Dasatinib targets B-lineage cells but does not provide an effective therapy for myeloproliferative disease in c-Cbl RING finger mutant mice.
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Casitas B-cell lymphoma (Cbl) proteins protect mammary epithelial cells from proteotoxicity of active c-Src accumulation.Structural Determinants of the Gain-of-Function Phenotype of Human Leukemia-associated Mutant CBL Oncogene.Tyrosine kinase inhibitor therapy-induced changes in humoral immunity in patients with chronic myeloid leukemia.Loss of Cbl and Cbl-b ubiquitin ligases abrogates hematopoietic stem cell quiescence and sensitizes leukemic disease to chemotherapy.CBL family E3 ubiquitin ligases control JAK2 ubiquitination and stability in hematopoietic stem cells and myeloid malignancies.Acquired expression of CblQ367P in mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia.
P2860
Dasatinib targets B-lineage cells but does not provide an effective therapy for myeloproliferative disease in c-Cbl RING finger mutant mice.
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2014 nî lūn-bûn
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2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2014 թվականի ապրիլին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年论文
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name
Dasatinib targets B-lineage ce ...... c-Cbl RING finger mutant mice.
@ast
Dasatinib targets B-lineage ce ...... c-Cbl RING finger mutant mice.
@en
type
label
Dasatinib targets B-lineage ce ...... c-Cbl RING finger mutant mice.
@ast
Dasatinib targets B-lineage ce ...... c-Cbl RING finger mutant mice.
@en
prefLabel
Dasatinib targets B-lineage ce ...... c-Cbl RING finger mutant mice.
@ast
Dasatinib targets B-lineage ce ...... c-Cbl RING finger mutant mice.
@en
P2093
P2860
P1433
P1476
Dasatinib targets B-lineage ce ...... c-Cbl RING finger mutant mice.
@en
P2093
Christine B F Thien
Johanna M Duyvestyn
Marlene Orandle
Samantha A Dagger
Wallace Y Langdon
P2860
P304
P356
10.1371/JOURNAL.PONE.0094717
P407
P577
2014-04-09T00:00:00Z