Molecular subtypes of osteosarcoma identified by reducing tumor heterogeneity through an interspecies comparative approach
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Man's best friend: what can pet dogs teach us about non-Hodgkin's lymphoma?A quantitative comparison of human HT-1080 fibrosarcoma cells and primary human dermal fibroblasts identifies a 3D migration mechanism with properties unique to the transformed phenotypeEmbracing Integrative Multiomics ApproachesComparative oncology: what dogs and other species can teach us about humans with cancerCanine cancer immunotherapy studies: linking mouse and human.Digital expression profiling identifies RUNX2, CDC5L, MDM2, RECQL4, and CDK4 as potential predictive biomarkers for neo-adjuvant chemotherapy response in paediatric osteosarcoma.Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/BEvaluation of P16 expression in canine appendicular osteosarcoma.Combinatorial treatment of DNA and chromatin-modifying drugs cause cell death in human and canine osteosarcoma cell lines.Arginase treatment prevents the recovery of canine lymphoma and osteosarcoma cells resistant to the toxic effects of prolonged arginine deprivationInterleukin-8 promotes canine hemangiosarcoma growth by regulating the tumor microenvironment.Gene expression profiles resulting from stable loss of p53 mirrors its role in tissue differentiation.Global gene expression analysis of canine cutaneous mast cell tumor: could molecular profiling be useful for subtype classification and prognostication?MiR-9 is overexpressed in spontaneous canine osteosarcoma and promotes a metastatic phenotype including invasion and migration in osteoblasts and osteosarcoma cell lines.Aberrant Retinoblastoma (RB)-E2F Transcriptional Regulation Defines Molecular Phenotypes of Osteosarcoma.Molecular profiling reveals prognostically significant subtypes of canine lymphoma.Exome sequencing of osteosarcoma reveals mutation signatures reminiscent of BRCA deficiencyInflammation, apoptosis, and necrosis induced by neoadjuvant fas ligand gene therapy improves survival of dogs with spontaneous bone cancerMicroRNAs at the human 14q32 locus have prognostic significance in osteosarcoma.A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis.Breed-predispositions to cancer in pedigree dogs.MicroRNA paraffin-based studies in osteosarcoma reveal reproducible independent prognostic profiles at 14q32.Canine osteosarcoma cell lines from patients with differing serum alkaline phosphatase concentrations display no behavioural differences in vitro.Evaluation of optimal water fluoridation on the incidence and skeletal distribution of naturally arising osteosarcoma in pet dogs.Heterotypic mouse models of canine osteosarcoma recapitulate tumor heterogeneity and biological behavior.Identification of three molecular and functional subtypes in canine hemangiosarcoma through gene expression profiling and progenitor cell characterization.Canine osteosarcoma: a naturally occurring disease to inform pediatric oncology.Wnt/β-catenin signaling plays an ever-expanding role in stem cell self-renewal, tumorigenesis and cancer chemoresistance.Application of post-genomic techniques in dog cancer research.Canine osteosarcoma cells exhibit resistance to aurora kinase inhibitors.Imatinib and Dasatinib Inhibit Hemangiosarcoma and Implicate PDGFR-β and Src in Tumor Growth.CD40 ligand is necessary and sufficient to support primary diffuse large B-cell lymphoma cells in culture: a tool for in vitro preclinical studies with primary B-cell malignanciesComparative Aspects of Osteosarcoma Pathogenesis in Humans and Dogs.Comparative oncology evaluation of intravenous recombinant oncolytic Vesicular Stomatitis Virus therapy in spontaneous canine cancer.Comparative transcriptome analysis quantifies immune cell transcript levels, metastatic progression and survival in osteosarcoma.Understanding the Osteosarcoma Pathobiology: A Comparative Oncology Approach.MiR-34a regulates the invasive capacity of canine osteosarcoma cell lines.Modulation of fatty acid metabolism and immune suppression are features of in vitro tumour sphere formation in ontogenetically distinct dog cancers.Osteosarcoma: Accelerating Progress Makes for a Hopeful Future.From humans to hydra: patterns of cancer across the tree of life.
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P2860
Molecular subtypes of osteosarcoma identified by reducing tumor heterogeneity through an interspecies comparative approach
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Molecular subtypes of osteosar ...... erspecies comparative approach
@ast
Molecular subtypes of osteosar ...... erspecies comparative approach
@en
type
label
Molecular subtypes of osteosar ...... erspecies comparative approach
@ast
Molecular subtypes of osteosar ...... erspecies comparative approach
@en
prefLabel
Molecular subtypes of osteosar ...... erspecies comparative approach
@ast
Molecular subtypes of osteosar ...... erspecies comparative approach
@en
P2093
P2860
P4510
P50
P1433
P1476
Molecular subtypes of osteosar ...... erspecies comparative approach
@en
P2093
Aaron L Sarver
David M Getzy
Gary R Cutter
Katherine J Gavin
Milcah C Scott
Robert A Newman
Venugopal Thayanithy
William C Kisseberth
P2860
P304
P356
10.1016/J.BONE.2011.05.008
P577
2011-05-15T00:00:00Z