Phosphorylation of mutant huntingtin at serine 116 modulates neuronal toxicity.

Phosphorylation of mutant huntingtin at serine 116 modulates neuronal toxicity.

Item
http://www.wikidata.org/entity/Q35088655
The emerging role of the first 17 amino acids of huntingtin in Huntington's diseaseα-Synuclein and nonhuman primate models of Parkinson's diseaseFrom pathways to targets: understanding the mechanisms behind polyglutamine disease.Coupling enrichment methods with proteomics for understanding and treating disease.Post-Translational Modifications (PTMs), Identified on Endogenous Huntingtin, Cluster within Proteolytic Domains between HEAT Repeats.Dysregulation of Corticostriatal Connectivity in Huntington's Disease: A Role for Dopamine ModulationProteins Containing Expanded Polyglutamine Tracts and Neurodegenerative Disease.Targeting TEAD/YAP-transcription-dependent necrosis, TRIAD, ameliorates Huntington's disease pathology.The structural integrity of TDP-43 N-terminus is required for efficient aggregate entrapment and consequent loss of protein function.PRMT5- mediated symmetric arginine dimethylation is attenuated by mutant huntingtin and is impaired in Huntington's disease (HD).Post-translational modifications clustering within proteolytic domains decrease mutant huntingtin toxicity.PPARδ activation by bexarotene promotes neuroprotection by restoring bioenergetic and quality control homeostasis.A comprehensive in silico analysis of huntingtin and its interactome.ATXN2-AS, a gene antisense to ATXN2, is associated with spinocerebellar ataxia type 2 and amyotrophic lateral sclerosis.
P2860

Phosphorylation of mutant huntingtin at serine 116 modulates neuronal toxicity.

Item
http://www.wikidata.org/entity/Q35088655
description
2014 nî lūn-bûn
@nan
2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Phosphorylation of mutant huntingtin at serine 116 modulates neuronal toxicity.
@ast
Phosphorylation of mutant huntingtin at serine 116 modulates neuronal toxicity.
@en
type
label
Phosphorylation of mutant huntingtin at serine 116 modulates neuronal toxicity.
@ast
Phosphorylation of mutant huntingtin at serine 116 modulates neuronal toxicity.
@en
prefLabel
Phosphorylation of mutant huntingtin at serine 116 modulates neuronal toxicity.
@ast
Phosphorylation of mutant huntingtin at serine 116 modulates neuronal toxicity.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921
P932
P356
P1433
P1476
Phosphorylation of mutant huntingtin at serine 116 modulates neuronal toxicity.
@en
P2093
P2860
P304
P31
P356
10.1371/JOURNAL.PONE.0088284
P407
P433
P478
P50
P577
P5875
P698
P921
P932