Mutant activated FGFR3 impairs endochondral bone growth by preventing SOX9 downregulation in differentiating chondrocytes
about
Fibroblast growth factor signaling in skeletal development and diseaseThe transcription factors SOX9 and SOX5/SOX6 cooperate genome-wide through super-enhancers to drive chondrogenesisThe SOX9 upstream region prone to chromosomal aberrations causing campomelic dysplasia contains multiple cartilage enhancers.Tyrosine kinase inhibitor NVP-BGJ398 functionally improves FGFR3-related dwarfism in mouse model.Developmental Regulation of the Growth Plate and Cranial Synchondrosis.Achondroplasia: Development, pathogenesis, and therapy.Chondrocyte FGFR3 Regulates Bone Mass by Inhibiting Osteogenesis.HDAC6 deficiency or inhibition blocks FGFR3 accumulation and improves bone growth in a model of achondroplasia.
P2860
Q26798215-C94AAD13-42C1-4DF6-BC64-C8D1CED7487EQ34483803-43925389-8E5A-4D70-8104-6389D2FE7133Q35770634-D02707A4-8ACF-44C7-A2FC-3EA7AF5FC860Q36867279-71A1DE35-B810-4BF7-A3F4-39C73C70C2E8Q38850528-1106CAF4-6644-4C7A-B2BB-FF6FAC9244CCQ39041957-A654D5C9-55DC-457D-AC17-A4F37CD35FA8Q47199241-6AC0B46F-9B97-4AD2-9E8D-0A4EC81AF0F0Q50493259-52BA341B-DBD3-4357-9B1B-7122209BD605
P2860
Mutant activated FGFR3 impairs endochondral bone growth by preventing SOX9 downregulation in differentiating chondrocytes
description
2014 nî lūn-bûn
@nan
2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Mutant activated FGFR3 impairs ...... n differentiating chondrocytes
@en
type
label
Mutant activated FGFR3 impairs ...... n differentiating chondrocytes
@en
prefLabel
Mutant activated FGFR3 impairs ...... n differentiating chondrocytes
@en
P2093
P2860
P356
P1476
Mutant activated FGFR3 impairs ...... n differentiating chondrocytes
@en
P2093
Chuxia Deng
Haruhiko Akiyama
Peter J Hurlin
Zi-Qiang Zhou
P2860
P304
P356
10.1093/HMG/DDU594
P577
2014-11-28T00:00:00Z