Challenges in CYP2D6 phenotype assignment from genotype data: a critical assessment and call for standardization.
about
Exploring the distribution of genetic markers of pharmacogenomics relevance in Brazilian and Mexican populationsRecent Advances in Application of Pharmacogenomics for BiotherapeuticsLong-Read Single Molecule Real-Time Full Gene Sequencing of Cytochrome P450-2D6.Pharmacogenetics in Jewish populations.Addressing phenoconversion: the Achilles' heel of personalized medicine.SNP genotyping using TaqMan technology: the CYP2D6*17 assay conundrum.Prevalence of the CYP2D6*10 (C100T), *4 (G1846A), and *14 (G1758A) alleles among Iranians of different ethnicities.Detection of an endogenous urinary biomarker associated with CYP2D6 activity using global metabolomicsCYP2D6 Haplotype Determination Using Long Range Allele-Specific Amplification: Resolution of a Complex Genotype and a Discordant Genotype Involving the CYP2D6*59 Allele.In vivo assessment of the metabolic activity of CYP2D6 diplotypes and alleles.Role of Pharmacogenetics in Improving the Safety of Psychiatric Care by Predicting the Potential Risks of Mania in CYP2D6 Poor Metabolizers Diagnosed With Bipolar DisorderPharmacogenetics for Safe Codeine Use in Sickle Cell Disease.PGRNseq: a targeted capture sequencing panel for pharmacogenetic research and implementation.Prediction of CYP2D6 phenotype from genotype across world populationsInterethnic variability of CYP2D6 alleles and of predicted and measured metabolic phenotypes across world populations.The Pharmacogenetics of Tramadol.Atomoxetine pharmacogenetics: associations with pharmacokinetics, treatment response and tolerability.Flexible and Scalable Full-Length CYP2D6 Long Amplicon PacBio Sequencing.Sequencing the CYP2D6 gene: from variant allele discovery to clinical pharmacogenetic testing.High Frequency of CYP2D6 Ultrarapid Metabolizer Genotype in the Finnish Population.Systematic and quantitative assessment of the effect of chronic kidney disease on CYP2D6 and CYP3A4/5.Effects of 22 Novel CYP2D6 Variants Found in the Chinese Population on the Bufuralol and Dextromethorphan Metabolisms In Vitro.Personalized Drug Dosage - Closing the Loop.A Population Pharmacokinetic Analysis of Dextroamphetamine in the Plasma and Hair of Healthy Adults.Improved Prediction of Endoxifen Metabolism by CYP2D6 Genotype in Breast Cancer Patients Treated with Tamoxifen.In vitro functional assessment of 22 newly identified CYP2D6 allelic variants in the Chinese population.Comparison of the Guidelines of the Clinical Pharmacogenetics Implementation Consortium and the Dutch Pharmacogenetics Working Group.Constellation: a tool for rapid, automated phenotype assignment of a highly polymorphic pharmacogene, CYP2D6, from whole-genome sequences.Genetic variability of CYP2D6, CYP2B6, CYP2C9 and CYP2C19 genes across the Italian Peninsula.Have we successfully implemented CYP2D6 genotyping in psychiatry?Impact of CYP2D6 on venlafaxine metabolism in Trinidadian patients with major depressive disorder.Complications of Psychotropic and Pain Medications in an Ultrarapid Metabolizer Patient at the Upper 1% of Cytochrome P450 (CYP450) Function Quantified by Combinatorial CYP450 Genotyping.The challenges of implementing pharmacogenomic testing in the clinic.Impact of CYP2D6 Functional Allelic Variations on Phenoconversion and Drug-Drug Interactions.Safety of single low-dose primaquine in glucose-6-phosphate dehydrogenase deficient falciparum-infected African males: Two open-label, randomized, safety trials.Benefit of pre-emptive pharmacogenetic information on clinical outcome.Ten Years' Experience with the CYP2D6 Activity Score: A Perspective on Future Investigations to Improve Clinical Predictions for Precision Therapeutics.Effect of CYP2D6 variants on venlafaxine metabolism in vitro.Frequency of CYP2D6 Alleles Including Structural Variants in the United States.Enantioselective pharmacokinetics of tramadol and its three main metabolites; impact of CYP2D6, CYP2B6, and CYP3A4 genotype.
P2860
Q28545128-1A1F87CD-1977-49C9-B8C7-D53D5755CB0BQ29247996-DBA9A331-F0CD-4028-B228-A468417B3E27Q30711413-F1E83A7C-C023-4BEC-A625-BCE3E43688B1Q34458720-7E433C4E-3BA5-4B75-BDB1-72DD2488D36EQ35023701-886908CF-A208-49DD-803A-B9383438E304Q35193678-88A5B0EC-3D0F-46BF-8A84-F8846703353AQ35617663-6604A939-F6E0-4D32-8FE9-5231D1651A8DQ35800807-5C8DE501-DD85-43A9-8252-C8FAE27A7976Q36240653-B43B4D3D-BB9E-4CA5-B044-04C5987FFBAAQ36243663-4B6B1C24-C5C6-4E8C-90ED-052E115E2536Q36580824-0BEBE300-5848-44DD-8875-F42D60B8682EQ37047429-BBE9EF38-38B1-4DDE-B520-461676010F5FQ37072158-C6CE3E1C-20CB-4109-BF6E-1F1DB844D834Q37625633-8F2923EB-B167-4AFA-8B3F-39D95F2949EFQ38260323-AF21B14D-5476-488D-9884-44A7B6EC06F5Q38441114-7C0E3FCC-2D0C-4E4C-ACE3-7549B1EE0FB0Q38575185-C4F2A46F-DCAB-4308-A3A6-2F80BCC0E5CCQ39043568-0E13BFFC-71D6-4110-B6AA-2863CA760E8DQ39282325-8076D70F-971F-4628-8603-AAD4C5999E6CQ39869704-C7E3E416-DDDB-434C-806D-E3E3E2F2670EQ40072776-9E8501BD-59CE-4A83-9894-30DCB300292BQ40604148-6C34B27B-C445-4B97-B986-2AF1C8A5CAC4Q40956598-40AA64FF-1646-4EFC-A90C-48C4CFF73F63Q41529888-A40B9DA1-0CA6-4B70-8070-42E78731856FQ41684510-226A9145-96D0-451B-9B18-E276FA61791FQ41732730-D1F854B1-2730-407D-85F0-A1498B9E1103Q46776696-5E886784-315F-4796-940A-5160A1A4D939Q47099388-341C81B0-599D-4DAA-B0C1-79097317849BQ47190575-39971A0C-B430-43AE-BA57-94CA13345A67Q47571812-B5D2FB23-42FC-46AB-95A4-2428EC80C024Q47657184-E7E4196B-7219-452C-AC54-21A5ED45D091Q47885602-791B416C-C0A0-4A6D-8336-6E9224B30DDCQ47929031-9699EA8A-B48D-40A9-96B0-7CE618E0E8E4Q47937029-E38D8B50-E4C8-4865-941B-D8951138FC65Q48021707-74DD371F-D653-4C83-9FB2-C0487A16EA0FQ49612005-96976DA2-F24A-4E79-86F5-F9AADCF7A629Q52315457-5BACD774-B309-4195-9C78-5B11DB73CF19Q52821146-1A974FDF-BC0E-417E-8813-F96975C12EE9Q55087082-395A36D7-AA2C-4F84-B534-6DB30FBF69EBQ55506508-4EB630FC-8EA7-4DEC-AE18-094314379A44
P2860
Challenges in CYP2D6 phenotype assignment from genotype data: a critical assessment and call for standardization.
description
2014 nî lūn-bûn
@nan
2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Challenges in CYP2D6 phenotype ...... and call for standardization.
@ast
Challenges in CYP2D6 phenotype ...... and call for standardization.
@en
type
label
Challenges in CYP2D6 phenotype ...... and call for standardization.
@ast
Challenges in CYP2D6 phenotype ...... and call for standardization.
@en
prefLabel
Challenges in CYP2D6 phenotype ...... and call for standardization.
@ast
Challenges in CYP2D6 phenotype ...... and call for standardization.
@en
P1476
Challenges in CYP2D6 phenotype ...... and call for standardization.
@en
P2093
Andrea Gaedigk
J Kevin Hicks
P304
P356
10.2174/1389200215666140202215316
P407
P50
P577
2014-02-01T00:00:00Z