Pharmacological inhibition of poly(ADP-ribose) polymerase-1 modulates resistance of human glioblastoma stem cells to temozolomide. - Wikidata - awgldk - TriplyDB

Pharmacological inhibition of poly(ADP-ribose) polymerase-1 modulates resistance of human glioblastoma stem cells to temozolomide.

Pharmacological inhibition of poly(ADP-ribose) polymerase-1 modulates resistance of human glioblastoma stem cells to temozolomide.

http://www.wikidata.org/entity/Q35110170

about

Use of poly ADP-ribose polymerase [PARP] inhibitors in cancer cells bearing DDR defects: the rationale for their inclusion in the clinic Stellettin B induces apoptosis in human chronic myeloid leukemia cells via targeting PI3K and Stat5 Antiproliferative effect of ZSTK474 alone or in combination with chemotherapeutic drugs on HL60 and HL60/ADR cells RNA-seq identifies determinants of oxaliplatin sensitivity in colorectal cancer cell lines.PARP targeting counteracts gliomagenesis through induction of mitotic catastrophe and aggravation of deficiency in homologous recombination in PTEN-mutant glioma VB-111: a novel anti-vascular therapeutic for glioblastoma multiforme Retinoblastoma Binding Protein 4 Modulates Temozolomide Sensitivity in Glioblastoma by Regulating DNA Repair Proteins.Temozolomide promotes genomic and phenotypic changes in glioblastoma cells.In Vitro Antileukemia Activity of ZSTK474 on K562 and Multidrug Resistant K562/A02 Cells.Veliparib in combination with radiotherapy for the treatment of MGMT unmethylated glioblastoma.PARP1 expression and its correlation with survival is tumour molecular subtype dependent in glioblastoma.Honokiol Inhibits DNA Polymerases β and λ and Increases Bleomycin Sensitivity of Human Cancer Cells.Differential Potential of Pharmacological PARP Inhibitors for Inhibiting Cell Proliferation and Inducing Apoptosis in Human Breast Cancer Cells.PARP Inhibitor Activity Correlates with SLFN11 Expression and Demonstrates Synergy with Temozolomide in Small Cell Lung Cancer.The anti-vascular endothelial growth factor receptor-1 monoclonal antibody D16F7 inhibits invasiveness of human glioblastoma and glioblastoma stem cells Poly-(ADP-ribose)-polymerase inhibitors as radiosensitizers: a systematic review of pre-clinical and clinical human studies.ABT-888 enhances cytotoxic effects of temozolomide independent of MGMT status in serum free cultured glioma cells.JNK Activation Contributes to Oxidative Stress-Induced Parthanatos in Glioma Cells via Increase of Intracellular ROS Production.ABT-888 restores sensitivity in temozolomide resistant glioma cells and xenografts

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P2860

Pharmacological inhibition of poly(ADP-ribose) polymerase-1 modulates resistance of human glioblastoma stem cells to temozolomide.

http://www.wikidata.org/entity/Q35110170

description

2014 nî lūn-bûn

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2014 թվականի մարտին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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Alessia Muzi

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Daniele Runci

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Federica Pelacchi

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Paola Caiafa

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Roberta Calabrese

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P2860

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

MGMT gene silencing and benefit from temozolomide in glioblastoma.

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

Identification of a cancer stem cell in human brain tumors

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma

Essential role for nuclear PTEN in maintaining chromosomal integrity

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

Drug combination studies and their synergy quantification using the Chou-Talalay method

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Lucia Ricci Vitiani

Grazia Graziani

Roberto Pallini

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