Diminished production of monocyte proinflammatory cytokines during human immunodeficiency virus viremia is mediated by type I interferons
about
Human HERC5 restricts an early stage of HIV-1 assembly by a mechanism correlating with the ISGylation of GagA plasma biomarker signature of immune activation in HIV patients on antiretroviral therapySialoadhesin expressed on IFN-induced monocytes binds HIV-1 and enhances infectivity.Variability in drug metabolizing enzyme activity in HIV-infected patients.Monocyte activation in HIV/HCV coinfection correlates with cognitive impairment.Interferon-alpha drives monocyte gene expression in chronic unsuppressed HIV-1 infection.IL-27-induced gene expression is downregulated in HIV-infected subjects.Interferon-α is the primary plasma type-I IFN in HIV-1 infection and correlates with immune activation and disease markers.The macrophage: the intersection between HIV infection and atherosclerosis.Shift in monocyte apoptosis with increasing viral load and change in apoptosis-related ISG/Bcl2 family gene expression in chronically HIV-1-infected subjects.HIV-1 and recombinant gp120 affect the survival and differentiation of human vessel wall-derived mesenchymal stem cells.Human immunodeficiency virus viremia induces plasmacytoid dendritic cell activation in vivo and diminished alpha interferon production in vitro.Virus-encoded TLR ligands reveal divergent functional responses of mononuclear phagocytes in pathogenic simian immunodeficiency virus infection.A curated transcriptome dataset collection to investigate the immunobiology of HIV infection.Innate immune reconstitution with suppression of HIV-1.HIV infection-associated immune activation occurs by two distinct pathways that differentially affect CD4 and CD8 T cells.SIV infection of rhesus macaques differentially impacts mononuclear phagocyte responses to virus-derived TLR agonists.Desensitization to type I interferon in HIV-1 infection correlates with markers of immune activation and disease progression.TLR2 and TLR4 triggering exerts contrasting effects with regard to HIV-1 infection of human dendritic cells and subsequent virus transfer to CD4+ T cells.Prolonged activation of innate antiviral gene signature after childbirth is determined by IFNL3 genotypeDefective human immunodeficiency virus-specific CD8+ T-cell polyfunctionality, proliferation, and cytotoxicity are not restored by antiretroviral therapy.Circulating monocytes in HIV-1-infected viremic subjects exhibit an antiapoptosis gene signature and virus- and host-mediated apoptosis resistance.Transcriptome analysis of primary monocytes from HIV-positive patients with differential responses to antiretroviral therapy.Differential gene expression in HIV-infected individuals following ART.Stimulation of PBMC and Monocyte-Derived Macrophages via Toll-Like Receptor Activates Innate Immune Pathways in HIV-Infected Patients on Virally Suppressive Combination Antiretroviral TherapyCognitive consequences of a sustained monocyte type 1 IFN response in HIV-1 infectionEffect of type-I interferon on retroviruses.Inflammation and pharmacokinetics: potential implications for HIV-infection.A curated compendium of monocyte transcriptome datasets of relevance to human monocyte immunobiology research.SERPING1 mRNA overexpression in monocytes from HIV+ patients.Transcriptomic meta-analysis identifies gene expression characteristics in various samples of HIV-infected patients with nonprogressive disease.Monocyte exosomes induce adhesion molecules and cytokines via activation of NF-κB in endothelial cells.HIV Infection and TLR Signalling in the Liver.Transcriptome analysis of monocyte-HIV interactions.Human β defensin-3 induces chemokines from monocytes and macrophages: diminished activity in cells from HIV-infected persons.Inflammation investigated as a source of pharmacokinetic variability of atazanavir in AIDS Clinical Trials Group protocol A5224s.HBV and HIV viral load but not microbial translocation or immune activation are associated with liver fibrosis among patients in South Africa.Biomarker Identification from RNA-Seq Data using a Robust Statistical Approach.HIV-1 and the macrophageHigh Cellular Monocyte Activation in People Living With Human Immunodeficiency Virus on Combination Antiretroviral Therapy and Lifestyle-Matched Controls Is Associated With Greater Inflammation in Cerebrospinal Fluid
P2860
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P2860
Diminished production of monocyte proinflammatory cytokines during human immunodeficiency virus viremia is mediated by type I interferons
description
2006 nî lūn-bûn
@nan
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Diminished production of monoc ...... mediated by type I interferons
@ast
Diminished production of monoc ...... mediated by type I interferons
@en
type
label
Diminished production of monoc ...... mediated by type I interferons
@ast
Diminished production of monoc ...... mediated by type I interferons
@en
prefLabel
Diminished production of monoc ...... mediated by type I interferons
@ast
Diminished production of monoc ...... mediated by type I interferons
@en
P2093
P2860
P356
P1433
P1476
Diminished production of monoc ...... mediated by type I interferons
@en
P2093
Alison J Johnson
Christiana Iyasere
Joann M Mican
John C Tilton
Joseph W Adelsberger
Julia A Metcalf
Mark Connors
Marlise R Luskin
Mary McLaughlin
P2860
P304
11486-11497
P356
10.1128/JVI.00324-06
P407
P577
2006-09-27T00:00:00Z