GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodeling - Wikidata - awgldk - TriplyDB

GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodeling

GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodeling

http://www.wikidata.org/entity/Q35170832

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A key commitment step in erythropoiesis is synchronized with the cell cycle clock through mutual inhibition between PU.1 and S-phase progression Knockdown of ZNF268, which is transcriptionally downregulated by GATA-1, promotes proliferation of K562 cells GATA-1 forms distinct activating and repressive complexes in erythroid cells Insights into association of the NuRD complex with FOG-1 from the crystal structure of an RbAp48·FOG-1 complex GATA-1 mediates auto-regulation of Gfi-1B transcription in K562 cells Jun blockade of erythropoiesis: role for repression of GATA-1 by HERP2.Transcription factors KLF1 and KLF2 positively regulate embryonic and fetal beta-globin genes through direct promoter binding miR-451 regulates zebrafish erythroid maturation in vivo via its target gata2 Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies Exploiting genomics and natural genetic variation to decode macrophage enhancers Transcription factor-mediated reprogramming toward hematopoietic stem cells Expression and potential role of GATA factors in trophoblast development The emerging role of GATA transcription factors in development and disease Erythro-megakaryocytic transcription factors associated with hereditary anemia Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes Autophagy driven by a master regulator of hematopoiesis Transcription factor GATA-1 and Down syndrome leukemogenesis FOG-1 recruits the NuRD repressor complex to mediate transcriptional repression by GATA-1.Discovering hematopoietic mechanisms through genome-wide analysis of GATA factor chromatin occupancy Insights into GATA-1-mediated gene activation versus repression via genome-wide chromatin occupancy analysis SON protein regulates GATA-2 through transcriptional control of the microRNA 23a~27a~24-2 cluster GATA switches as developmental drivers Mi2β is required for γ-globin gene silencing: temporal assembly of a GATA-1-FOG-1-Mi2 repressor complex in β-YAC transgenic mice Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development Mast cell lineage diversion of T lineage precursors by the essential T cell transcription factor GATA-3 Chemical Inhibition of Histone Deacetylases 1 and 2 Induces Fetal Hemoglobin through Activation of GATA2 Molecular hallmarks of endogenous chromatin complexes containing master regulators of hematopoiesis SCL and associated proteins distinguish active from repressive GATA transcription factor complexes FOG-1-mediated recruitment of NuRD is required for cell lineage re-enforcement during haematopoiesis GATA2 regulates body water homeostasis through maintaining aquaporin 2 expression in renal collecting ducts.Inducible Gata1 suppression expands megakaryocyte-erythroid progenitors from embryonic stem cells.A hyperactive transcriptional state marks genome reactivation at the mitosis-G1 transition.Synthesis and selection of de novo proteins that bind and impede cellular functions of an essential mycobacterial protein.Differential requirements for the activation domain and FOG-interaction surface of GATA-1 in megakaryocyte gene expression and development Characterization of megakaryocyte GATA1-interacting proteins: the corepressor ETO2 and GATA1 interact to regulate terminal megakaryocyte maturation GATA factor mutations in hematologic disease.Integrating extrinsic and intrinsic cues into a minimal model of lineage commitment for hematopoietic progenitors.Modeling reveals bistability and low-pass filtering in the network module determining blood stem cell fate.A computational evaluation of over-representation of regulatory motifs in the promoter regions of differentially expressed genes.The leukemia associated ETO nuclear repressor gene is regulated by the GATA-1 transcription factor in erythroid/megakaryocytic cells.

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P2860

GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodeling

http://www.wikidata.org/entity/Q35170832

description

2003 nî lūn-bûn

@nan

2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի հուլիսին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

@zh-hant

2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

GATA-1-dependent transcription ...... main-wide chromatin remodeling

@ast

GATA-1-dependent transcription ...... main-wide chromatin remodeling

@en

type

label

GATA-1-dependent transcription ...... main-wide chromatin remodeling

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GATA-1-dependent transcription ...... main-wide chromatin remodeling

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prefLabel

GATA-1-dependent transcription ...... main-wide chromatin remodeling

@ast

GATA-1-dependent transcription ...... main-wide chromatin remodeling

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P356

PNAS.1432147100

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

GATA-1-dependent transcription ...... main-wide chromatin remodeling

@en

P2093

Emery H Bresnick

http://www.w3.org/2001/XMLSchema#string

Jeffrey A Grass

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Jing Wu

http://www.w3.org/2001/XMLSchema#string

Meghan E Boyer

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Saumen Pal

http://www.w3.org/2001/XMLSchema#string

P2860

Essential and instructive roles of GATA factors in eosinophil development

A palindromic regulatory site within vertebrate GATA-1 promoters requires both zinc fingers of the GATA-1 DNA-binding domain for high-affinity interaction

The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins

Transcriptional cofactors of the FOG family interact with GATA proteins by means of multiple zinc fingers

DNA-binding specificities of the GATA transcription factor family

Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1

Reciprocal interactions of Pit1 and GATA2 mediate signaling gradient-induced determination of pituitary cell types

Histone deacetylase 3 associates with and represses the transcription factor GATA-2

Transcriptional regulation of erythropoiesis: an affair involving multiple partners

FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation

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15

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P478

100

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P50

Mitchell J Weiss

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10664115

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12857954

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166395

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