Pathway thermodynamics highlights kinetic obstacles in central metabolism.
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Simulating metabolism with statistical thermodynamicsMetabolic energy-based modelling explains product yielding in anaerobic mixed culture fermentationsA genome-scale Escherichia coli kinetic metabolic model k-ecoli457 satisfying flux data for multiple mutant strainsDesign Principles as a Guide for Constraint Based and Dynamic Modeling: Towards an Integrative Workflow.Synthetic and systems biology for microbial production of commodity chemicals.Quantitative determinants of aerobic glycolysis identify flux through the enzyme GAPDH as a limiting step.Concepts, challenges, and successes in modeling thermodynamics of metabolismOrganization of enzyme concentration across the metabolic network in cancer cellsComputational protein design enables a novel one-carbon assimilation pathway.Estimating relative changes of metabolic fluxes.An in vivo metabolic approach for deciphering the product specificity of glycerate kinase proves that both E. coli's glycerate kinases generate 2-phosphoglycerate.Resource constrained flux balance analysis predicts selective pressure on the global structure of metabolic networks.Integrated In Silico Analysis of Pathway Designs for Synthetic Photo-Electro-Autotrophy.Constrained Allocation Flux Balance AnalysisAlcohol Selectivity in a Synthetic Thermophilic n-Butanol Pathway Is Driven by Biocatalytic and Thermostability Characteristics of Constituent EnzymesThe Protein Cost of Metabolic Fluxes: Prediction from Enzymatic Rate Laws and Cost MinimizationHow important is thermodynamics for identifying elementary flux modes?Global characterization of in vivo enzyme catalytic rates and their correspondence to in vitro kcat measurementsExamining Escherichia coli glycolytic pathways, catabolite repression, and metabolite channeling using Δpfk mutants.Mechanistic Analysis of an Engineered Enzyme that Catalyzes the Formose Reaction.Energy Conservation Associated with Ethanol Formation from H2 and CO2 in Clostridium autoethanogenum Involving Electron Bifurcation.Reaction kinetic analysis of the 3-hydroxypropionate/4-hydroxybutyrate CO2 fixation cycle in extremely thermoacidophilic archaea.A Predictive Model for Selective Targeting of the Warburg Effect through GAPDH Inhibition with a Natural Product.Genome-scale modeling and transcriptome analysis of Leuconostoc mesenteroides unravel the redox governed metabolic states in obligate heterofermentative lactic acid bacteria.Holistic bioengineering: rewiring central metabolism for enhanced bioproduction.How can biological modeling help cell biology?Metabolic enzyme cost explains variable trade-offs between microbial growth rate and yield.Bio-transformation of Glycerol to 3-Hydroxypropionic Acid Using Resting Cells of Lactobacillus reuteri.A review of computational tools for design and reconstruction of metabolic pathways.A machine learning approach to predict metabolic pathway dynamics from time-series multiomics data.OptMDFpathway: Identification of metabolic pathways with maximal thermodynamic driving force and its application for analyzing the endogenous CO2 fixation potential of Escherichia coli
P2860
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P2860
Pathway thermodynamics highlights kinetic obstacles in central metabolism.
description
2014 nî lūn-bûn
@nan
2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Pathway thermodynamics highlights kinetic obstacles in central metabolism.
@ast
Pathway thermodynamics highlights kinetic obstacles in central metabolism.
@en
type
label
Pathway thermodynamics highlights kinetic obstacles in central metabolism.
@ast
Pathway thermodynamics highlights kinetic obstacles in central metabolism.
@en
prefLabel
Pathway thermodynamics highlights kinetic obstacles in central metabolism.
@ast
Pathway thermodynamics highlights kinetic obstacles in central metabolism.
@en
P2860
P50
P1476
Pathway thermodynamics highlights kinetic obstacles in central metabolism.
@en
P2860
P304
P356
10.1371/JOURNAL.PCBI.1003483
P577
2014-02-20T00:00:00Z