Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells. - Wikidata - awgldk - TriplyDB

Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells.

Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells.

http://www.wikidata.org/entity/Q35164584

about

Salinomycin as a drug for targeting human cancer stem cells A Second WNT for Old Drugs: Drug Repositioning against WNT-Dependent Cancers Anti-Cancer Stem-like Cell Compounds in Clinical Development - An Overview and Critical Appraisal Cancer stem cells--important players in tumor therapy resistance Identifying and targeting tumor-initiating cells in the treatment of breast cancer Salinomycin: a novel anti-cancer agent with known anti-coccidial activities The Valley of Death in anticancer drug development: a reassessment Targeting the Wnt pathway in human cancers: therapeutic targeting with a focus on OMP-54F28 Can nanomedicines kill cancer stem cells?The pathogenesis of chronic lymphocytic leukemia Quantitative phenotyping-based in vivo chemical screening in a zebrafish model of leukemia stem cell xenotransplantation Inhibition of oncogenic Wnt signaling through direct targeting of -catenin The EMT activator ZEB1 promotes tumor growth and determines differential response to chemotherapy in mantle cell lymphoma.Therapeutic targets of triple-negative breast cancer: a review Role of the Wnt/β-catenin pathway in gastric cancer: An in-depth literature review Niclosamide suppresses cancer cell growth by inducing Wnt co-receptor LRP6 degradation and inhibiting the Wnt/β-catenin pathway Inhibitory Effects of Salinomycin on Cell Survival, Colony Growth, Migration, and Invasion of Human Non-Small Cell Lung Cancer A549 and LNM35: Involvement of NAG-1 Salinomycin activates AMP-activated protein kinase-dependent autophagy in cultured osteoblastoma cells: a negative regulator against cell apoptosis Salinomycin potentiates the cytotoxic effects of TRAIL on glioblastoma cell lines Inhibition of autophagic flux by salinomycin results in anti-cancer effect in hepatocellular carcinoma cells A novel anticancer agent SNG1153 inhibits growth of lung cancer stem/progenitor cells Roles of Wnt/β-catenin signaling in the gastric cancer stem cells proliferation and salinomycin treatment.Concise review: breast cancer stem cells: regulatory networks, stem cell niches, and disease relevance Sensitization of cancer cells through reduction of total Akt and downregulation of salinomycin-induced pAkt, pGSk3β, pTSC2, and p4EBP1 by cotreatment with MK-2206.Systemic approaches identify a garlic-derived chemical, Z-ajoene, as a glioblastoma multiforme cancer stem cell-specific targeting agent.Salinomycin suppresses LRP6 expression and inhibits both Wnt/β-catenin and mTORC1 signaling in breast and prostate cancer cells A late-stage intermediate in salinomycin biosynthesis is revealed by specific mutation in the biosynthetic gene cluster.Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors.iTEP nanoparticle-delivered salinomycin displays an enhanced toxicity to cancer stem cells in orthotopic breast tumors.Impact of Salinomycin on human cholangiocarcinoma: induction of apoptosis and impairment of tumor cell proliferation in vitro Salinomycin inhibits proliferation and induces apoptosis of human hepatocellular carcinoma cells in vitro and in vivo.Salinomycin inhibited cell proliferation and induced apoptosis in human uterine leiomyoma cells.Salinomycin Suppresses PDGFRβ, MYC, and Notch Signaling in Human Medulloblastoma.The C-terminal region Mesd peptide mimics full-length Mesd and acts as an inhibitor of Wnt/β-catenin signaling in cancer cells.New cell-signaling pathways for controlling cytomegalovirus replication.Wnt signaling is involved in 6-benzylthioinosine-induced AML cell differentiation.Synthetic modification of salinomycin: selective O-acylation and biological evaluation.Salinomycin and other polyether ionophores are a new class of antiscarring agent Integrated β-catenin, BMP, PTEN, and Notch signalling patterns the nephron.Getting to the source: selective drug targeting of cancer stem cells.

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P2860

Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells.

http://www.wikidata.org/entity/Q35164584

description

2011 nî lūn-bûn

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2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2011 թվականի հուլիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Salinomycin inhibits Wnt signa ...... ic lymphocytic leukemia cells.

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Salinomycin inhibits Wnt signa ...... ic lymphocytic leukemia cells.

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type

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Salinomycin inhibits Wnt signa ...... ic lymphocytic leukemia cells.

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Salinomycin inhibits Wnt signa ...... ic lymphocytic leukemia cells.

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prefLabel

Salinomycin inhibits Wnt signa ...... ic lymphocytic leukemia cells.

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Salinomycin inhibits Wnt signa ...... ic lymphocytic leukemia cells.

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Proceedings of the National Academy of Sciences of the United States of America

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Salinomycin inhibits Wnt signa ...... ic lymphocytic leukemia cells.

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P2093

Dennis A Carson

http://www.w3.org/2001/XMLSchema#string

Desheng Lu

http://www.w3.org/2001/XMLSchema#string

Januario E Castro

http://www.w3.org/2001/XMLSchema#string

Jian Yu

http://www.w3.org/2001/XMLSchema#string

Michael Y Choi

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Thomas J Kipps

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P2860

LDL-receptor-related proteins in Wnt signal transduction

Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling

Transmembrane protein 198 promotes LRP6 phosphorylation and Wnt signaling activation

Small molecule inhibitors of Wnt/beta-catenin/lef-1 signaling induces apoptosis in chronic lymphocytic leukemia cells in vitro and in vivo

Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia

Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains

Wnt/beta-catenin signaling in development and disease

Wnt signaling and cancer

Stem cells, cancer, and cancer stem cells

LDL-receptor-related protein 6 is a receptor for Dickkopf proteins

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21788521

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