Regulation of oxidative stress-induced calcium release by phosphatidylinositol 3-kinase and Bruton's tyrosine kinase in B cells.
about
Tyrosine residues in phospholipase Cgamma 2 essential for the enzyme function in B-cell signalingTec kinases mediate sustained calcium influx via site-specific tyrosine phosphorylation of the phospholipase Cgamma Src homology 2-Src homology 3 linker.The major target of the endogenously generated reactive oxygen species in response to insulin stimulation is phosphatase and tensin homolog and not phosphoinositide-3 kinase (PI-3 kinase) in the PI-3 kinase/Akt pathwayPhosphoinositide 3-kinase regulates plasma membrane targeting of the Ras-specific exchange factor RasGRP1.Benzodiazepine-induced superoxide signals B cell apoptosis: mechanistic insight and potential therapeutic utility.Suofu Qin's work on studies of cell survival signaling in cancer and epithelial cells.Cellular protection using Flt3 and PI3Kα inhibitors demonstrates multiple mechanisms of oxidative glutamate toxicity.The antidiabetic compound 2-dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione, isolated from Averrhoa carambola L., demonstrates significant antitumor potential against human breast cancer cells.Role of initial protein phosphorylation events and localized release-activated calcium influx in B cell antigen receptor signaling.Regulation of ras exchange factors and cellular localization of ras activation by lipid messengers in T cells.Thiol alkylation inhibits the mitogenic effects of platelet-derived growth factor and renders it proapoptotic via activation of STATs and p53 and induction of expression of caspase1 and p21(waf1/cip1).Calcium alterations signal either to senescence or to autophagy induction in stem cells upon oxidative stress.A targeted mass spectrometric analysis of phosphatidylinositol phosphate species.Requirements for distinct steps of phospholipase Cgamma2 regulation, membrane-raft-dependent targeting and subsequent enzyme activation in B-cell signalling.Transcriptional profile of breast muscle in heat stressed layers is similar to that of broiler chickens at control temperature.Biphasic effects of H(2)O(2) on BK(Ca) channels.A novel peroxide-induced calcium transient regulates interleukin-6 expression in cardiac-derived fibroblasts.Tyrosine phosphorylation of I kappa B alpha activates NF kappa B through a redox-regulated and c-Src-dependent mechanism following hypoxia/reoxygenation.A novel benzodiazepine increases the sensitivity of B cells to receptor stimulation with synergistic effects on calcium signaling and apoptosis.REQUIREMENT OF THE TEC FAMILY TYROSINE KINASE BTK29A FOR COURTSHIP MEMORY IN Drosophila MALES.
P2860
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P2860
Regulation of oxidative stress-induced calcium release by phosphatidylinositol 3-kinase and Bruton's tyrosine kinase in B cells.
description
2000 nî lūn-bûn
@nan
2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Regulation of oxidative stress ...... 's tyrosine kinase in B cells.
@ast
Regulation of oxidative stress ...... 's tyrosine kinase in B cells.
@en
type
label
Regulation of oxidative stress ...... 's tyrosine kinase in B cells.
@ast
Regulation of oxidative stress ...... 's tyrosine kinase in B cells.
@en
prefLabel
Regulation of oxidative stress ...... 's tyrosine kinase in B cells.
@ast
Regulation of oxidative stress ...... 's tyrosine kinase in B cells.
@en
P2093
P2860
P356
P1476
Regulation of oxidative stress ...... 's tyrosine kinase in B cells.
@en
P2093
P2860
P304
P356
10.1073/PNAS.130198197
P407
P577
2000-06-01T00:00:00Z