D2 receptor overexpression in the striatum leads to a deficit in inhibitory transmission and dopamine sensitivity in mouse prefrontal cortex. - Wikidata - awgldk - TriplyDB

D2 receptor overexpression in the striatum leads to a deficit in inhibitory transmission and dopamine sensitivity in mouse prefrontal cortex.

D2 receptor overexpression in the striatum leads to a deficit in inhibitory transmission and dopamine sensitivity in mouse prefrontal cortex.

http://www.wikidata.org/entity/Q35123090

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Translational Rodent Paradigms to Investigate Neuromechanisms Underlying Behaviors Relevant to Amotivation and Altered Reward Processing in Schizophrenia Neuronal mechanisms and circuits underlying repetitive behaviors in mouse models of autism spectrum disorder Dopamine receptors - IUPHAR Review 13 The detection of novelty relies on dopaminergic signaling: evidence from apomorphine's impact on the novelty N2 Oxytocin improves behavioral and electrophysiological deficits in a novel Shank3-deficient rat Inhibition of 14-3-3 Proteins Leads to Schizophrenia-Related Behavioral Phenotypes and Synaptic Defects in Mice.Perspectives on the mGluR2/3 agonists as a therapeutic target for schizophrenia: Still promising or a dead end?Deletion of GSK3β in D2R-expressing neurons reveals distinct roles for β-arrestin signaling in antipsychotic and lithium action.Reward processing in autism: a thematic series.Dissociation of hedonic reaction to reward and incentive motivation in an animal model of the negative symptoms of schizophrenia Striatal phosphodiesterase 10A and medial prefrontal cortical thickness in patients with schizophrenia: a PET and MRI study MicroRNA-9 and microRNA-326 regulate human dopamine D2 receptor expression, and the microRNA-mediated expression regulation is altered by a genetic variant Disruption of Akt signaling decreases dopamine sensitivity in modulation of inhibitory synaptic transmission in rat prefrontal cortex.Increased dopamine D2 receptor activity in the striatum alters the firing pattern of dopamine neurons in the ventral tegmental area.Using human brain imaging studies as a guide toward animal models of schizophrenia.Loss of dysbindin-1 in mice impairs reward-based operant learning by increasing impulsive and compulsive behavior Motivational salience and genetic variability of dopamine D2 receptor expression interact in the modulation of interference processing The impact of motivation on cognitive performance in an animal model of the negative and cognitive symptoms of schizophrenia.Losing your inhibition: linking cortical GABAergic interneurons to schizophrenia.Dopamine modulation of learning and memory in the prefrontal cortex: insights from studies in primates, rodents, and birds.Elevated dopamine D2 receptor in prefrontal cortex of CUMS rats is associated with downregulated cAMP-independent signaling pathway.Electrophysiological endophenotypes in rodent models of schizophrenia and psychosis.Dopamine D1 or D2 receptor-expressing neurons in the central nervous system.Preclinical Models to Investigate Mechanisms of Negative Symptoms in Schizophrenia.Insights About Striatal Circuit Function and Schizophrenia From a Mouse Model of Dopamine D2 Receptor Upregulation.A study on the mechanism by which MDMA protects against dopaminergic dysfunction after minimal traumatic brain injury (mTBI) in mice.Selective blockade of dopamine D3 receptors enhances while D2 receptor antagonism impairs social novelty discrimination and novel object recognition in rats: a key role for the prefrontal cortex.MPTP-Induced Dopamine Depletion in Basolateral Amygdala via Decrease of D2R Activation Suppresses GABAA Receptors Expression and LTD Induction Leading to Anxiety-Like Behaviors.Striatal D2 receptors regulate dendritic morphology of medium spiny neurons via Kir2 channels.Hyperdopaminergic modulation of inhibitory transmission is dependent on GSK-3β signaling-mediated trafficking of GABAA receptors.Distinct Synaptic Strengthening of the Striatal Direct and Indirect Pathways Drives Alcohol Consumption.The Effects of Cariprazine and Aripiprazole on PCP-Induced Deficits on Attention Assessed in the 5-Choice Serial Reaction Time Task.Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings

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D2 receptor overexpression in the striatum leads to a deficit in inhibitory transmission and dopamine sensitivity in mouse prefrontal cortex.

http://www.wikidata.org/entity/Q35123090

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2011 nî lūn-bûn

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2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2011 թվականի հուլիսին հրատարակված գիտական հոդված

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2011年の論文

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Proceedings of the National Academy of Sciences of the United States of America

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D2 receptor overexpression in ...... ity in mouse prefrontal cortex

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Christoph Kellendonk

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Eric R Kandel

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Wen-Jun Gao

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Yan-Chun Li

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P2860

The dopamine hypothesis of schizophrenia: version III--the final common pathway

Increased baseline occupancy of D2 receptors by dopamine in schizophrenia

Impaired timing precision produced by striatal D2 receptor overexpression is mediated by cognitive and motivational deficits

Mechanisms Underlying Differential D1 versus D2 Dopamine Receptor Regulation of Inhibition in Prefrontal Cortex

Cortical inhibitory neurons and schizophrenia

Implications of normal brain development for the pathogenesis of schizophrenia

Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence

Do we still believe in the dopamine hypothesis? New data bring new evidence.

Cortico-Basal Ganglia reward network: microcircuitry.

The role of in vivo molecular imaging with PET and SPECT in the elucidation of psychiatric drug action and new drug development.

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108

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Eleanor H Simpson

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51468228

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21730148

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corpus striatum

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3141950

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