Sit down, relax and unwind: structural insights into RecQ helicase mechanisms.
about
Structural and functional analyses of disease-causing missense mutations in Bloom syndrome proteinCrystal structure of the HRDC domain of human Werner syndrome protein, WRNAtomic structures and functional implications of the archaeal RecQ-like helicase HjmA Decade of Biochemical and Structural Studies of the DNA Repair Machinery of Deinococcus radiodurans: Major Findings, Functional and Mechanistic Insight and ChallengesMobility in the structure of E.coli recQ helicase upon substrate binding as seen from molecular dynamics simulations.In silico reversal of repeat-induced point mutation (RIP) identifies the origins of repeat families and uncovers obscured duplicated genes.Does BLM helicase unwind nucleosomal DNA?A helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation.Putative DNA G-quadruplex formation within the promoters of Plasmodium falciparum var genes.Characterization of biochemical properties of Bacillus subtilis RecQ helicaseThe HRDC domain of E. coli RecQ helicase controls single-stranded DNA translocation and double-stranded DNA unwinding rates without affecting mechanoenzymatic coupling.Developing master keys to brain pathology, cancer and aging from the structural biology of proteins controlling reactive oxygen species and DNA repair.RECQL5 has unique strand annealing properties relative to the other human RecQ helicase proteins.DNA repair and replication fork helicases are differentially affected by alkyl phosphotriester lesion.The Q motif of Fanconi anemia group J protein (FANCJ) DNA helicase regulates its dimerization, DNA binding, and DNA repair function.The arginine finger of the Bloom syndrome protein: its structural organization and its role in energy coupling.Longevity mutation in SCH9 prevents recombination errors and premature genomic instability in a Werner/Bloom model system.Non-Bloom syndrome-associated partial and total loss-of-function variants of BLM helicase.From old organisms to new molecules: integrative biology and therapeutic targets in accelerated human ageing.The role of DNA damage repair in aging of adult stem cellsThe BLM dissolvasome in DNA replication and repair.Genome dynamics in major bacterial pathogens.Probing Genome Maintenance Functions of human RECQ1.Structural mechanisms of human RecQ helicases WRN and BLM.Osteosarcoma: Molecular Pathogenesis and iPSC Modeling.A novel frameshift mutation in BLM gene associated with high sister chromatid exchanges (SCE) in heterozygous family members.Multiple Escherichia coli RecQ helicase monomers cooperate to unwind long DNA substrates: a fluorescence cross-correlation spectroscopy study.WRN helicase unwinds Okazaki fragment-like hybrids in a reaction stimulated by the human DHX9 helicaseNMR structure of the N-terminal-most HRDC1 domain of RecQ helicase from Deinococcus radiodurans.RecQ helicase triggers a binding mode change in the SSB-DNA complex to efficiently initiate DNA unwinding.Single molecule kinetics uncover roles for E. coli RecQ DNA helicase domains and interaction with SSB
P2860
Q24294274-3464474D-835B-426F-A9C6-26D449D32F92Q27643217-4766435E-871B-47AD-9FBE-CA228D71B86BQ27653490-6C3D4233-F4B5-4EAE-969E-FC8B29252A28Q28072374-B3758B83-032E-4643-AFE7-9026FC0DC3A2Q30413261-77ECC239-935B-473C-9106-D992D6032A13Q30497849-3BBA163A-035F-483D-8CD4-ED54E7347565Q30911826-135909B2-EA12-4E1D-B260-AE74E4D40979Q31814841-382EFF71-144D-4CDA-95AE-0F8CFA502795Q33491273-9E7764E9-B574-4D45-87DE-A01D1C35ED32Q34593441-EB33064D-2078-42CD-AB5B-CC461D41CAE1Q35726266-A033BE1F-8F22-4501-A3CF-BCBD8B2F4E5AQ35865533-C53F7E12-E552-430B-9180-FA81701665A5Q35881750-076F14E2-1891-4E25-9DC6-9EFBB1FC2245Q36003726-EE30CB5B-B17E-48FD-A802-91CD2897823CQ36052367-0018B360-581F-41D6-BFD7-5455E8A4B617Q36168680-B3A7DE78-3BAC-42BB-A4F9-7EB647FCC472Q36404930-81E78ADC-61A3-46D7-A410-A7377ED74F5CQ36436735-6818D7F1-19C0-4725-8662-784613BEB2C0Q36895328-D64AC184-C2B2-4FF3-B3B6-C4F8B2E88705Q37045395-B5A9BA14-5FD0-4F04-A397-181A013ED559Q37064133-A5F5C135-6492-4052-907E-17F48C607E73Q37461159-F645117E-13D2-4084-B0BD-D3300215802CQ38201043-C3D72AC9-2E91-4F6D-B202-E1FAEBC62E77Q38268643-79B0BD15-62F8-4E1B-93A1-0890DE429847Q38653083-C3F88B20-65C9-4300-9998-9EE7ADF6A5F5Q38902543-57147D6E-A548-481E-B875-91C4A54DA037Q39761738-749D6680-1D6B-4ACA-9D55-A213A2708AF7Q42004182-B93B719F-56A5-4C24-90F2-A8E0B9BEE9F3Q44438600-7FB05A05-94B1-411A-B5CD-9878FEAB12CAQ47155576-6D0B820F-E488-4FEE-BFB0-27DB34F70643Q57752932-0887118D-BEA9-4931-96D1-5AC8C82FCB29
P2860
Sit down, relax and unwind: structural insights into RecQ helicase mechanisms.
description
2006 nî lūn-bûn
@nan
2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Sit down, relax and unwind: structural insights into RecQ helicase mechanisms.
@ast
Sit down, relax and unwind: structural insights into RecQ helicase mechanisms.
@en
type
label
Sit down, relax and unwind: structural insights into RecQ helicase mechanisms.
@ast
Sit down, relax and unwind: structural insights into RecQ helicase mechanisms.
@en
prefLabel
Sit down, relax and unwind: structural insights into RecQ helicase mechanisms.
@ast
Sit down, relax and unwind: structural insights into RecQ helicase mechanisms.
@en
P2860
P356
P1476
Sit down, relax and unwind: structural insights into RecQ helicase mechanisms.
@en
P2093
Michael P Killoran
P2860
P304
P356
10.1093/NAR/GKL538
P407
P577
2006-08-25T00:00:00Z