Zscan4 is regulated by PI3-kinase and DNA-damaging agents and directly interacts with the transcriptional repressors LSD1 and CtBP2 in mouse embryonic stem cells
about
Expression analysis of the endogenous Zscan4 locus and its coding proteins in mouse ES cells and preimplantation embryosTransient bursts of Zscan4 expression are accompanied by the rapid derepression of heterochromatin in mouse embryonic stem cellsZscan4 is expressed specifically during late meiotic prophase in both spermatogenesis and oogenesis.Zscan4 Is Activated after Telomere Shortening in Mouse Embryonic Stem Cells.MERVL/Zscan4 Network Activation Results in Transient Genome-wide DNA Demethylation of mESCs.ZSCAN4 is negatively regulated by the ubiquitin-proteasome system and the E3 ubiquitin ligase RNF20.Feeders facilitate telomere maintenance and chromosomal stability of embryonic stem cells.
P2860
Q34541919-9987CAC1-C3BC-45CF-9B63-49876AA48C74Q36131205-D155CEBA-F6E5-4F9D-B446-D71CFBB5D7D2Q37643978-C9B8CDC0-42AF-4D6F-96F3-A562EAE02353Q40255720-77EE0E43-8C62-4F06-9CA7-6450B1C093E8Q41371125-E0206E16-CFA0-492B-821C-59788DBF4766Q52373382-93177566-ED35-4144-8343-062C094DC06EQ55506011-9ED1CB68-22F0-4FCD-96C6-F07FC8A0AD57
P2860
Zscan4 is regulated by PI3-kinase and DNA-damaging agents and directly interacts with the transcriptional repressors LSD1 and CtBP2 in mouse embryonic stem cells
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Zscan4 is regulated by PI3-kin ...... in mouse embryonic stem cells
@ast
Zscan4 is regulated by PI3-kin ...... in mouse embryonic stem cells
@en
type
label
Zscan4 is regulated by PI3-kin ...... in mouse embryonic stem cells
@ast
Zscan4 is regulated by PI3-kin ...... in mouse embryonic stem cells
@en
prefLabel
Zscan4 is regulated by PI3-kin ...... in mouse embryonic stem cells
@ast
Zscan4 is regulated by PI3-kin ...... in mouse embryonic stem cells
@en
P2093
P2860
P1433
P1476
Zscan4 is regulated by PI3-kin ...... in mouse embryonic stem cells
@en
P2093
Benjamin Kumpfmueller
Heather K Bone
Hitoshi Niwa
Julian B Chaudhuri
Melanie J Welham
Michael Buchholz
Michael P Storm
Yolanda Sanchez Ripoll
P2860
P304
P356
10.1371/JOURNAL.PONE.0089821
P407
P50
P577
2014-03-03T00:00:00Z