Molecular mechanisms of insulin receptor substrate protein-mediated modulation of insulin signalling.
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Landmarks in insulin researchA domain-oriented approach to the reduction of combinatorial complexity in signal transduction networksModulation of human insulin receptor substrate-1 tyrosine phosphorylation by protein kinase CdeltaDeletion of SOCS7 leads to enhanced insulin action and enlarged islets of Langerhans.A steady state analysis indicates that negative feedback regulation of PTP1B by Akt elicits bistability in insulin-stimulated GLUT4 translocationMolecular and biochemical trajectories from diabetes to Alzheimer's disease: A critical appraisalStructural insights into FRS2α PTB domain recognition by neurotrophin receptor TrkBThe diverse involvement of heterogeneous nuclear ribonucleoprotein K in mitochondrial response to insulinAdiposity, dyslipidemia, and insulin resistance in mice with targeted deletion of phospholipid scramblase 3 (PLSCR3)A hierarchical whole-body modeling approach elucidates the link between in Vitro insulin signaling and in Vivo glucose homeostasis.Asb6, an adipocyte-specific ankyrin and SOCS box protein, interacts with APS to enable recruitment of elongins B and C to the insulin receptor signaling complex.Regulation of MAP kinase-directed mitogenic and protein kinase B-mediated signaling by cannabinoid receptor type 1 in skeletal muscle cellsσ-1 receptor stimulation protects against pressure-induced damage through InsR-MAPK signaling in human trabecular meshwork cellsProtein phosphatase 4 interacts with and down-regulates insulin receptor substrate 4 following tumor necrosis factor-alpha stimulation.Insulin-resistant brain state: the culprit in sporadic Alzheimer's disease?Insulin resistance and muscle insulin receptor substrate-1 serine hyperphosphorylation.A hepatocyte growth factor receptor (Met)-insulin receptor hybrid governs hepatic glucose metabolism.Turning signals on and off: GLUT4 traffic in the insulin-signaling highway.On the role of IRS2 in the regulation of functional beta-cell mass.Probiotics improve high fat diet-induced hepatic steatosis and insulin resistance by increasing hepatic NKT cells.Elevated insulin signaling disrupts the growth and differentiation pattern of the mouse lens.Systems-level interactions between insulin-EGF networks amplify mitogenic signaling.Mechanisms involved in the nutritional regulation of mRNA translation: features of the avian model.The FRS2 family of docking/scaffolding adaptor proteins as therapeutic targets of cancer treatment.Possible implications of insulin resistance and glucose metabolism in Alzheimer's disease pathogenesis.Insulin resistance: an emerging link in Alzheimer's disease.Reflections on glycogen and β-amyloid: why does glycogenolytic β2-adrenoceptor stimulation not rescue memory after β-amyloid?Grape seed proanthocyanidins and metformin act by different mechanisms to promote insulin signaling in rats fed high calorie diet.Mathematical Justification of Expression-Based Pathway Activation Scoring (PAS).CB1 receptor blockade counters age-induced insulin resistance and metabolic dysfunctionLipopolysaccharide impairs insulin sensitivity via activation of phosphoinositide 3-kinase in adipocytes.Differential activation of insulin receptor substrates 1 and 2 by insulin-like growth factor-activated insulin receptors.Muscarinic-receptor-mediated inhibition of insulin-like growth factor-1 receptor-stimulated phosphoinositide 3-kinase signalling in 1321N1 astrocytoma cells.A novel domain mediates insulin-induced proteasomal degradation of insulin receptor substrate 1 (IRS-1).Alzheimer-like changes in protein kinase B and glycogen synthase kinase-3 in rat frontal cortex and hippocampus after damage to the insulin signalling pathway.Analysis of the role of protein kinase B (cAKT) in insulin-dependent induction of glucokinase and sterol regulatory element-binding protein 1 (SREBP1) mRNAs in hepatocytes.Socs1 deficiency enhances hepatic insulin signaling.Microcystin-LR disrupts insulin signaling by hyperphosphorylating insulin receptor substrate 1 and glycogen synthase.Intranasal Insulin Administration Ameliorates Streptozotocin (ICV)-Induced Insulin Receptor Dysfunction, Neuroinflammation, Amyloidogenesis, and Memory Impairment in Rats.Brain insulin resistance accelerates Aβ fibrillogenesis by inducing GM1 ganglioside clustering in the presynaptic membranes.
P2860
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P2860
Molecular mechanisms of insulin receptor substrate protein-mediated modulation of insulin signalling.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Molecular mechanisms of insuli ...... ulation of insulin signalling.
@ast
Molecular mechanisms of insuli ...... ulation of insulin signalling.
@en
type
label
Molecular mechanisms of insuli ...... ulation of insulin signalling.
@ast
Molecular mechanisms of insuli ...... ulation of insulin signalling.
@en
prefLabel
Molecular mechanisms of insuli ...... ulation of insulin signalling.
@ast
Molecular mechanisms of insuli ...... ulation of insulin signalling.
@en
P2093
P1433
P1476
Molecular mechanisms of insuli ...... ulation of insulin signalling.
@en
P2093
Anne M Johnston
Emmanuel Van Obberghen
Luciano Pirola
P356
10.1016/S0014-5793(03)00438-1
P407
P577
2003-07-01T00:00:00Z