The NS1 gene contributes to the virulence of H5N1 avian influenza viruses
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A single mutation in the PB1-F2 of H5N1 (HK/97) and 1918 influenza A viruses contributes to increased virulenceMutations within the conserved NS1 nuclear export signal lead to inhibition of influenza A virus replicationViral Interactions with PDZ Domain-Containing Proteins-An Oncogenic Trait?Natural history of highly pathogenic avian influenza H5N1Nucleocytoplasmic shuttling of influenza A virus proteinsEmergence and pandemic potential of swine-origin H1N1 influenza virusContinued evolution of H5N1 influenza viruses in wild birds, domestic poultry, and humans in China from 2004 to 2009.The novel human influenza A(H7N9) virus is naturally adapted to efficient growth in human lung tissue.Newcastle disease virus-based live attenuated vaccine completely protects chickens and mice from lethal challenge of homologous and heterologous H5N1 avian influenza viruses.Avian and 1918 Spanish influenza a virus NS1 proteins bind to Crk/CrkL Src homology 3 domains to activate host cell signaling.Progress in identifying virulence determinants of the 1918 H1N1 and the Southeast Asian H5N1 influenza A viruses.Pathogenesis of 1918 pandemic and H5N1 influenza virus infections in a guinea pig model: antiviral potential of exogenous alpha interferon to reduce virus sheddingInterplay between influenza A virus and host factors: targets for antiviral intervention.Molecular pathogenesis of H5 highly pathogenic avian influenza: the role of the haemagglutinin cleavage site motifH5N1 influenza viruses: outbreaks and biological propertiesIdentification of amino acids in HA and PB2 critical for the transmission of H5N1 avian influenza viruses in a mammalian hostA Novel H1N2 Influenza Virus Related to the Classical and Human Influenza Viruses from Pigs in Southern ChinaPandemic influenza A (H1N1) virus infection and avian influenza A (H5N1) virus infection: a comparative analysis.Characterization of Clade 7.2 H5 Avian Influenza Viruses That Continue To Circulate in Chickens in ChinaGlycosylation of the Hemagglutinin Protein of H5N1 Influenza Virus Increases Its Virulence in Mice by Exacerbating the Host Immune Response.A(H5N1) Virus Evolution in South East Asia.Avian influenza (H5N1) virus of clade 2.3.2 in domestic poultry in IndiaPhylogenetic and pathogenic analyses of avian influenza A H5N1 viruses isolated from poultry in Vietnam.Genetic Analysis of Avian Influenza Viruses: Cocirculation of Avian Influenza Viruses with Allele A and B Nonstructural Gene in Northern Pintail (Anas acuta) Ducks Wintering in JapanReassortment of NS segments modifies highly pathogenic avian influenza virus interaction with avian hosts and host cells.Highly pathogenic H5N1 influenza viruses carry virulence determinants beyond the polybasic hemagglutinin cleavage site.The special neuraminidase stalk-motif responsible for increased virulence and pathogenesis of H5N1 influenza A virus.Detection of mammalian virulence determinants in highly pathogenic avian influenza H5N1 viruses: multivariate analysis of published data.The NS segment of an H5N1 highly pathogenic avian influenza virus (HPAIV) is sufficient to alter replication efficiency, cell tropism, and host range of an H7N1 HPAIVThe HA and NS genes of human H5N1 influenza A virus contribute to high virulence in ferrets.Molecular characterization of avian influenza H5N1 virus in Egypt and the emergence of a novel endemic subclade.Association of RIG-I with innate immunity of ducks to influenzaHigh interferon type I responses in the lung, plasma and spleen during highly pathogenic H5N1 infection of chicken.Host cytokine responses of pigeons infected with highly pathogenic Thai avian influenza viruses of subtype H5N1 isolated from wild birdsFull genome comparison and characterization of avian H10 viruses with different pathogenicity in Mink (Mustela vison) reveals genetic and functional differences in the non-structural gene.Characterization of Variations in PB2, NS1, M, Neuraminidase and Hemagglutinin of Influenza A (H3N2) Viruses in IranMultifunctional adaptive NS1 mutations are selected upon human influenza virus evolution in the mouse.PB2 and hemagglutinin mutations are major determinants of host range and virulence in mouse-adapted influenza A virusVirulence determinants of avian H5N1 influenza A virus in mammalian and avian hosts: role of the C-terminal ESEV motif in the viral NS1 protein.Mouse-adapted H9N2 influenza A virus PB2 protein M147L and E627K mutations are critical for high virulence.
P2860
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P2860
The NS1 gene contributes to the virulence of H5N1 avian influenza viruses
description
2006 nî lūn-bûn
@nan
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
The NS1 gene contributes to the virulence of H5N1 avian influenza viruses
@ast
The NS1 gene contributes to the virulence of H5N1 avian influenza viruses
@en
type
label
The NS1 gene contributes to the virulence of H5N1 avian influenza viruses
@ast
The NS1 gene contributes to the virulence of H5N1 avian influenza viruses
@en
prefLabel
The NS1 gene contributes to the virulence of H5N1 avian influenza viruses
@ast
The NS1 gene contributes to the virulence of H5N1 avian influenza viruses
@en
P2093
P2860
P356
P1433
P1476
The NS1 gene contributes to the virulence of H5N1 avian influenza viruses
@en
P2093
Aiqin Wang
Fengju Zhao
Guobin Tian
Hualan Chen
Kangzhen Yu
Xijun Wang
Yongping Jiang
P2860
P304
11115-11123
P356
10.1128/JVI.00993-06
P407
P50
P577
2006-09-13T00:00:00Z