Defects in the Bcl-2-regulated apoptotic pathway lead to preferential increase of CD25 low Foxp3+ anergic CD4+ T cells.
about
Regulation of Bim in Health and DiseaseBim regulates alloimmune-mediated vascular injury through effects on T-cell activation and death.Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3⁺ regulatory T cellsT cell-specific inhibition of multiple apoptotic pathways blocks negative selection and causes autoimmunityFoxp3 transcription factor is proapoptotic and lethal to developing regulatory T cells unless counterbalanced by cytokine survival signalsProapoptotic protein Bim is differentially required during thymic clonal deletion to ubiquitous versus tissue-restricted antigens.Defective cell death signalling along the Bcl-2 regulated apoptosis pathway compromises Treg cell development and limits their functionality in miceThe BH3-only proteins Bim and Puma cooperate to impose deletional tolerance of organ-specific antigens.IL-15 Fosters Age-Driven Regulatory T Cell Accrual in the Face of Declining IL-2 Levels.Serum amyloid A inhibits dendritic cell apoptosis to induce glucocorticoid resistance in CD4(+) T cells.Hyperlipidemia Alters Regulatory T Cell Function and Promotes Resistance to Tolerance Induction Through Costimulatory Molecule Blockade.Thymocyte apoptosis drives the intrathymic generation of regulatory T cells.Getting away with murder: how does the BCL-2 family of proteins kill with immunity?Cell death and thymic tolerance.IL-2 prevents deletion of developing T-regulatory cells in the thymus.The life and death of immune cell types: the role of BCL-2 anti-apoptotic molecules.Loss of BIM increases mitochondrial oxygen consumption and lipid oxidation, reduces adiposity and improves insulin sensitivity in mice.Nur77 Regulates Nondeletional Mechanisms of Tolerance in T Cells.Exacerbation of spontaneous autoimmune nephritis following regulatory T cell depletion in B cell lymphoma 2-interacting mediator knock-out mice.A timeline demarcating two waves of clonal deletion and Foxp3 upregulation during thymocyte development.
P2860
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P2860
Defects in the Bcl-2-regulated apoptotic pathway lead to preferential increase of CD25 low Foxp3+ anergic CD4+ T cells.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Defects in the Bcl-2-regulated ...... w Foxp3+ anergic CD4+ T cells.
@ast
Defects in the Bcl-2-regulated ...... w Foxp3+ anergic CD4+ T cells.
@en
type
label
Defects in the Bcl-2-regulated ...... w Foxp3+ anergic CD4+ T cells.
@ast
Defects in the Bcl-2-regulated ...... w Foxp3+ anergic CD4+ T cells.
@en
prefLabel
Defects in the Bcl-2-regulated ...... w Foxp3+ anergic CD4+ T cells.
@ast
Defects in the Bcl-2-regulated ...... w Foxp3+ anergic CD4+ T cells.
@en
P2093
P2860
P50
P356
P1476
Defects in the Bcl-2-regulated ...... w Foxp3+ anergic CD4+ T cells.
@en
P2093
Emma M Carrington
Hyun-Ja Ko
Ian P Wicks
Lorraine O'Reilly
Yuxia Zhang
P2860
P304
P356
10.4049/JIMMUNOL.1100027
P407
P577
2011-07-08T00:00:00Z