Loading of the 3F3/2 antigen onto kinetochores is dependent on the ordered assembly of the spindle checkpoint proteins.
about
The crystal structure of the N-terminal region of BUB1 provides insight into the mechanism of BUB1 recruitment to kinetochoresBub1 is essential for assembly of the functional inner centromere.Kinetochore function is controlled by a phospho-dependent coexpansion of inner and outer components.Drosophila Polo regulates the spindle assembly checkpoint through Mps1-dependent BubR1 phosphorylationSpatial regulation of the spindle assembly checkpoint and anaphase-promoting complex in Aspergillus nidulansTension-sensitive Plk1 phosphorylation on BubR1 regulates the stability of kinetochore microtubule interactions.Spindle checkpoint-independent inhibition of mitotic chromosome segregation by Drosophila Mps1.Cdk1 phosphorylation of BubR1 controls spindle checkpoint arrest and Plk1-mediated formation of the 3F3/2 epitope.Bub1 kinase activity drives error correction and mitotic checkpoint control but not tumor suppression.Requirements for protein phosphorylation and the kinase activity of polo-like kinase 1 (Plk1) for the kinetochore function of mitotic arrest deficiency protein 1 (Mad1).Mps1 kinase activity restrains anaphase during an unperturbed mitosis and targets Mad2 to kinetochores.BubR1 and APC/EB1 cooperate to maintain metaphase chromosome alignment.Plo1 phosphorylates Dam1 to promote chromosome bi-orientation in fission yeast.All together now: Polo joins the kinase network controlling the spindle assembly checkpoint in Drosophila.
P2860
Q24658416-C777CFE7-3EFE-4490-BCD0-322D214012CEQ24683337-0C0751D0-4990-4E3B-A46E-32EC6B80B9FAQ27309180-A4101225-4C47-46B0-BFD7-DACCA340CB02Q30540597-3C030F9B-F7DF-4B01-B92B-6DA2854DE461Q35019961-2A43C26D-FA27-4C0B-A18D-B0988B6CFAE5Q35946386-8445E782-3FE1-48F0-8D6D-18CCB7E890A1Q36030477-8D3B7FCE-D293-4EF3-9F6B-173CB2A6D6AEQ36149262-FD811EAC-866E-456F-A4EF-D2C50961D180Q36455895-3B62DE1C-2C87-4C15-8773-3BC1C32EF6CCQ37015055-C3B9DF07-0349-4849-933E-870AEF0A3E58Q39131699-77FF4B2A-1509-4D5E-9BBB-6944CA56D93BQ39746594-F8A1F34E-AEA8-4C08-9B41-884DF94E4CD9Q41809145-4352E659-F63D-432D-92E9-014D7691E09FQ41880466-A15B2FC1-CEA0-4349-88A1-35A89FD974CA
P2860
Loading of the 3F3/2 antigen onto kinetochores is dependent on the ordered assembly of the spindle checkpoint proteins.
description
2006 nî lūn-bûn
@nan
2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Loading of the 3F3/2 antigen o ...... e spindle checkpoint proteins.
@ast
Loading of the 3F3/2 antigen o ...... e spindle checkpoint proteins.
@en
type
label
Loading of the 3F3/2 antigen o ...... e spindle checkpoint proteins.
@ast
Loading of the 3F3/2 antigen o ...... e spindle checkpoint proteins.
@en
prefLabel
Loading of the 3F3/2 antigen o ...... e spindle checkpoint proteins.
@ast
Loading of the 3F3/2 antigen o ...... e spindle checkpoint proteins.
@en
P2860
P356
P1476
Loading of the 3F3/2 antigen o ...... e spindle checkpoint proteins.
@en
P2093
Guowei Fang
Oi Kwan Wong
P2860
P304
P356
10.1091/MBC.E06-04-0346
P577
2006-08-02T00:00:00Z