Solid-phase extraction and quantitative measurement of omega and omega-1 metabolites of JWH-018 and JWH-073 in human urine. - Wikidata - awgldk - TriplyDB

Solid-phase extraction and quantitative measurement of omega and omega-1 metabolites of JWH-018 and JWH-073 in human urine.

Solid-phase extraction and quantitative measurement of omega and omega-1 metabolites of JWH-018 and JWH-073 in human urine.

http://www.wikidata.org/entity/Q35164115

about

Spice drugs are more than harmless herbal blends: a review of the pharmacology and toxicology of synthetic cannabinoids Distinct pharmacology and metabolism of K2 synthetic cannabinoids compared to Δ(9)-THC: mechanism underlying greater toxicity?"Herbal incense": designer drug blends as cannabimimetics and their assessment by drug discrimination and other in vivo bioassays.Severe toxicity following synthetic cannabinoid ingestion.Detection of urinary metabolites of AM-2201 and UR-144, two novel synthetic cannabinoids.Metabolites of 5F-AKB-48, a synthetic cannabinoid receptor agonist, identified in human urine and liver microsomal preparations using liquid chromatography high-resolution mass spectrometry.UPLC/ESI-MS/MS-based determination of metabolism of several new illicit drugs, ADB-FUBINACA, AB-FUBINACA, AB-PINACA, QUPIC, 5F-QUPIC and α-PVT, by human liver microsome.Baths salts, spice, and related designer drugs: the science behind the headlines.High-resolution mass spectrometric metabolite profiling of a novel synthetic designer drug, N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indole-3-carboxamide (STS-135), using cryopreserved human hepatocytes and assessment of metabolic stability with hum Qualitative confirmation of 9 synthetic cannabinoids and 20 metabolites in human urine using LC-MS/MS and library search K2 toxicity: fatal case of psychiatric complications following AM2201 exposure.Using cheminformatics to predict cross reactivity of "designer drugs" to their currently available immunoassays.Quantitative urine confirmatory testing for synthetic cannabinoids in randomly collected urine specimens.Metabolism of RCS-8, a synthetic cannabinoid with cyclohexyl structure, in human hepatocytes by high-resolution MS.Monohydroxylated metabolites of the K2 synthetic cannabinoid JWH-073 retain intermediate to high cannabinoid 1 receptor (CB1R) affinity and exhibit neutral antagonist to partial agonist activity.Comprehensive review of the detection methods for synthetic cannabinoids and cathinones.Validation of an ELISA Synthetic Cannabinoids Urine Assay Cytochrome P450-mediated oxidative metabolism of abused synthetic cannabinoids found in K2/Spice: identification of novel cannabinoid receptor ligands.Gas chromatography-mass spectrometry of JWH-018 metabolites in urine samples with direct comparison to analytical standards Human metabolites of synthetic cannabinoids JWH-018 and JWH-073 bind with high affinity and act as potent agonists at cannabinoid type-2 receptors.Spicing things up: synthetic cannabinoids.A major glucuronidated metabolite of JWH-018 is a neutral antagonist at CB1 receptors.Simultaneous quantification of 20 synthetic cannabinoids and 21 metabolites, and semi-quantification of 12 alkyl hydroxy metabolites in human urine by liquid chromatography-tandem mass spectrometry.Recent developments in urinalysis of metabolites of new psychoactive substances using LC-MS.Synthetic cannabinoids pharmacokinetics and detection methods in biological matrices.An overview of recent developments in the analytical detection of new psychoactive substances (NPSs).Pharmacological and Toxicological Effects of Synthetic Cannabinoids and Their Metabolites.Detection Times of Carboxylic Acid Metabolites of the Synthetic Cannabinoids JWH-018 and JWH-073 in Human Urine.Analysis of Parent Synthetic Cannabinoids in Blood and Urinary Metabolites by Liquid Chromatography Tandem Mass Spectrometry.Determination of AM-2201 metabolites in urine and comparison with JWH-018 abuse.Deposition of JWH-018, JWH-073 and their metabolites in hair and effect of hair pigmentation.Strategies for ascertaining the interference of phase II metabolites co-eluting with parent compounds using LC-MS/MS.Metabolism of synthetic cannabinoids PB-22 and its 5-fluoro analog, 5F-PB-22, by human hepatocyte incubation and high-resolution mass spectrometry.A case of acute cerebral ischemia following inhalation of a synthetic cannabinoid.Identification of AKB-48 and 5F-AKB-48 Metabolites in Authentic Human Urine Samples Using Human Liver Microsomes and Time of Flight Mass Spectrometry.LC-QTOF-MS as a superior strategy to immunoassay for the comprehensive analysis of synthetic cannabinoids in urine.Simultaneous determination of herbicide residues in tobacco using ultraperformance convergence chromatography coupled with solid-phase extraction.Electrochemical simulation of phase I metabolism for 21 drugs using four different working electrodes in an automated screening setup with MS detection.A sensitive GC-EIMS method for simultaneous detection and quantification of JWH-018 and JWH-073 carboxylic acid and hydroxy metabolites in urine.Cytochrome P450-mediated metabolism of the synthetic cannabinoids UR-144 and XLR-11

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Solid-phase extraction and quantitative measurement of omega and omega-1 metabolites of JWH-018 and JWH-073 in human urine.

http://www.wikidata.org/entity/Q35164115

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2011 nî lūn-bûn

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2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2011 թվականի հուլիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年學術文章

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name

Solid-phase extraction and qua ...... 18 and JWH-073 in human urine.

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Solid-phase extraction and qua ...... 18 and JWH-073 in human urine.

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type

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Solid-phase extraction and qua ...... 18 and JWH-073 in human urine.

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Solid-phase extraction and qua ...... 18 and JWH-073 in human urine.

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Solid-phase extraction and qua ...... 18 and JWH-073 in human urine.

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Solid-phase extraction and qua ...... 18 and JWH-073 in human urine.

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Analytical Chemistry

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Solid-phase extraction and qua ...... 18 and JWH-073 in human urine.

@en

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Adam Uzieblo

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Anna Radominska-Pandya

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Cindy L Moran

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E Kim Fifer

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Gregory W Endres

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Jeff Lapoint

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Jeffery H Moran

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Krishna C Chimalakonda

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Laura P James

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Paul D Kennedy

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P2860

Structure characterisation of urinary metabolites of the cannabimimetic JWH-018 using chemically synthesised reference material for the support of LC-MS/MS-based drug testing.

Detection of JWH-018 metabolites in smoking mixture post-administration urine.

Marijuana-based drugs: innovative therapeutics or designer drugs of abuse?

Quantitative measurement of JWH-018 and JWH-073 metabolites excreted in human urine

Identification of in vitro metabolites of JWH-015, an aminoalkylindole agonist for the peripheral cannabinoid receptor (CB2) by HPLC-MS/MS.

Spice: a never ending story?

Monitoring of herbal mixtures potentially containing synthetic cannabinoids as psychoactive compounds.

Warning: legal synthetic cannabinoid-receptor agonists such as JWH-018 may precipitate psychosis in vulnerable individuals.

In vitro phase I metabolism of the synthetic cannabimimetic JWH-018.

A teenager with agitation: higher than she should have climbed.

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6381-6388

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scholarly article

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10.1021/AC201377M

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16

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83

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Robert S Hoffman

Lewis S. Nelson

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2011-07-27T00:00:00Z

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51477701

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