Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells.
about
Salinomycin as a drug for targeting human cancer stem cellsA Second WNT for Old Drugs: Drug Repositioning against WNT-Dependent CancersAnti-Cancer Stem-like Cell Compounds in Clinical Development - An Overview and Critical AppraisalCancer stem cells--important players in tumor therapy resistanceIdentifying and targeting tumor-initiating cells in the treatment of breast cancerSalinomycin: a novel anti-cancer agent with known anti-coccidial activitiesThe Valley of Death in anticancer drug development: a reassessmentTargeting the Wnt pathway in human cancers: therapeutic targeting with a focus on OMP-54F28Can nanomedicines kill cancer stem cells?The pathogenesis of chronic lymphocytic leukemiaQuantitative phenotyping-based in vivo chemical screening in a zebrafish model of leukemia stem cell xenotransplantationInhibition of oncogenic Wnt signaling through direct targeting of -cateninThe EMT activator ZEB1 promotes tumor growth and determines differential response to chemotherapy in mantle cell lymphoma.Therapeutic targets of triple-negative breast cancer: a reviewRole of the Wnt/β-catenin pathway in gastric cancer: An in-depth literature reviewNiclosamide suppresses cancer cell growth by inducing Wnt co-receptor LRP6 degradation and inhibiting the Wnt/β-catenin pathwayInhibitory Effects of Salinomycin on Cell Survival, Colony Growth, Migration, and Invasion of Human Non-Small Cell Lung Cancer A549 and LNM35: Involvement of NAG-1Salinomycin activates AMP-activated protein kinase-dependent autophagy in cultured osteoblastoma cells: a negative regulator against cell apoptosisSalinomycin potentiates the cytotoxic effects of TRAIL on glioblastoma cell linesInhibition of autophagic flux by salinomycin results in anti-cancer effect in hepatocellular carcinoma cellsA novel anticancer agent SNG1153 inhibits growth of lung cancer stem/progenitor cellsRoles of Wnt/β-catenin signaling in the gastric cancer stem cells proliferation and salinomycin treatment.Concise review: breast cancer stem cells: regulatory networks, stem cell niches, and disease relevanceSensitization of cancer cells through reduction of total Akt and downregulation of salinomycin-induced pAkt, pGSk3β, pTSC2, and p4EBP1 by cotreatment with MK-2206.Systemic approaches identify a garlic-derived chemical, Z-ajoene, as a glioblastoma multiforme cancer stem cell-specific targeting agent.Salinomycin suppresses LRP6 expression and inhibits both Wnt/β-catenin and mTORC1 signaling in breast and prostate cancer cellsA late-stage intermediate in salinomycin biosynthesis is revealed by specific mutation in the biosynthetic gene cluster.Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors.iTEP nanoparticle-delivered salinomycin displays an enhanced toxicity to cancer stem cells in orthotopic breast tumors.Impact of Salinomycin on human cholangiocarcinoma: induction of apoptosis and impairment of tumor cell proliferation in vitroSalinomycin inhibits proliferation and induces apoptosis of human hepatocellular carcinoma cells in vitro and in vivo.Salinomycin inhibited cell proliferation and induced apoptosis in human uterine leiomyoma cells.Salinomycin Suppresses PDGFRβ, MYC, and Notch Signaling in Human Medulloblastoma.The C-terminal region Mesd peptide mimics full-length Mesd and acts as an inhibitor of Wnt/β-catenin signaling in cancer cells.New cell-signaling pathways for controlling cytomegalovirus replication.Wnt signaling is involved in 6-benzylthioinosine-induced AML cell differentiation.Synthetic modification of salinomycin: selective O-acylation and biological evaluation.Salinomycin and other polyether ionophores are a new class of antiscarring agentIntegrated β-catenin, BMP, PTEN, and Notch signalling patterns the nephron.Getting to the source: selective drug targeting of cancer stem cells.
P2860
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P2860
Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Salinomycin inhibits Wnt signa ...... ic lymphocytic leukemia cells.
@ast
Salinomycin inhibits Wnt signa ...... ic lymphocytic leukemia cells.
@en
type
label
Salinomycin inhibits Wnt signa ...... ic lymphocytic leukemia cells.
@ast
Salinomycin inhibits Wnt signa ...... ic lymphocytic leukemia cells.
@en
prefLabel
Salinomycin inhibits Wnt signa ...... ic lymphocytic leukemia cells.
@ast
Salinomycin inhibits Wnt signa ...... ic lymphocytic leukemia cells.
@en
P2093
P2860
P356
P1476
Salinomycin inhibits Wnt signa ...... ic lymphocytic leukemia cells.
@en
P2093
Dennis A Carson
Desheng Lu
Januario E Castro
Michael Y Choi
Thomas J Kipps
P2860
P304
13253-13257
P356
10.1073/PNAS.1110431108
P407
P577
2011-07-25T00:00:00Z