RPEL proteins are the molecular targets for CCG-1423, an inhibitor of Rho signaling. - Wikidata - awgldk - TriplyDB

RPEL proteins are the molecular targets for CCG-1423, an inhibitor of Rho signaling.

RPEL proteins are the molecular targets for CCG-1423, an inhibitor of Rho signaling.

http://www.wikidata.org/entity/Q35099772

about

Approaches of targeting Rho GTPases in cancer drug discovery Lentivirus Live Cell Array for Quantitative Assessment of Gene and Pathway Activation during Myogenic Differentiation of Mesenchymal Stem Cells Dynamic tensile forces drive collective cell migration through three-dimensional extracellular matrices.Framework to function: mechanosensitive regulators of gene transcription Local delivery of novel MRTF/SRF inhibitors prevents scar tissue formation in a preclinical model of fibrosis.Cellular mechanisms of tissue fibrosis. 8. Current and future drug targets in fibrosis: focus on Rho GTPase-regulated gene transcription.Emerging roles of the myocardin family of proteins in lipid and glucose metabolism.Myofibroblasts exhibit enhanced fibronectin assembly that is intrinsic to their contractile phenotype.Inhibition of myocardin-related transcription factor/serum response factor signaling decreases lung fibrosis and promotes mesenchymal cell apoptosis.A Role of Myocardin Related Transcription Factor-A (MRTF-A) in Scleroderma Related Fibrosis Stereospecific Inhibitory Effects of CCG-1423 on the Cellular Events Mediated by Myocardin-Related Transcription Factor A.Transcriptional control of cardiac fibroblast plasticity.Cell-cell contact and matrix adhesion promote αSMA expression during TGFβ1-induced epithelial-myofibroblast transition via Notch and MRTF-A RhoA/ROCK signaling regulates TGFβ-induced epithelial-mesenchymal transition of lens epithelial cells through MRTF-A ROCK/actin/MRTF signaling promotes the fibrogenic phenotype of fibroblast-like synoviocytes derived from the temporomandibular joint.Biomechanics of TGFβ-induced epithelial-mesenchymal transition: implications for fibrosis and cancer The myocardin-related transcription factor MKL co-regulates the cellular levels of two profilin isoforms.Pharmacological Inhibition of Myocardin-related Transcription Factor Pathway Blocks Lung Metastases of RhoC-Overexpressing Melanoma.Photo-cross-linked small-molecule affinity matrix as a tool for target identification of bioactive small molecules.The role of small GTPases of the Rho/Rac family in TGF-β-induced EMT and cell motility in cancer.A novel inhibitory mechanism of MRTF-A/B on the ICAM-1 gene expression in vascular endothelial cells.Regulated methionine oxidation by monooxygenases.Pharmacological intervention of MKL/SRF signaling by CCG-1423 impedes endothelial cell migration and angiogenesis.Matrix Rigidity Mediates TGFβ1-Induced Epithelial-Myofibroblast Transition by Controlling Cytoskeletal Organization and MRTF-A Localization.

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RPEL proteins are the molecular targets for CCG-1423, an inhibitor of Rho signaling.

http://www.wikidata.org/entity/Q35099772

description

2014 nî lūn-bûn

@nan

2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի փետրվարին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

@zh-mo

2014年論文

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2014年论文

@wuu

name

RPEL proteins are the molecular targets for CCG-1423, an inhibitor of Rho signaling.

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RPEL proteins are the molecular targets for CCG-1423, an inhibitor of Rho signaling.

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type

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RPEL proteins are the molecular targets for CCG-1423, an inhibitor of Rho signaling.

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RPEL proteins are the molecular targets for CCG-1423, an inhibitor of Rho signaling.

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prefLabel

RPEL proteins are the molecular targets for CCG-1423, an inhibitor of Rho signaling.

@ast

RPEL proteins are the molecular targets for CCG-1423, an inhibitor of Rho signaling.

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RPEL proteins are the molecular targets for CCG-1423, an inhibitor of Rho signaling.

@en

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Bunta Watanabe

http://www.w3.org/2001/XMLSchema#string

Ken'ichiro Hayashi

http://www.w3.org/2001/XMLSchema#string

Saki Minami

http://www.w3.org/2001/XMLSchema#string

Tsuyoshi Morita

http://www.w3.org/2001/XMLSchema#string

Yoshiaki Nakagawa

http://www.w3.org/2001/XMLSchema#string

P2860

G-actin regulates the shuttling and PP1 binding of the RPEL protein Phactr1 to control actomyosin assembly

An actin-regulated importin α/β-dependent extended bipartite NLS directs nuclear import of MRTF-A

Megakaryoblastic leukemia factor-1 transduces cytoskeletal signals and induces smooth muscle cell differentiation from undifferentiated embryonic stem cells

Potentiation of serum response factor activity by a family of myocardin-related transcription factors.

Involvement of a human gene related to the Drosophila spen gene in the recurrent t(1;22) translocation of acute megakaryocytic leukemia

Dual roles of myocardin-related transcription factors in epithelial mesenchymal transition via slug induction and actin remodeling

Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor

Bone morphogenetic protein-induced MSX1 and MSX2 inhibit myocardin-dependent smooth muscle gene transcription

The serum response factor coactivator myocardin is required for vascular smooth muscle development

Requirement of myocardin-related transcription factor-B for remodeling of branchial arch arteries and smooth muscle differentiation

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3928398

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