Notch1 inhibition alters the CD44hi/CD24lo population and reduces the formation of brain metastases from breast cancer. - Wikidata - awgldk - TriplyDB

Notch1 inhibition alters the CD44hi/CD24lo population and reduces the formation of brain metastases from breast cancer.

Notch1 inhibition alters the CD44hi/CD24lo population and reduces the formation of brain metastases from breast cancer.

http://www.wikidata.org/entity/Q35119038

about

Metastatic cancer stem cells: from the concept to therapeutics The role of cancer stem cells and miRNAs in defining the complexities of brain metastasis Breast cancer brain metastases: biology and new clinical perspectives A synthetic triterpenoid CDDO-Im inhibits tumorsphere formation by regulating stem cell signaling pathways in triple-negative breast cancer Discovery of biomarkers predictive of GSI response in triple-negative breast cancer and adenoid cystic carcinoma.Epithelial-to-mesenchymal transition and the cancer stem cell phenotype: insights from cancer biology with therapeutic implications for colorectal cancer.HER2 in Breast Cancer Stemness: A Negative Feedback Loop towards Trastuzumab Resistance.Cancer cell redirection biomarker discovery using a mutual information approach HES1-mediated inhibition of Notch1 signaling by a Gemini vitamin D analog leads to decreased CD44(+)/CD24(-/low) tumor-initiating subpopulation in basal-like breast cancer.NOTCH reprograms mitochondrial metabolism for proinflammatory macrophage activation The role of Notch signaling in muscle progenitor cell depletion and the rapid onset of histopathology in muscular dystrophy.Emerging roles of the FBW7 tumour suppressor in stem cell differentiation.A novel Monoclonal Antibody against Notch1 Targets Leukemia-associated Mutant Notch1 and Depletes Therapy Resistant Cancer Stem Cells in Solid Tumors.Breaking and entering into the CNS: clues from solid tumor and nonmalignant models with relevance to hematopoietic malignancies.Understanding Heterogeneity and Permeability of Brain Metastases in Murine Models of HER2-Positive Breast Cancer Through Magnetic Resonance Imaging: Implications for Detection and Therapy.Arsenic trioxide inhibits cell growth and induces apoptosis through inactivation of notch signaling pathway in breast cancer.Nicastrin regulates breast cancer stem cell properties and tumor growth in vitro and in vivo Innovative therapeutic strategies in the treatment of brain metastases.Blockade of Autocrine TGF-β Signaling Inhibits Stem Cell Phenotype, Survival, and Metastasis of Murine Breast Cancer Cells.Reactive astrocytes promote the metastatic growth of breast cancer stem-like cells by activating Notch signalling in brain.Understanding and targeting cancer stem cells: therapeutic implications and challenges.Notch signaling: targeting cancer stem cells and epithelial-to-mesenchymal transition Triple negative breast cancer initiating cell subsets differ in functional and molecular characteristics and in γ-secretase inhibitor drug responses.The identification and characterization of breast cancer CTCs competent for brain metastasis.Effects of tyrosine kinase inhibitors and CXCR4 antagonist on tumor growth and angiogenesis in rat glioma model: MRI and protein analysis study.Interplay between CCR7 and Notch1 axes promotes stemness in MMTV-PyMT mammary cancer cells Lung-derived factors mediate breast cancer cell migration through CD44 receptor-ligand interactions in a novel ex vivo system for analysis of organ-specific soluble proteins.Therapeutic targets in triple negative breast cancer.Stem cells in gastrointestinal cancers: The road less travelled.Regulation of breast cancer stem cell features.Mystery of the brain metastatic disease in breast cancer patients: improved patient stratification, disease prediction and targeted prevention on the horizon?The Implications and Future Perspectives of Nanomedicine for Cancer Stem Cell Targeted Therapies.Cancer stem cell markers: premises and prospects.Unlocking Doors without Keys: Activation of Src by Truncated C-terminal Intracellular Receptor Tyrosine Kinases Lacking Tyrosine Kinase Activity.Breast cancer stem cells: are we ready to go from bench to bedside?Targeting BCRP/ABCG2 by RNA interference enhances the chemotherapy sensitivity of human colon cancer side population cells.Analysis of radiation therapy in a model of triple-negative breast cancer brain metastasis.Breast cancer stem cell: the roles and therapeutic implications.A truncated-Flt1 isoform of breast cancer cells is upregulated by Notch and downregulated by retinoic acid.Inhibition of CK2α down-regulates Notch1 signalling in lung cancer cells.

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P2860

Notch1 inhibition alters the CD44hi/CD24lo population and reduces the formation of brain metastases from breast cancer.

http://www.wikidata.org/entity/Q35119038

description

2011 nî lūn-bûn

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2011 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հունիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Notch1 inhibition alters the C ...... metastases from breast cancer.

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Notch1 inhibition alters the C ...... metastases from breast cancer.

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type

label

Notch1 inhibition alters the C ...... metastases from breast cancer.

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Notch1 inhibition alters the C ...... metastases from breast cancer.

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prefLabel

Notch1 inhibition alters the C ...... metastases from breast cancer.

@ast

Notch1 inhibition alters the C ...... metastases from breast cancer.

@en

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1541-7786.MCR-10-0457

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Molecular Cancer Research

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Notch1 inhibition alters the C ...... metastases from breast cancer

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Alison L Allan

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Carmen Simedrea

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Diane Palmieri

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Patricia S Steeg

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Paula J Foster

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P2860

Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells

The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts

Genes that mediate breast cancer metastasis to the brain

ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome

Prospective identification of tumorigenic breast cancer cells

A new mathematical model for relative quantification in real-time RT-PCR

A gene-expression signature as a predictor of survival in breast cancer

A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE

High-level JAG1 mRNA and protein predict poor outcome in breast cancer

Genes that mediate breast cancer metastasis to lung

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834-844

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scholarly article

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10.1158/1541-7786.MCR-10-0457

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7

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9

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Ann F. Chambers

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Emeline Julie Ribot

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2011-06-10T00:00:00Z

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21665937

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3140630

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