APOBEC3B expression in breast cancer reflects cellular proliferation, while a deletion polymorphism is associated with immune activation.
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Tumor-intrinsic oncogene pathways mediating immune avoidanceAPOBEC3B, a molecular driver of mutagenesis in human cancers.Structural determinants of APOBEC3B non-catalytic domain for molecular assembly and catalytic regulationDNA replication stress: a source of APOBEC3B expression in breast cancerAPOBEC Enzymes: Mutagenic Fuel for Cancer Evolution and Heterogeneity.Mutation Processes in 293-Based Clones Overexpressing the DNA Cytosine Deaminase APOBEC3B.The 29.5 kb APOBEC3B Deletion Polymorphism Is Not Associated with Clinical Outcome of Breast Cancer.An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancersThe eQTL-missense polymorphisms of APOBEC3H are associated with lung cancer risk in a Han Chinese population.DNA cytosine and methylcytosine deamination by APOBEC3B: enhancing methylcytosine deamination by engineering APOBEC3B.Expression of APOBEC3B mRNA in Primary Breast Cancer of Japanese Women.The PKC/NF-κB signaling pathway induces APOBEC3B expression in multiple human cancers.Progressive APOBEC3B mRNA expression in distant breast cancer metastases.Crystal Structure of the DNA Deaminase APOBEC3B Catalytic Domain.Effect of apolipoprotein B mRNA-editing catalytic polypeptide-like protein-3G in cervical cancerIntegrative genomic analysis reveals functional diversification of APOBEC gene family in breast cancer.APOBEC-induced mutations in human cancers are strongly enriched on the lagging DNA strand during replication.Germline APOBEC3B deletion is associated with breast cancer risk in an Asian multi-ethnic cohort and with immune cell presentation.Nuclear Magnetic Resonance Structure of the APOBEC3B Catalytic Domain: Structural Basis for Substrate Binding and DNA Deaminase Activity.The DNA cytosine deaminase APOBEC3H haplotype I likely contributes to breast and lung cancer mutagenesis.Leveraging premalignant biology for immune-based cancer prevention.The DNA cytosine deaminase APOBEC3B promotes tamoxifen resistance in ER-positive breast cancer.Reactivation of dormant anti-tumor immunity - a clinical perspective of therapeutic immune checkpoint modulation.Risks at the DNA Replication Fork: Effects upon Carcinogenesis and Tumor HeterogeneityStructural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B.Degradation of the cancer genomic DNA deaminase APOBEC3B by SIV VifWeSME: uncovering mutual exclusivity of cancer drivers and beyond.Increased APOBEC3B Predicts Worse Outcomes in Lung Cancer: A Comprehensive Retrospective StudyAPOBEC3G Expression Correlates with T-Cell Infiltration and Improved Clinical Outcomes in High-grade Serous Ovarian CarcinomaAPOBEC3A is an oral cancer prognostic biomarker in Taiwanese carriers of an APOBEC deletion polymorphism.Roles of APOBEC3A and APOBEC3B in Human Papillomavirus Infection and Disease Progression.Heat shock proteins stimulate APOBEC-3-mediated cytidine deamination in the hepatitis B virus.Assessment of an APOBEC3B truncating mutation, c.783delG, in patients with breast cancer.APOBEC3B is an enzymatic source of molecular alterations in esophageal squamous cell carcinoma.p53 controls expression of the DNA deaminase APOBEC3B to limit its potential mutagenic activity in cancer cells.APOBEC Enzymes as Targets for Virus and Cancer Therapy.Conformational Switch Regulates the DNA Cytosine Deaminase Activity of Human APOBEC3B.The 30 kb deletion in the APOBEC3 cluster decreases APOBEC3A and APOBEC3B expression and creates a transcriptionally active hybrid gene but does not associate with breast cancer in the European population.Viral subversion of APOBEC3s: Lessons for anti-tumor immunity and tumor immunotherapy.Correlation of gene expression and associated mutation profiles of APOBEC3A, APOBEC3B, REV1, UNG, and FHIT with chemosensitivity of cancer cell lines to drug treatment.
P2860
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P2860
APOBEC3B expression in breast cancer reflects cellular proliferation, while a deletion polymorphism is associated with immune activation.
description
2015 nî lūn-bûn
@nan
2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
APOBEC3B expression in breast ...... ciated with immune activation.
@ast
APOBEC3B expression in breast ...... ciated with immune activation.
@en
type
label
APOBEC3B expression in breast ...... ciated with immune activation.
@ast
APOBEC3B expression in breast ...... ciated with immune activation.
@en
prefLabel
APOBEC3B expression in breast ...... ciated with immune activation.
@ast
APOBEC3B expression in breast ...... ciated with immune activation.
@en
P2860
P356
P1476
APOBEC3B expression in breast ...... ciated with immune activation.
@en
P2093
David W Cescon
P2860
P304
P356
10.1073/PNAS.1424869112
P407
P577
2015-02-17T00:00:00Z