Heme-dependent activation of neuronal nitric oxide synthase by cytosol is due to an Hsp70-dependent, thioredoxin-mediated thiol-disulfide interchange in the heme/substrate binding cleft
about
Targeting Hsp90/Hsp70-based protein quality control for treatment of adult onset neurodegenerative diseasesStructural basis for the inhibition of HSP70 and DnaK chaperones by small-molecule targeting of a C-terminal allosteric pocketA model in which heat shock protein 90 targets protein-folding clefts: rationale for a new approach to neuroprotective treatment of protein folding diseasesActivation of Hsp70 reduces neurotoxicity by promoting polyglutamine protein degradationEngineering therapeutic protein disaggregases.Destabilization of the epidermal growth factor receptor (EGFR) by a peptide that inhibits EGFR binding to heat shock protein 90 and receptor dimerization.Dissecting regulation mechanism of the FMN to heme interdomain electron transfer in nitric oxide synthases.Specific Binding of Tetratricopeptide Repeat Proteins to Heat Shock Protein 70 (Hsp70) and Heat Shock Protein 90 (Hsp90) Is Regulated by Affinity and Phosphorylation.Mapping interactions with the chaperone network reveals factors that protect against tau aggregation
P2860
Q26859909-043AEF13-C290-4731-9A75-1F57D72415D7Q28246523-B53620E3-6352-4120-9825-EC3421082394Q35053633-D8A4FD65-FFD7-47F1-8DBA-8AF836900807Q36553586-C8930BAB-C4B6-4E6C-88E6-95E2EA66A388Q36896295-F655CDED-F5F4-4CB5-B97D-02E34F41BA9FQ37168481-61CCA3FC-6184-4489-9074-B882276D902EQ37350981-89360DA2-DE5C-4969-AEC8-A595F4E294F3Q41884789-5DC58C29-1709-4D6C-BCAE-C3FE5565C420Q57560752-AB8A64FD-07DF-4B8B-8302-871907A9B879
P2860
Heme-dependent activation of neuronal nitric oxide synthase by cytosol is due to an Hsp70-dependent, thioredoxin-mediated thiol-disulfide interchange in the heme/substrate binding cleft
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Heme-dependent activation of n ...... e heme/substrate binding cleft
@ast
Heme-dependent activation of n ...... e heme/substrate binding cleft
@en
type
label
Heme-dependent activation of n ...... e heme/substrate binding cleft
@ast
Heme-dependent activation of n ...... e heme/substrate binding cleft
@en
prefLabel
Heme-dependent activation of n ...... e heme/substrate binding cleft
@ast
Heme-dependent activation of n ...... e heme/substrate binding cleft
@en
P2093
P2860
P356
P1433
P1476
Heme-dependent activation of n ...... e heme/substrate binding cleft
@en
P2093
Hwei-Ming Peng
Jason E Gestwicki
Miranda Lau
William B Pratt
Yoichi Osawa
Yoshihiro Morishima
Yoshinari Miyata
P2860
P304
P356
10.1021/BI200751T
P407
P577
2011-07-21T00:00:00Z