Oligomerization of MDC1 protein is important for proper DNA damage response - Wikidata - awgldk - TriplyDB

Oligomerization of MDC1 protein is important for proper DNA damage response

Oligomerization of MDC1 protein is important for proper DNA damage response

http://www.wikidata.org/entity/Q35150138

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Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator Dimerization, but not phosphothreonine binding, is conserved between the forkhead-associated domains of Drosophila MU2 and human MDC1 Multifunctional role of ATM/Tel1 kinase in genome stability: from the DNA damage response to telomere maintenance Bufalin induces cell death in human lung cancer cells through disruption of DNA damage response pathways.53BP1 mediates the fusion of mammalian telomeres rendered dysfunctional by DNA-PKcs loss or inhibition.Dimerization Mediated by a Divergent Forkhead-associated Domain Is Essential for the DNA Damage and Spindle Functions of Fission Yeast Mdb1.DNA damage sensing by the ATM and ATR kinases.The nucleosome: orchestrating DNA damage signaling and repair within chromatin.Phenotypic Analysis of ATM Protein Kinase in DNA Double-Strand Break Formation and Repair.

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Oligomerization of MDC1 protein is important for proper DNA damage response

http://www.wikidata.org/entity/Q35150138

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2011 nî lūn-bûn

@nan

2011 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Oligomerization of MDC1 protein is important for proper DNA damage response

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Oligomerization of MDC1 protein is important for proper DNA damage response

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type

label

Oligomerization of MDC1 protein is important for proper DNA damage response

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Oligomerization of MDC1 protein is important for proper DNA damage response

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prefLabel

Oligomerization of MDC1 protein is important for proper DNA damage response

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Oligomerization of MDC1 protein is important for proper DNA damage response

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JBC.M111.258087

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Journal of Biological Chemistry

P1476

Oligomerization of MDC1 protein is important for proper DNA damage response

@en

P2093

Jian Yuan

http://www.w3.org/2001/XMLSchema#string

Kuntian Luo

http://www.w3.org/2001/XMLSchema#string

Zhenkun Lou

http://www.w3.org/2001/XMLSchema#string

P2860

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

ATM-dependent phosphorylation of nibrin in response to radiation exposure

MDC1 is a mediator of the mammalian DNA damage checkpoint

MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks

RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly

Phospho-dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage

Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase

Megabase chromatin domains involved in DNA double-strand breaks in vivo

The molecular basis of FHA domain:phosphopeptide binding specificity and implications for phospho-dependent signaling mechanisms

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28192-28199

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scholarly article

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10.1074/JBC.M111.258087

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32

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286

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