G protein-coupled receptor kinase 5 phosphorylation of hip regulates internalization of the chemokine receptor CXCR4
about
G-protein-coupled receptor kinases in inflammation and diseaseStructure and function of Hip, an attenuator of the Hsp70 chaperone cycleA genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans.A high-content, live-cell, and real-time approach to the quantitation of ligand-induced β-Arrestin2 and Class A/Class B GPCR mobilization.β-Arrestin1 and distinct CXCR4 structures are required for stromal derived factor-1 to downregulate CXCR4 cell-surface levels in neuroblastomaCysteine (C)-x-C receptor 4 undergoes transportin 1-dependent nuclear localization and remains functional at the nucleus of metastatic prostate cancer cellsNuclear translocation of cardiac G protein-Coupled Receptor kinase 5 downstream of select Gq-activating hypertrophic ligands is a calmodulin-dependent process.Hierarchical organization of multi-site phosphorylation at the CXCR4 C terminus.G protein-coupled receptor kinase 5 phosphorylates nucleophosmin and regulates cell sensitivity to polo-like kinase 1 inhibition.The chemokine receptors CXCR1 and CXCR2 couple to distinct G protein-coupled receptor kinases to mediate and regulate leukocyte functions.The WIP1 oncogene promotes progression and invasion of aggressive medulloblastoma variantsG protein-coupled receptor kinase 2 (GRK2) is localized to centrosomes and mediates epidermal growth factor-promoted centrosomal separation.Genetic Determinants of Type 2 Diabetes in AsiansMechanisms of Regulation of the Chemokine-Receptor Network.G-protein-coupled receptor kinase-5 mediates inflammation but does not regulate cellular infiltration or bacterial load in a polymicrobial sepsis model in mice.Rapid uptake and degradation of CXCL12 depend on CXCR7 carboxyl-terminal serine/threonine residues.G Protein-Coupled Receptor Kinases in the Inflammatory Response and Signaling.The Role of G Protein-coupled Receptor Kinases in Cancer.A single amino acid substitution in CXCL12 confers functional selectivity at the beta-arrestin level.
P2860
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P2860
G protein-coupled receptor kinase 5 phosphorylation of hip regulates internalization of the chemokine receptor CXCR4
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
G protein-coupled receptor kin ...... f the chemokine receptor CXCR4
@ast
G protein-coupled receptor kin ...... f the chemokine receptor CXCR4
@en
type
label
G protein-coupled receptor kin ...... f the chemokine receptor CXCR4
@ast
G protein-coupled receptor kin ...... f the chemokine receptor CXCR4
@en
prefLabel
G protein-coupled receptor kin ...... f the chemokine receptor CXCR4
@ast
G protein-coupled receptor kin ...... f the chemokine receptor CXCR4
@en
P2860
P356
P1433
P1476
G protein-coupled receptor kin ...... f the chemokine receptor CXCR4
@en
P2093
Breann L Barker
Jeffrey L Benovic
P2860
P304
P356
10.1021/BI2005202
P407
P577
2011-07-12T00:00:00Z