The polypyrimidine tract binding protein (PTB) represses splicing of exon 6B from the beta-tropomyosin pre-mRNA by directly interfering with the binding of the U2AF65 subunit
about
Next-generation SELEX identifies sequence and structural determinants of splicing factor binding in human pre-mRNA sequenceStructure of the Yeast SR Protein Npl3 and Interaction with mRNA 3′-End Processing SignalsGenome-wide analysis of PTB-RNA interactions reveals a strategy used by the general splicing repressor to modulate exon inclusion or skippingMechanisms of alternative splicing regulation: insights from molecular and genomics approachesNew function for the RNA helicase p68/DDX5 as a modifier of MBNL1 activity on expanded CUG repeatsCrossregulation and functional redundancy between the splicing regulator PTB and its paralogs nPTB and ROD1High expression of PTBP1 promote invasion of colorectal cancer by alternative splicing of cortactin.Allele-specific recognition of the 3' splice site of INS intron 1Computational identification of tissue-specific alternative splicing elements in mouse genes from RNA-SeqA biophysical model for identifying splicing regulatory elements and their interactions.Neuronal regulation of pre-mRNA splicing by polypyrimidine tract binding proteins, PTBP1 and PTBP2.Triplex DNA-binding proteins are associated with clinical outcomes revealed by proteomic measurements in patients with colorectal cancer.Direct competition between hnRNP C and U2AF65 protects the transcriptome from the exonization of Alu elementsTannic acid facilitates expression of the polypyrimidine tract binding protein and alleviates deleterious inclusion of CHRNA1 exon P3A due to an hnRNP H-disrupting mutation in congenital myasthenic syndromePolypyrimidine tract binding protein prevents activity of an intronic regulatory element that promotes usage of a composite 3'-terminal exon.Large-scale remodeling of a repressed exon ribonucleoprotein to an exon definition complex active for splicing.Alternative splicing of U2AF1 reveals a shared repression mechanism for duplicated exons.U1 snRNA directly interacts with polypyrimidine tract-binding protein during splicing repression.Polypyrimidine tract binding protein inhibits IgM pre-mRNA splicing by diverting U2 snRNA base-pairing away from the branch point.New insights into functional roles of the polypyrimidine tract-binding protein.Diverse regulation of 3' splice site usage.HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer.Roles of polypyrimidine tract binding proteins in major immediate-early gene expression and viral replication of human cytomegalovirus.Polypyrimidine tract-binding protein (PTB) differentially affects malignancy in a cell line-dependent mannerPolypyrimidine tract binding protein controls the transition from exon definition to an intron defined spliceosome.The Role of Polypyrimidine Tract-Binding Proteins and Other hnRNP Proteins in Plant Splicing Regulation.Repression of alpha-actinin SM exon splicing by assisted binding of PTB to the polypyrimidine tract.Does distance matter? Variations in alternative 3' splicing regulation.Genomic functions of U2AF in constitutive and regulated splicing.Stoichiometries of U2AF35, U2AF65 and U2 snRNP reveal new early spliceosome assembly pathways.A nonsense exon in the Tpm1 gene is silenced by hnRNP H and F.RBM5 promotes exon 4 skipping of AID pre-mRNA by competing with the binding of U2AF65 to the polypyrimidine tract.Matrin3 binds directly to intronic pyrimidine-rich sequences and controls alternative splicing.Identification of novel PANDAR protein interaction partners involved in splicing regulation.Polypyrimidine tract binding protein homologs from Arabidopsis are key regulators of alternative splicing with implications in fundamental developmental processes.In vitro iCLIP-based modeling uncovers how the splicing factor U2AF2 relies on regulation by cofactors.
P2860
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P2860
The polypyrimidine tract binding protein (PTB) represses splicing of exon 6B from the beta-tropomyosin pre-mRNA by directly interfering with the binding of the U2AF65 subunit
description
2006 nî lūn-bûn
@nan
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
The polypyrimidine tract bindi ...... binding of the U2AF65 subunit
@ast
The polypyrimidine tract bindi ...... binding of the U2AF65 subunit
@en
type
label
The polypyrimidine tract bindi ...... binding of the U2AF65 subunit
@ast
The polypyrimidine tract bindi ...... binding of the U2AF65 subunit
@en
prefLabel
The polypyrimidine tract bindi ...... binding of the U2AF65 subunit
@ast
The polypyrimidine tract bindi ...... binding of the U2AF65 subunit
@en
P2860
P356
P1476
The polypyrimidine tract bindi ...... binding of the U2AF65 subunit
@en
P2093
Alain Expert-Bezançon
Joëlle Marie
P2860
P304
P356
10.1128/MCB.00893-06
P407
P577
2006-09-18T00:00:00Z