Akt2 regulates all Akt isoforms and promotes resistance to hypoxia through induction of miR-21 upon oxygen deprivation. - Wikidata - awgldk - TriplyDB

Akt2 regulates all Akt isoforms and promotes resistance to hypoxia through induction of miR-21 upon oxygen deprivation.

Akt2 regulates all Akt isoforms and promotes resistance to hypoxia through induction of miR-21 upon oxygen deprivation.

http://www.wikidata.org/entity/Q35085751

about

Role of Telomerase in the Cardiovascular System HypoxamiRs and cancer: from biology to targeted therapy OxymiRs in cutaneous development, wound repair and regeneration MicroRNAs: promising new antiangiogenic targets in cancer Current relevance of hypoxia in head and neck cancer MicroRNA-21 promotes Th17 differentiation and mediates experimental autoimmune encephalomyelitis Regulation of Transcription Factors by Reactive Oxygen Species and Nitric Oxide in Vascular Physiology and Pathology.Dormancy of cancer cells with suppression of AKT activity contributes to survival in chronic hypoxia.Atlas of Cancer Signalling Network: a systems biology resource for integrative analysis of cancer data with Google Maps Identification of high-copper-responsive target pathways in Atp7b knockout mouse liver by GSEA on microarray data sets.The expression of the Sprouty 1 protein inversely correlates with growth, proliferation, migration and invasion of ovarian cancer cells The developing story of Sprouty and cancer.Understanding the effects of tobacco smoke on the pathogenesis of aortic aneurysm.δ-opioid receptor activation and microRNA expression of the rat cortex in hypoxia δ-Opioid receptor activation modified microRNA expression in the rat kidney under prolonged hypoxia.Astrocyte elevated gene-1 interacts with Akt isoform 2 to control glioma growth, survival, and pathogenesis.miR-21 in ischemia/reperfusion injury: a double-edged sword?Modulators of the microRNA biogenesis pathway via arrayed lentiviral enabled RNAi screening for drug and biomarker discovery.MicroRNA response to hypoxic stress in soft tissue sarcoma cells: microRNA mediated regulation of HIF3α High-Mobility Group Box 1 Promotes Hepatocellular Carcinoma Progression through miR-21-Mediated Matrix Metalloproteinase Activity Elevated PI3K signaling drives multiple breast cancer subtypes.PPARγ Ligands Attenuate Hypoxia-Induced Proliferation in Human Pulmonary Artery Smooth Muscle Cells through Modulation of MicroRNA-21.Sprouty 1 predicts prognosis in human epithelial ovarian cancer The hypoxia-related microRNA miR-199a-3p displays tumor suppressor functions in ovarian carcinoma.The protein kinase Akt1 regulates the interferon response through phosphorylation of the transcriptional repressor EMSY.DNA damage induces NF-κB-dependent microRNA-21 up-regulation and promotes breast cancer cell invasion.Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization MicroRNA214 Is Associated With Progression of Ulcerative Colitis, and Inhibition Reduces Development of Colitis and Colitis-Associated Cancer in Mice Hypoxia inducible factors regulate the transcription of the sprouty2 gene and expression of the sprouty2 protein Current status and implications of microRNAs in ovarian cancer diagnosis and therapy.The importance of the PI3K/AKT/MTOR pathway in the progression of ovarian cancer.Delayed ischemic preconditioning contributes to renal protection by upregulation of miR-21 Meta-analysis using a novel database, miRStress, reveals miRNAs that are frequently associated with the radiation and hypoxia stress-responses.Targeting ROR1 inhibits epithelial-mesenchymal transition and metastasis.Regulation of microRNA expression and function by nuclear receptor signaling.Hypoxia-regulated microRNAs in human cancer.MicroRNAs play a central role in molecular dysfunctions linking inflammation with cancer.Hypoxia: a master regulator of microRNA biogenesis and activity Ovarian cancer: diagnostic, biological and prognostic aspects.Role of miR‑21 on vascular endothelial cells in the protective effect of renal delayed ischemic preconditioning.

P2860

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P2860

Akt2 regulates all Akt isoforms and promotes resistance to hypoxia through induction of miR-21 upon oxygen deprivation.

http://www.wikidata.org/entity/Q35085751

description

2011 nî lūn-bûn

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2011 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2011 թվականի մայիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Akt2 regulates all Akt isoform ...... iR-21 upon oxygen deprivation.

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Akt2 regulates all Akt isoform ...... iR-21 upon oxygen deprivation.

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type

label

Akt2 regulates all Akt isoform ...... iR-21 upon oxygen deprivation.

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Akt2 regulates all Akt isoform ...... iR-21 upon oxygen deprivation.

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prefLabel

Akt2 regulates all Akt isoform ...... iR-21 upon oxygen deprivation.

@ast

Akt2 regulates all Akt isoform ...... iR-21 upon oxygen deprivation.

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0008-5472.CAN-11-0365

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Cancer Research

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Akt2 regulates all Akt isoform ...... iR-21 upon oxygen deprivation.

@en

P2093

Christos Polytarchou

http://www.w3.org/2001/XMLSchema#string

Dimitrios Iliopoulos

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Filippos Kottakis

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Ioanna Maroulakou

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Kevin Struhl

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Maria Hatziapostolou

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Philip N Tsichlis

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P2860

Rel/NF-kappaB can trigger the Notch signaling pathway by inducing the expression of Jagged1, a ligand for Notch receptors

AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas

Direct regulation of TWIST by HIF-1alpha promotes metastasis

Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways

Nuclear protein CBP is a coactivator for the transcription factor CREB

Understanding the Warburg effect: the metabolic requirements of cell proliferation

An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation

Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta

A microRNA signature of hypoxia

A transforming mutation in the pleckstrin homology domain of AKT1 in cancer

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4720-4731

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scholarly article

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10.1158/0008-5472.CAN-11-0365

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13

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71

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21555366

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3129420

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