Chronic amitriptyline treatment attenuates nigrostriatal degeneration and significantly alters trophic support in a rat model of parkinsonism - Wikidata - awgldk - TriplyDB

Chronic amitriptyline treatment attenuates nigrostriatal degeneration and significantly alters trophic support in a rat model of parkinsonism

Chronic amitriptyline treatment attenuates nigrostriatal degeneration and significantly alters trophic support in a rat model of parkinsonism

http://www.wikidata.org/entity/Q35089378

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Tricyclic antidepressant treatment evokes regional changes in neurotrophic factors over time within the intact and degenerating nigrostriatal system.Amitriptyline Activates TrkA to Aid Neuronal Growth and Attenuate Anesthesia-Induced Neurodegeneration in Rat Dorsal Root Ganglion Neurons.A Basal Forebrain Site Coordinates the Modulation of Endocrine and Behavioral Stress Responses via Divergent Neural Pathways.Elevated Hapln2 Expression Contributes to Protein Aggregation and Neurodegeneration in an Animal Model of Parkinson's Disease Loss of dopamine D1 receptors and diminished D1/5 receptor-mediated ERK phosphorylation in the periaqueductal gray after spinal cord lesion.Nortriptyline inhibits aggregation and neurotoxicity of alpha-synuclein by enhancing reconfiguration of the monomeric form.Neuroprotective Effects of Antidepressants via Upregulation of Neurotrophic Factors in the MPTP Model of Parkinson's Disease.

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P2860

Chronic amitriptyline treatment attenuates nigrostriatal degeneration and significantly alters trophic support in a rat model of parkinsonism

http://www.wikidata.org/entity/Q35089378

description

2014 nî lūn-bûn

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2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Chronic amitriptyline treatmen ...... in a rat model of parkinsonism

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Neuropsychopharmacology

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Chronic amitriptyline treatmen ...... in a rat model of parkinsonism

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Brian Daley

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Brian Terpstra

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Caryl E Sortwell

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Joshua J Green

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Katrina L Paumier

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Lalitha Madhavan

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Nastassja M Imus

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Nathan Marckini

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Stephanie L Celano

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Timothy J Collier

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P2860

Amitriptyline is a TrkA and TrkB receptor agonist that promotes TrkA/TrkB heterodimerization and has potent neurotrophic activity

Pharmacological profile of antidepressants and related compounds at human monoamine transporters

Antidepressants reduce neuroinflammatory responses and astroglial alpha-synuclein accumulation in a transgenic mouse model of multiple system atrophy

Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus

Nortriptyline delays disease onset in models of chronic neurodegeneration.

Nonmotor symptoms of Parkinson's disease revealed in an animal model with reduced monoamine storage capacity

Tricyclic antidepressants delay the need for dopaminergic therapy in early Parkinson's disease.

Depression in Parkinson's disease: loss of dopamine and noradrenaline innervation in the limbic system.

Antidepressant acts on astrocytes leading to an increase in the expression of neurotrophic/growth factors: differential regulation of FGF-2 by noradrenaline

Antidepressants and neuroplasticity.

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874-883

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scholarly article

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10.1038/NPP.2014.262

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4

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40

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Kathy Steece-Collier

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2014-09-30T00:00:00Z

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1034625910

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