Pigment epithelium-derived factor blocks tumor extravasation by suppressing amoeboid morphology and mesenchymal proteolysis.
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Rho, ROCK and actomyosin contractility in metastasis as drug targetsPEDF and its roles in physiological and pathological conditions: implication in diabetic and hypoxia-induced angiogenic diseasesAnti-tumor effects of pigment epithelium-derived factor (PEDF): implication for cancer therapy. A mini-reviewLoss of ERα induces amoeboid-like migration of breast cancer cells by downregulating vinculin.Diverse matrix metalloproteinase functions regulate cancer amoeboid migrationHypoxia negatively regulates antimetastatic PEDF in melanoma cells by a hypoxia inducible factor-independent, autophagy dependent mechanism.Regulatory and functional connection of microphthalmia-associated transcription factor and anti-metastatic pigment epithelium derived factor in melanomaARHGAP22 localizes at endosomes and regulates actin cytoskeletonThe interconnectedness of cancer cell signaling.Cell and molecular biology underpinning the effects of PEDF on cancers in general and osteosarcoma in particular.Thrombospondin-1 and pigment epithelium-derived factor enhance responsiveness of KM12 colon tumor to metronomic cyclophosphamide but have disparate effects on tumor metastasis.LKB1 kinase-dependent and -independent defects disrupt polarity and adhesion signaling to drive collagen remodeling during invasion.CD147 regulates cancer migration via direct interaction with Annexin A2 and DOCK3-β-catenin-WAVE2 signalingMelanoma Cells Block PEDF Production in Fibroblasts to Induce the Tumor-Promoting Phenotype of Cancer-Associated FibroblastsThe effects of PEDF on cancer biology: mechanisms of action and therapeutic potentialPigment epithelium-derived factor (PEDF) prevents retinal cell death via PEDF Receptor (PEDF-R): identification of a functional ligand binding siteCancer subclonal genetic architecture as a key to personalized medicine.Searching for Alternatively Spliced Variants of Phospholipase Domain-Containing 2 (Pnpla2), a Novel Gene in the Retina.Proteome screening of pleural effusions identifies galectin 1 as a diagnostic biomarker and highlights several prognostic biomarkers for malignant mesotheliomaEmerging molecular targets in melanoma invasion and metastasis.The many facets of PEDF in drug discovery and disease: a diamond in the rough or split personality disorder?Pigment epithelium-derived factor as a natural matrix metalloproteinase inhibitor: a comparison with classical matrix metalloproteinase inhibitors used for cancer treatment.Pigment epithelium-derived factor upregulates collagen I and downregulates matrix metalloproteinase 2 in osteosarcoma cells, and colocalises to collagen I and heat shock protein 47 in fetal and adult bone.Effects of pigment epithelium derived factor (PEDF) on malignant peripheral nerve sheath tumours (MPNSTs).Overcoming intratumor heterogeneity of polygenic cancer drug resistance with improved biomarker integrationPre-metastatic cancer exosomes induce immune surveillance by patrolling monocytes at the metastatic niche.The Role of Melanoma Cell-Stroma Interaction in Cell Motility, Invasion, and Metastasis
P2860
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P2860
Pigment epithelium-derived factor blocks tumor extravasation by suppressing amoeboid morphology and mesenchymal proteolysis.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Pigment epithelium-derived fac ...... y and mesenchymal proteolysis.
@ast
Pigment epithelium-derived fac ...... y and mesenchymal proteolysis.
@en
type
label
Pigment epithelium-derived fac ...... y and mesenchymal proteolysis.
@ast
Pigment epithelium-derived fac ...... y and mesenchymal proteolysis.
@en
prefLabel
Pigment epithelium-derived fac ...... y and mesenchymal proteolysis.
@ast
Pigment epithelium-derived fac ...... y and mesenchymal proteolysis.
@en
P2093
P2860
P356
P1433
P1476
Pigment epithelium-derived fac ...... gy and mesenchymal proteolysis
@en
P2093
Benilde Jimenez
Cristina Sánchez-Martinez
Omar Ladhani
P2860
P304
P356
10.1593/NEO.11446
P577
2011-07-01T00:00:00Z