Of mice and not humans: how reliable are animal models for evaluation of herpes CD8(+)-T cell-epitopes-based immunotherapeutic vaccine candidates?
about
Towards a rational design of an asymptomatic clinical herpes vaccine: the old, the new, and the unknownThe molecular basis of herpes simplex virus latencyParticulate delivery systems for vaccination against bioterrorism agents and emerging infectious pathogensA cultured affair: HSV latency and reactivation in neuronsThe challenges and opportunities for the development of a T-cell epitope-based herpes simplex vaccineInduction of interferon-λ contributes to TLR3 and RIG-I activation-mediated inhibition of herpes simplex virus type 2 replication in human cervical epithelial cells.Asymptomatic HLA-A*02:01-restricted epitopes from herpes simplex virus glycoprotein B preferentially recall polyfunctional CD8+ T cells from seropositive asymptomatic individuals and protect HLA transgenic mice against ocular herpes.Associations of HLA-A, HLA-B and HLA-C alleles frequency with prevalence of herpes simplex virus infections and diseases across global populations: implication for the development of an universal CD8+ T-cell epitope-based vaccine.Prospects and perspectives for development of a vaccine against herpes simplex virus infections.Intravaginal Zinc Oxide Tetrapod Nanoparticles as Novel Immunoprotective Agents against Genital Herpes.Human sensory neurons derived from induced pluripotent stem cells support varicella-zoster virus infection.HLA-A02:01-restricted epitopes identified from the herpes simplex virus tegument protein VP11/12 preferentially recall polyfunctional effector memory CD8+ T cells from seropositive asymptomatic individuals and protect humanized HLA-A*02:01 transgeniPhenotypic and functional characterization of herpes simplex virus glycoprotein B epitope-specific effector and memory CD8+ T cells from symptomatic and asymptomatic individuals with ocular herpesThe Current State of Vaccine Development for Ocular HSV-1 InfectionTherapeutic immunization with a mixture of herpes simplex virus 1 glycoprotein D-derived “asymptomatic” human CD8+ T-cell epitopes decreases spontaneous ocular shedding in latently infected HLA transgenic rabbits: association with low frequency of lA Herpes Simplex Virus Type 1 Human Asymptomatic CD8+ T-Cell Epitopes-Based Vaccine Protects Against Ocular Herpes in a "Humanized" HLA Transgenic Rabbit Model.Future of an "Asymptomatic" T-cell Epitope-Based Therapeutic Herpes Simplex VaccineTargeting the genital tract mucosa with a lipopeptide/recombinant adenovirus prime/boost vaccine induces potent and long-lasting CD8+ T cell immunity against herpes: importance of MyD88.Confocal Microscopic Analysis of a Rabbit Eye Model of High-Incidence Recurrent Herpes Stromal Keratitis.Herpes Simplex Virus 1 Infection of Tree Shrews Differs from That of Mice in the Severity of Acute Infection and Viral Transcription in the Peripheral Nervous SystemMucosal herpes immunity and immunopathology to ocular and genital herpes simplex virus infections.Current trends in negative immuno-synergy between two sexually transmitted infectious viruses: HIV-1 and HSV-1/2.Humanized mice for the study of infectious diseases.Experimental infection of New Zealand white rabbits (Oryctolagus cuniculi) with Leporid herpesvirus 4Evaluation of tissue interactions with mechanical elements of a transscleral drug delivery device.Human Asymptomatic Epitopes Identified from the Herpes Simplex Virus Tegument Protein VP13/14 (UL47) Preferentially Recall Polyfunctional Effector Memory CD44high CD62Llow CD8+ TEM Cells and Protect Humanized HLA-A*02:01 Transgenic Mice against OculPrior Corneal Scarification and Injection of Immune Serum are Not Required Before Ocular HSV-1 Infection for UV-B-Induced Virus Reactivation and Recurrent Herpetic Corneal Disease in Latently Infected Mice.Herpes simplex virus infects most cell types in vitro: clues to its successThe reproducibility of biomedical research: Sleepers awake!Bolstering the Number and Function of HSV-1-Specific CD8+ Effector Memory T Cells and Tissue-Resident Memory T Cells in Latently Infected Trigeminal Ganglia Reduces Recurrent Ocular Herpes Infection and Disease.CXCL10/CXCR3-Dependent Mobilization of Herpes Simplex Virus-Specific CD8+ TEM and CD8+ TRM Cells within Infected Tissues Allows Efficient Protection against Recurrent Herpesvirus Infection and Disease.CXCL17 Chemokine-Dependent Mobilization of CXCR8+CD8+ Effector Memory and Tissue-Resident Memory T Cells in the Vaginal Mucosa Is Associated with Protection against Genital Herpes.The wide utility of rabbits as models of human diseases.Human Asymptomatic Epitope Peptide/CXCL10-Based Prime/Pull Vaccine Induces Herpes Simplex Virus-Specific Gamma Interferon-Positive CD107 CD8 T Cells That Infiltrate the Corneas and Trigeminal Ganglia of Humanized HLA Transgenic Rabbits and Protect ag
P2860
Q21296712-399A7CC2-61CC-493D-B91B-7E40B66EEC17Q27001272-84F606DA-89B1-4313-8F37-5642FA13EE5EQ27011190-F7847754-E531-488F-83A4-E58E98DFF82BQ27015883-364C01B8-4D20-491A-82E7-ED3C899D4E06Q27021292-6A20EA4B-5BF8-4C75-8B4B-D8BC28313A05Q30683907-1F5D76E2-4FD9-4FF0-86B1-BFACA3BE0869Q33755236-2F20D663-C992-4CC2-9155-E03B4A3FBB83Q33993731-7A218A09-541E-439C-939F-78C41F099880Q34431547-F9FCD5F7-D6BA-44D3-8784-C870516BF375Q34526716-6200FFAE-49E5-4C86-8E56-41F3A664D8A0Q34534963-8F9415F2-C172-41EE-9070-8E54CBF63CA1Q35122383-1F28590F-D3EB-40C1-A001-BF860EFC96E9Q35487893-1175458A-2E18-4E93-BE50-AEFED1D3EC27Q35606611-8FCC9B55-9004-42EF-B6F8-D9849A7E79F2Q35745358-24CBB3ED-8048-4B4D-8451-BF2819C2D77BQ35769258-A3087517-25AF-433F-A444-A85BBF7A0DD5Q36025675-A8513AAF-CF95-4F40-A162-6935F0A51371Q36339059-7FFBDD69-00D0-42AE-BBF4-DDCD3513DEB7Q36359783-368BFBC1-11F4-4AEB-8F60-3CC1307F5C87Q36434241-882693FE-43F5-4830-AC99-DC2E20D64A30Q36520832-45406CE2-63ED-4800-8D25-1E2779955ABCQ36555158-45DB0082-6AD4-4B90-A827-AE5336654FA6Q37179146-21090188-506E-4FFC-B0EE-C6B7041162ACQ37230066-60AF4BB5-74EE-476E-B60E-C44019782817Q37327804-F17CF23D-7630-4096-A5CF-BE2414FB1605Q37560770-0E863FAF-E79B-405E-B762-AAD00E5A0C2CQ37699104-15EF3BE4-87E2-4E33-8834-F2AACE7A5D0CQ37949631-6A5D782C-BD8C-425C-8BE1-5AD4F9E69D16Q39023051-2F18F92A-AD1D-4643-BDBA-FE3355B4E67BQ40187650-82AC977A-7AB7-4832-A2E0-D45ACE5DDE1EQ40216595-D75AFAAA-FBB7-4D7B-8E0B-8FFEAEFF465CQ54254466-28CEBB25-68FB-4DCE-A729-EAD6F3AAC3E8Q55250836-9F5CF5F1-DB8C-4F59-ABDA-6892E91CAEF7Q57753552-9F865577-5308-49FB-855C-764E3BD966A9
P2860
Of mice and not humans: how reliable are animal models for evaluation of herpes CD8(+)-T cell-epitopes-based immunotherapeutic vaccine candidates?
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Of mice and not humans: how re ...... herapeutic vaccine candidates?
@ast
Of mice and not humans: how re ...... herapeutic vaccine candidates?
@en
type
label
Of mice and not humans: how re ...... herapeutic vaccine candidates?
@ast
Of mice and not humans: how re ...... herapeutic vaccine candidates?
@en
prefLabel
Of mice and not humans: how re ...... herapeutic vaccine candidates?
@ast
Of mice and not humans: how re ...... herapeutic vaccine candidates?
@en
P2860
P1433
P1476
Of mice and not humans: how re ...... herapeutic vaccine candidates?
@en
P2093
Gargi Dasgupta
Lbachir BenMohamed
P2860
P304
P356
10.1016/J.VACCINE.2011.06.083
P407
P577
2011-06-28T00:00:00Z