The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease - Wikidata - awgldk - TriplyDB

The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease

The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease

http://www.wikidata.org/entity/Q35155012

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Nutritional and Nanotechnological Modulators of Microglia The Therapeutic Potential of the Ketogenic Diet in Treating Progressive Multiple Sclerosis Interleukin-1 Family Cytokines in Liver Diseases Inflammasomes: mechanism of action, role in disease, and therapeutics NLRP3 inflammasome and its inhibitors: a review Tumor Metabolism, the Ketogenic Diet and β-Hydroxybutyrate: Novel Approaches to Adjuvant Brain Tumor Therapy Regulation of Ketone Body Metabolism and the Role of PPARα Regulation of Nlrp3 inflammasome by dietary metabolites Inflammasomes and Natural Ingredients towards New Anti-Inflammatory Agents Immune Cell Regulatory Pathways Unexplored as Host-Directed Therapeutic Targets for Mycobacterium tuberculosis: An Opportunity to Apply Precision Medicine Innovations to Infectious Diseases Paradoxical changes in innate immunity in aging: recent progress and new directions Drivers of age-related inflammation and strategies for healthspan extension NLRP3 Inflammasome in Neurological Diseases, from Functions to Therapies The Crosstalk between the Gut Microbiota and Mitochondria during Exercise.Targeting the deubiquitinase STAMBP inhibits NALP7 inflammasome activity.Potential of IL-1, IL-18 and Inflammasome Inhibition for the Treatment of Inflammatory Skin Diseases.Bidirectional communication between the Aryl hydrocarbon Receptor (AhR) and the microbiome tunes host metabolism.Complementing the inflammasome.Editorial: Can GPR43 Sensing of Short-Chain Fatty Acids Unchain Inflammasome-Driven Arthritis?Immune aging, dysmetabolism, and inflammation in neurological diseases.Ketone bodies mediate antiseizure effects through mitochondrial permeability transition.Shikonin Suppresses NLRP3 and AIM2 Inflammasomes by Direct Inhibition of Caspase-1.GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells.Plasma Metabolites Predict Severity of Depression and Suicidal Ideation in Psychiatric Patients-A Multicenter Pilot Analysis β-Hydroxybutyrate Deactivates Neutrophil NLRP3 Inflammasome to Relieve Gout Flares.Ketogenic diet improves the spatial memory impairment caused by exposure to hypobaric hypoxia through increased acetylation of histones in rats Fasting and refeeding differentially regulate NLRP3 inflammasome activation in human subjects.Genipin inhibits NLRP3 and NLRC4 inflammasome activation via autophagy suppression.Macrophage functions in lean and obese adipose tissue.Macrophage-specific de Novo Synthesis of Ceramide Is Dispensable for Inflammasome-driven Inflammation and Insulin Resistance in Obesity.Metabolite Regulation of Nuclear Localization of Carbohydrate-response Element-binding Protein (ChREBP): ROLE OF AMP AS AN ALLOSTERIC INHIBITOR Partial Amelioration of Peripheral and Central Symptoms of Huntington's Disease via Modulation of Lipid Metabolism.Prevalence of ketosis, ketonuria, and ketoacidosis during liberal glycemic control in critically ill patients with diabetes: an observational study.A novel "complement-metabolism-inflammasome axis" as a key regulator of immune cell effector function Targeting ASC in NLRP3 inflammasome by caffeic acid phenethyl ester: a novel strategy to treat acute gout.NOX4-dependent fatty acid oxidation promotes NLRP3 inflammasome activation in macrophages.NLRP3 inflammasome: Pathogenic role and potential therapeutic target for IgA nephropathy.Carnitine acetyltransferase (CRAT) expression in macrophages is dispensable for nutrient stress sensing and inflammation.β-Hydroxybutyrate suppresses inflammasome formation by ameliorating endoplasmic reticulum stress via AMPK activation Inhibition of NLRP3 Inflammasome Pathway by Butyrate Improves Corneal Wound Healing in Corneal Alkali Burn.

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P2860

The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease

http://www.wikidata.org/entity/Q35155012

description

2015 nî lūn-bûn

@nan

2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2015 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2015年の論文

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2015年論文

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2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

name

The ketone metabolite β-hydrox ...... -mediated inflammatory disease

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The ketone metabolite β-hydrox ...... -mediated inflammatory disease

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type

label

The ketone metabolite β-hydrox ...... -mediated inflammatory disease

@ast

The ketone metabolite β-hydrox ...... -mediated inflammatory disease

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prefLabel

The ketone metabolite β-hydrox ...... -mediated inflammatory disease

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The ketone metabolite β-hydrox ...... -mediated inflammatory disease

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Nature Medicine

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The ketone metabolite β-hydrox ...... -mediated inflammatory disease

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P2093

Arya Biragyn

http://www.w3.org/2001/XMLSchema#string

Christopher Lupfer

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Dominic D'Agostino

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Emad Alnemri

http://www.w3.org/2001/XMLSchema#string

Emily L Goldberg

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Kim Y Nguyen

http://www.w3.org/2001/XMLSchema#string

Noah Planavsky

http://www.w3.org/2001/XMLSchema#string

Seokwon Kang

http://www.w3.org/2001/XMLSchema#string

Tamas L Horvath

http://www.w3.org/2001/XMLSchema#string

Tarek M Fahmy

http://www.w3.org/2001/XMLSchema#string

P2860

Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes.

NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice

Gout-associated uric acid crystals activate the NALP3 inflammasome

Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes.

Activation and regulation of the inflammasomes

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

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263-269

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scholarly article

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10.1038/NM.3804

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3

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21

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Thirumala-Devi Kanneganti

Peter A Crawford

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2015-02-16T00:00:00Z

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272354552

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