A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene. - Wikidata - awgldk - TriplyDB

A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene.

A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene.

http://www.wikidata.org/entity/Q35110976

about

A Chimeric HIV-1 gp120 Fused with Vaccinia Virus 14K (A27) Protein as an HIV Immunogen Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G Protein stability: a crystallographer's perspective Structural Constraints Determine the Glycosylation of HIV-1 Envelope Trimers Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes Thermostability of Well-Ordered HIV Spikes Correlates with the Elicitation of Autologous Tier 2 Neutralizing Antibodies HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure.Antigenicity-defined conformations of an extremely neutralization-resistant HIV-1 envelope spike.Glycine Substitution at Helix-to-Coil Transitions Facilitates the Structural Determination of a Stabilized Subtype C HIV Envelope Glycoprotein HIV-1 Envelope Trimer Design and Immunization Strategies To Induce Broadly Neutralizing Antibodies.Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches.Reducing V3 Antigenicity and Immunogenicity on Soluble, Native-Like HIV-1 Env SOSIP Trimers Strategies to guide the antibody affinity maturation process A New Approach to Produce HIV-1 Envelope Trimers: BOTH CLEAVAGE AND PROPER GLYCOSYLATION ARE ESSENTIAL TO GENERATE AUTHENTIC TRIMERS Murine Antibody Responses to Cleaved Soluble HIV-1 Envelope Trimers Are Highly Restricted in Specificity.Discrete partitioning of HIV-1 Env forms revealed by viral capture.Presenting native-like HIV-1 envelope trimers on ferritin nanoparticles improves their immunogenicity.Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike.Design and structure of two HIV-1 clade C SOSIP.664 trimers that increase the arsenal of native-like Env immunogens.Broadly Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1 Env.Sequential and Simultaneous Immunization of Rabbits with HIV-1 Envelope Glycoprotein SOSIP.664 Trimers from Clades A, B and C.Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice.Diversification in the HIV-1 Envelope Hyper-variable Domains V2, V4, and V5 and Higher Probability of Transmitted/Founder Envelope Glycosylation Favor the Development of Heterologous Neutralization Breadth Antigenic characterization of the human immunodeficiency virus (HIV-1) envelope glycoprotein precursor incorporated into nanodiscs.Engineering and Characterization of a Fluorescent Native-Like HIV-1 Envelope Glycoprotein Trimer.Chemical Cross-Linking Stabilizes Native-Like HIV-1 Envelope Glycoprotein Trimer Antigens Structural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site.Achieving Potent Autologous Neutralizing Antibody Responses against Tier 2 HIV-1 Viruses by Strategic Selection of Envelope Immunogens.Native Conformation and Canonical Disulfide Bond Formation Are Interlinked Properties of HIV-1 Env Glycoproteins.Immunogenicity of a Prefusion HIV-1 Envelope Trimer in Complex with a Quaternary-Structure-Specific Antibody.Range of CD4-Bound Conformations of HIV-1 gp120, as Defined Using Conditional CD4-Induced Antibodies.Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles Uncleaved prefusion-optimized gp140 trimers derived from analysis of HIV-1 envelope metastability.Macrocyclic Envelope Glycoprotein Antagonists that Irreversibly Inactivate HIV-1 before Host Cell Encounter.Significant contribution of subtype G to HIV-1 genetic complexity in Nigeria identified by a newly developed subtyping assay specific for subtype G and CRF02_AG.HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies.Epitope-Independent Purification of Native-Like Envelope Trimers from Diverse HIV-1 Isolates.Cryo-EM structure of a CD4-bound open HIV-1 envelope trimer reveals structural rearrangements of the gp120 V1V2 loop.

P2860

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P2860

A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene.

http://www.wikidata.org/entity/Q35110976

description

2015 nî lūn-bûn

@nan

2015 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2015 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2015年の論文

@ja

2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

name

A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene.

@ast

A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene.

@en

type

label

A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene.

@ast

A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene.

@en

prefLabel

A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene.

@ast

A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene.

@en

P1433

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P1476

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P2093

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P2860

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P50

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P932

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P1433

Journal of Virology

P1476

A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene.

@en

P2093

Albert Cupo

http://www.w3.org/2001/XMLSchema#string

Andrew B Ward

http://www.w3.org/2001/XMLSchema#string

Anila Yasmeen

http://www.w3.org/2001/XMLSchema#string

Dennis R Burton

http://www.w3.org/2001/XMLSchema#string

Gabriel Ozorowski

http://www.w3.org/2001/XMLSchema#string

Helen J Kim

http://www.w3.org/2001/XMLSchema#string

Jacob Korzun

http://www.w3.org/2001/XMLSchema#string

John P Moore

http://www.w3.org/2001/XMLSchema#string

Kevin de Los Reyes

http://www.w3.org/2001/XMLSchema#string

Michael Golabek

http://www.w3.org/2001/XMLSchema#string

P2860

Antibodies in HIV-1 vaccine development and therapy

Molecular architecture of native HIV-1 gp120 trimers

Broadly Neutralizing Antibody PGT121 Allosterically Modulates CD4 Binding via Recognition of the HIV-1 gp120 V3 Base and Multiple Surrounding Glycans

Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer

Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer

Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign

Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike

Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers.

UCSF Chimera--a visualization system for exploratory research and analysis

EMAN: semiautomated software for high-resolution single-particle reconstructions

P304

3380-3395

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1128/JVI.03473-14

http://www.w3.org/2001/XMLSchema#string

P407

P433

6

http://www.w3.org/2001/XMLSchema#string

P478

89

http://www.w3.org/2001/XMLSchema#string

P50

Jean-Philippe Julien

Ian Andrew Wilson

P577

2015-01-14T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

270908923

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P698

25589637

http://www.w3.org/2001/XMLSchema#string

P932

4337520

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