Functional cdc25C dual-specificity phosphatase is required for S-phase entry in human cells.
about
Androgens upregulate Cdc25C protein by inhibiting its proteasomal and lysosomal degradation pathwaysSD-208, a novel protein kinase D inhibitor, blocks prostate cancer cell proliferation and tumor growth in vivo by inducing G2/M cell cycle arrestDistinct pools of cdc25C are phosphorylated on specific TP sites and differentially localized in human mitotic cellsRecurrent CDC25C mutations drive malignant transformation in FPD/AML.Unscheduled expression of CDC25B in S-phase leads to replicative stress and DNA damage.Contributions made by CDC25 phosphatases to proliferation of intestinal epithelial stem and progenitor cellsHow adeno-associated virus Rep78 protein arrests cells completely in S phaseTranscriptional regulation of adipocyte differentiation: a central role for CCAAT/enhancer-binding protein (C/EBP) β.Coffee extract inhibits adipogenesis in 3T3-L1 preadipocyes by interrupting insulin signaling through the downregulation of IRS1Novel mechanism of harmaline on inducing G2/M cell cycle arrest and apoptosis by up-regulating Fas/FasL in SGC-7901 cells.Histone demethylase Kdm4b functions as a co-factor of C/EBPβ to promote mitotic clonal expansion during differentiation of 3T3-L1 preadipocytes.The interaction of herpes simplex virus 1 regulatory protein ICP22 with the cdc25C phosphatase is enabled in vitro by viral protein kinases US3 and UL13.CDC25 phosphatases in cancer cells: key players? Good targets?G1 to S phase cell cycle transition in somatic and embryonic stem cells.In vivo roles of CDC25 phosphatases: biological insight into the anti-cancer therapeutic targetsThe overexpression of KIFC1 was associated with the proliferation and prognosis of non-small cell lung cancerTherapeutic targeting the cell division cycle 25 (CDC25) phosphatases in human acute myeloid leukemia--the possibility to target several kinases through inhibition of the various CDC25 isoforms.Only Akt1 is required for proliferation, while Akt2 promotes cell cycle exit through p21 binding.Cdc25B cooperates with Cdc25A to induce mitosis but has a unique role in activating cyclin B1-Cdk1 at the centrosome.Silymarin and silibinin cause G1 and G2-M cell cycle arrest via distinct circuitries in human prostate cancer PC3 cells: a comparison of flavanone silibinin with flavanolignan mixture silymarin.Expression of CDC5L is associated with tumor progression in gliomas.Mdm2 promotes Cdc25C protein degradation and delays cell cycle progression through the G2/M phase.Transition metal dependent regulation of the signal transduction cascade driving oocyte meiosis.CDC-25.1 controls the rate of germline mitotic cell cycle by counteracting WEE-1.3 and by positively regulating CDK-1 in Caenorhabditis elegans.A caspase-dependent cleavage of CDC25A generates an active fragment activating cyclin-dependent kinase 2 during apoptosis.
P2860
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P2860
Functional cdc25C dual-specificity phosphatase is required for S-phase entry in human cells.
description
2003 nî lūn-bûn
@nan
2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի ապրիլին հրատարակված գիտական հոդված
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2003年の論文
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2003年学术文章
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2003年学术文章
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2003年学术文章
@zh-hans
2003年学术文章
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2003年学术文章
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2003年學術文章
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name
Functional cdc25C dual-specifi ...... S-phase entry in human cells.
@ast
Functional cdc25C dual-specifi ...... S-phase entry in human cells.
@en
type
label
Functional cdc25C dual-specifi ...... S-phase entry in human cells.
@ast
Functional cdc25C dual-specifi ...... S-phase entry in human cells.
@en
prefLabel
Functional cdc25C dual-specifi ...... S-phase entry in human cells.
@ast
Functional cdc25C dual-specifi ...... S-phase entry in human cells.
@en
P2093
P2860
P356
P1476
Functional cdc25C dual-specifi ...... r S-phase entry in human cells
@en
P2093
Anne Fernandez
Celine Franckhauser
Ned J C Lamb
Patric Turowski
P2860
P304
P356
10.1091/MBC.E02-08-0515
P577
2003-04-17T00:00:00Z