the index case or her relativesProteolysis of the mismatch repair protein MLH1 by caspase-3 promotes DNA damage-induced apoptosis.Mismatch repair and treatment resistance in ovarian cancer.Untangling the relationships between DNA repair pathways by silencing more than 20 DNA repair genes in human stable clones.Three novel missense germline mutations in different exons of MSH6 gene in Chinese hereditary non-polyposis colorectal cancer families.Decoding the histone code: Role of H3K36me3 in mismatch repair and implications for cancer susceptibility and therapy.DNA polymorphism and risk of esophageal squamous cell carcinoma in a population of North Xinjiang, China.A conserved MutS homolog connector domain interface interacts with MutL homologs.Reconstitution of Saccharomyces cerevisiae DNA polymerase ε-dependent mismatch repair with purified proteins.The Emerging Role of PARP Inhibitors in the Treatment of Epithelial Ovarian Cancer.Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burdenMouse models of colorectal cancer.Saccharomyces cerevisiae Msh2-Msh6 DNA binding kinetics reveal a mechanism of targeting sites for DNA mismatch repair.
P2860
Q24339204-2897EB16-C25E-436B-B260-3DAEBE340C8DQ24619622-287C1C27-3D17-410E-BED1-EB8EBD440EC7Q24798955-577CE959-0D82-470C-88E0-3D98BE93159AQ26747329-3FA97658-CE69-4F41-AC01-6C852AEB255DQ26774708-DE50FF35-93FF-48E2-ACAC-DD7FA1099B2BQ26781643-980A1BE1-738C-4623-8A7F-7AB05AD31E5EQ27011117-B0D55641-041D-4269-9E33-C942E0D18741Q27012841-121E36F2-0364-4366-BAC1-C87C90EF306CQ27644397-92FFD096-A494-46F0-A293-4B29FBB84969Q27650171-8B4B173F-163C-4F85-B8B9-78E525578E5CQ27667527-5B7E29E9-A2A3-4FD7-ACF2-70BE2307400EQ27931230-A32AB480-F3D4-49B2-A6C0-0FE68C90C0CCQ27931842-D819BBB0-AF96-4CA8-9668-1DF5CDB89E49Q28072468-530A0F01-B79C-4DEF-A7F6-D4944DFA6D2BQ28074585-E9EEA561-BD6D-4AD4-BF0A-411CBC007D1EQ28084645-0CCAF3DB-E978-4FEF-807E-8C3034388AB3Q28085485-712C5FBF-9C15-4A63-93F5-7BED69CAB5E2Q28249351-935564CB-1F21-4BA5-BA19-2E8FF5908402Q28261787-B4557EBE-B0C5-47A7-939B-9EA775EF0F9CQ28274709-AD4DE906-A88C-474E-9271-0998C74DD78FQ28298882-A9D24D12-820B-40EB-8C4F-50E5C4339AC7Q28383483-A65581D1-83E2-4FE1-A987-0E24FE5F8B13Q28534756-25FB3425-0D03-4778-B673-3F0337E4D4BCQ30234889-C0951D53-7CEE-454B-93A0-EB9A0E8519EFQ30356611-2BD86BCE-303A-45EB-8293-E68B081912D1Q30396620-879D2220-8375-461D-BDC1-C159F0482C5AQ30569509-D6773A83-B67A-49D8-980B-CEBFB976932EQ31139897-5DBC13A5-0C5C-4844-B28D-17507D3CF830Q33201671-47E7E7EE-6610-40F4-A481-7E7B7F549ABAQ33252378-75A5436B-8464-4342-9DFE-7FC321C096DAQ33283854-F1155D1A-73F1-4BE1-A792-469A6579DCBBQ33298821-EF6EA1A8-A529-4D97-9A4D-F0F6A500F102Q33356760-E9154728-6E51-45B1-9AD2-A516101A9737Q33529216-10E9B09B-4A54-4D6C-946B-F317215DF6F6Q33552273-8A9281A2-E6C6-487C-B665-513DD9114D56Q33556873-39E39088-D27B-47EB-A320-FA82740DBE9CQ33557369-3D313D73-7082-4108-9961-F03214FD8792Q33576170-AD71F3E4-61C7-447E-8E02-25ECBAF10849Q33579734-43A121FB-8686-474C-88C0-596ED51F87D9Q33640393-4A05F98A-9BC1-4130-BEBB-BD577290449A
P2860
Role of DNA mismatch repair defects in the pathogenesis of human cancer.
description
2003 nî lūn-bûn
@nan
2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Role of DNA mismatch repair defects in the pathogenesis of human cancer.
@ast
Role of DNA mismatch repair defects in the pathogenesis of human cancer.
@en
type
label
Role of DNA mismatch repair defects in the pathogenesis of human cancer.
@ast
Role of DNA mismatch repair defects in the pathogenesis of human cancer.
@en
prefLabel
Role of DNA mismatch repair defects in the pathogenesis of human cancer.
@ast
Role of DNA mismatch repair defects in the pathogenesis of human cancer.
@en
P3181
P356
P1476
Role of DNA mismatch repair defects in the pathogenesis of human cancer.
@en
P304
P3181
P356
10.1200/JCO.2003.04.060
P407
P577
2003-03-01T00:00:00Z