Epigenetic determination of a cell-specific gene expression program by ATF-2 and the histone variant macroH2A.
about
Distinct distribution of ectopically expressed histone variants H2A.Bbd and MacroH2A in open and closed chromatin domainsThe histone variant macroH2A1 marks repressed autosomal chromatin, but protects a subset of its target genes from silencingMacro histone H2A1.2 (macroH2A1) protein suppresses mitotic kinase VRK1 during interphaseThe histone variant macroH2A is an epigenetic regulator of key developmental genesS-glutathionylation of IRF3 regulates IRF3-CBP interaction and activation of the IFN beta pathwayWeak but uniform enrichment of the histone variant macroH2A1 along the inactive X chromosomeHistone variants as emerging regulators of embryonic stem cell identityDynamic aberrant NF-κB spurs tumorigenesis: a new model encompassing the microenvironmentThe nsP3 macro domain is important for Sindbis virus replication in neurons and neurovirulence in miceTumor cell survival pathways activated by photodynamic therapy: a molecular basis for pharmacological inhibition strategiesSocial isolation stress induces ATF-7 phosphorylation and impairs silencing of the 5-HT 5B receptor gene.Histone variants: dynamic punctuation in transcription.The histone variant H2A.Bbd is enriched at sites of DNA synthesis.The histone variant MacroH2A1 regulates target gene expression in part by recruiting the transcriptional coregulator PELP1.TLR cross-talk specifically regulates cytokine production by B cells from chronic inflammatory disease patientsHistone variant macroH2A1 deletion in mice causes female-specific steatosis.The histone H2A variant macroH2A1 does not localize to the centrosome.Emerging roles of ATF2 and the dynamic AP1 network in cancer.X chromosome inactivation and differentiation occur readily in ES cells doubly-deficient for macroH2A1 and macroH2A2.Genome-wide distribution of macroH2A1 histone variants in mouse liver chromatin.Mice without macroH2A histone variants.Synergism between DNA methylation and macroH2A1 occupancy in epigenetic silencing of the tumor suppressor gene p16(CDKN2A).Binding of NF-κB to nucleosomes: effect of translational positioning, nucleosome remodeling and linker histone H1.Genomic analysis reveals a novel nuclear factor-κB (NF-κB)-binding site in Alu-repetitive elements.Regulation of u-PAR gene expression by H2A.Z is modulated by the MEK-ERK/AP-1 pathway.Developmental changes in histone macroH2A1-mediated gene regulationMacroH2A1 regulates the balance between self-renewal and differentiation commitment in embryonic and adult stem cells.Helicobacter pylori VacA enhances prostaglandin E2 production through induction of cyclooxygenase 2 expression via a p38 mitogen-activated protein kinase/activating transcription factor 2 cascade in AZ-521 cells.MacroH2A allows ATP-dependent chromatin remodeling by SWI/SNF and ACF complexes but specifically reduces recruitment of SWI/SNF.ATF2 - at the crossroad of nuclear and cytosolic functions.Inheritance and memory of stress-induced epigenome change: roles played by the ATF-2 family of transcription factorsHistone H2A variants in nucleosomes and chromatin: more or less stable?macroH2A1-dependent silencing of endogenous murine leukemia virusesControl of NF-kappaB-dependent transcriptional responses by chromatin organization.Jun dimerization protein 2 controls senescence and differentiation via regulating histone modification.Macro domains as metabolite sensors on chromatin.Histone variants and melanoma: facts and hypotheses.Phosphorylation of activating transcription factor-2 (ATF-2) within the activation domain is a key determinant of sensitivity to tamoxifen in breast cancer.Genetic ablation of macrohistone H2A1 leads to increased leanness, glucose tolerance and energy expenditure in mice fed a high-fat diet.Hyperactivated NF-{kappa}B and AP-1 transcription factors promote highly accessible chromatin and constitutive transcription across the interleukin-6 gene promoter in metastatic breast cancer cells
P2860
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P2860
Epigenetic determination of a cell-specific gene expression program by ATF-2 and the histone variant macroH2A.
description
2006 nî lūn-bûn
@nan
2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Epigenetic determination of a ...... the histone variant macroH2A.
@ast
Epigenetic determination of a ...... the histone variant macroH2A.
@en
type
label
Epigenetic determination of a ...... the histone variant macroH2A.
@ast
Epigenetic determination of a ...... the histone variant macroH2A.
@en
prefLabel
Epigenetic determination of a ...... the histone variant macroH2A.
@ast
Epigenetic determination of a ...... the histone variant macroH2A.
@en
P2860
P356
P1433
P1476
Epigenetic determination of a ...... the histone variant macroH2A.
@en
P2093
Dimitris Thanos
Marios Agelopoulos
P2860
P304
P356
10.1038/SJ.EMBOJ.7601364
P407
P577
2006-10-12T00:00:00Z