Catalysis by acetylcholinesterase: evidence that the rate-limiting step for acylation with certain substrates precedes general acid-base catalysis.
about
Catalytic mechanism and energy barriers for butyrylcholinesterase-catalyzed hydrolysis of cocaineCloning and expression of acetylcholinesterase from Electrophorus. Splicing pattern of the 3' exons in vivo and in transfected mammalian cells.Monoclonal anti-idiotypic antibodies as functional internal images of enzyme active sites: production of a catalytic antibody with a cholinesterase activity.Analysis of the reaction of carbachol with acetylcholinesterase using thioflavin T as a coupled fluorescence reporter.On the failure of de novo-designed peptides as biocatalysts.A modular treatment of molecular traffic through the active site of cholinesterase.Properties of water molecules in the active site gorge of acetylcholinesterase from computer simulation.Catalysis by acetylcholinesterase in two-hydronic-reactive states. Integrity of deuterium oxide effects and hydron inventories.Acetylcholinesterase: evidence that sodium ion binding at the anionic site causes inhibition of the second-order hydrolysis of acetylcholine and a decrease of its pKa as well as of deacetylation.Amino acid substitutions of acetylcholinesterase associated with carbofuran resistance in Chilo suppressalis.Acetylcholine modulates cortical synaptic transmission via different muscarinic receptors, as studied with receptor knockout mice.Sensing activity of cholinesterases through a luminescence response of the hexarhenium cluster complex [{Re6S8}(OH)6](4.).Identification of new allosteric sites and modulators of AChE through computational and experimental tools.Site-directed mutagenesis of active-site-related residues in Torpedo acetylcholinesterase Presence of a glutamic acid in the catalytic triad
P2860
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P2860
Catalysis by acetylcholinesterase: evidence that the rate-limiting step for acylation with certain substrates precedes general acid-base catalysis.
description
1975 nî lūn-bûn
@nan
1975 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1975 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1975年の論文
@ja
1975年論文
@yue
1975年論文
@zh-hant
1975年論文
@zh-hk
1975年論文
@zh-mo
1975年論文
@zh-tw
1975年论文
@wuu
name
Catalysis by acetylcholinester ...... s general acid-base catalysis.
@ast
Catalysis by acetylcholinester ...... s general acid-base catalysis.
@en
type
label
Catalysis by acetylcholinester ...... s general acid-base catalysis.
@ast
Catalysis by acetylcholinester ...... s general acid-base catalysis.
@en
prefLabel
Catalysis by acetylcholinester ...... s general acid-base catalysis.
@ast
Catalysis by acetylcholinester ...... s general acid-base catalysis.
@en
P2860
P356
P1476
Catalysis by acetylcholinester ...... s general acid-base catalysis.
@en
P2093
Rosenberry TL
P2860
P304
P356
10.1073/PNAS.72.10.3834
P407
P577
1975-10-01T00:00:00Z